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公开(公告)号:US20240368306A1
公开(公告)日:2024-11-07
申请号:US18439879
申请日:2024-02-13
Applicant: Genentech, Inc.
Inventor: Xiaocheng CHEN , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26 , C07K16/24
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号:US11866496B2
公开(公告)日:2024-01-09
申请号:US17234695
申请日:2021-04-19
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
CPC classification number: C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , C07K16/2896 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/30
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20220204640A1
公开(公告)日:2022-06-30
申请号:US17655136
申请日:2022-03-16
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Bonnee Rubinfeld , Paul Polakis
IPC: C07K16/30 , C07K16/28 , G01N33/574 , A61K45/06 , C07K16/18 , A61K31/537 , A61K47/68
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US11167038B2
公开(公告)日:2021-11-09
申请号:US16033489
申请日:2018-07-12
Applicant: Genentech, Inc.
Inventor: Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
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公开(公告)号:US20200255539A1
公开(公告)日:2020-08-13
申请号:US16721525
申请日:2019-12-19
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , G01N33/574 , C07K16/30 , A61K49/00 , A61K31/704 , A61K31/675 , A61K31/5517 , C07K16/28 , A61K39/395 , A61K47/68
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20200085840A1
公开(公告)日:2020-03-19
申请号:US16391738
申请日:2019-04-23
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K31/5517 , A61K47/68 , A61K39/395 , C07K16/00 , C07K16/32
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号:US10314846B2
公开(公告)日:2019-06-11
申请号:US15438418
申请日:2017-02-21
Applicant: GENENTECH, INC.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K39/395 , A61K31/5517 , A61K47/68 , C07K16/00 , C07K16/32
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号:US20190030160A1
公开(公告)日:2019-01-31
申请号:US16033489
申请日:2018-07-12
Applicant: Genentech, Inc.
Inventor: Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
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公开(公告)号:US20180291104A1
公开(公告)日:2018-10-11
申请号:US15721227
申请日:2017-09-29
Applicant: Genentech, Inc.
Inventor: Sherman Fong , Mark Dennis
Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies.
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公开(公告)号:US09896506B2
公开(公告)日:2018-02-20
申请号:US14734957
申请日:2015-06-09
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K47/68 , A61K38/05 , A61K45/06 , A61K51/10 , G01N33/574 , A61K31/537 , A61K39/00
CPC classification number: C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals, including immunoconjugates comprising anti-CD79b cysteine-engineered antibody huMA79b.v28, and to methods of using those compositions of matter for the same.
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