公开(公告)号：US10421822B2

公开(公告)日：2019-09-24

申请号：US16168503

申请日：2018-10-23

Applicant: Genentech, Inc.

Inventor： Robert F. Kelley ,  Daniel K. Kirchhofer ,  Joyce Lai ,  Chingwei V. Lee ,  Wei-Ching Liang ,  Michael T. Lipari ,  Kelly M. Loyet ,  Tao Sai ,  Menno Van Lookeren Campagne ,  Yan Wu ,  Germaine Fuh

IPC: C07K16/40 ,  A61K39/395 ,  A61K39/00

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

公开(公告)号：US20230383008A1

公开(公告)日：2023-11-30

申请号：US18048763

申请日：2022-10-21

Applicant: Genentech, Inc.

Inventor： Robert F. KELLEY ,  Daniel K. Kirchhofer ,  Joyce Lai ,  Chingwei V. Lee ,  Wei-Ching Liang ,  Michael T. Lipari ,  Kelly M. Loyet ,  Tao Sai ,  Menno Van Lookeren Campagne ,  Yan Wu ,  Germaine Fuh

IPC: C07K16/40 ,  A61K39/395

CPC classification number: C07K16/40 ,  A61K39/3955 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  A61K2039/507

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

公开(公告)号：US11512143B2

公开(公告)日：2022-11-29

申请号：US16543818

申请日：2019-08-19

Applicant: Genentech, Inc.

Inventor： Robert F. Kelley ,  Daniel K. Kirchhofer ,  Joyce Lai ,  Chingwei V. Lee ,  Wei-Ching Liang ,  Michael T. Lipari ,  Kelly M. Loyet ,  Tao Sai ,  Menno Van Lookeren Campagne ,  Yan Wu ,  Germaine Fuh

IPC: C07K16/40 ,  A61K39/395 ,  A61K39/00

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

公开(公告)号：US10421821B2

公开(公告)日：2019-09-24

申请号：US15336171

申请日：2016-10-27

Applicant: Genentech, Inc.

Inventor： Robert F. Kelley ,  Daniel K. Kirchhofer ,  Joyce Lai ,  Chingwei V. Lee ,  Wei-Ching Liang ,  Michael T. Lipari ,  Kelly M. Loyet ,  Tao Sai ,  Menno Van Lookeren Campagne ,  Yan Wu ,  Germaine Fuh

IPC: A61K39/00 ,  A61K39/395 ,  C07K16/40

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

公开(公告)号：US20190048097A1

公开(公告)日：2019-02-14

申请号：US16168503

申请日：2018-10-23

Applicant: Genentech, Inc.

Inventor： Robert F. Kelley ,  Daniel K. Kirchhofer ,  Joyce Lai ,  Chingwei V. Lee ,  Wei-Ching Liang ,  Michael T. Lipari ,  Kelly M. Loyet ,  Tao Sai ,  Menno Van Lookeren Campagne ,  Yan Wu ,  Germaine Fuh

IPC: C07K16/40 ,  A61K39/00

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61K2039/507 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/53 ,  C07K2317/55 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.