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公开(公告)号：US20230416825A1
公开(公告)日：2023-12-28
申请号：US18192505
申请日：2023-03-29
Applicant: Genentech, Inc.
Inventor： Amy Dressen , David B. Iaea , Moulay Hicham Alaoui Ismaili , Janet K. Jackman , Robert A. Lazarus , Kelly Michele Loyet , Henry R. Maun , Brian Louis Yaspan , Tangsheng Yi , Joseph R. Arron , Hilda Y Hernandez-Barry
IPC: C12Q1/6883 , C07K16/40 , C07K14/81 , G01N33/68 , C12N9/64
CPC classification number: C12Q1/6883 , C07K16/40 , C07K14/8135 , G01N33/6893 , C12N9/6445 , C12Q2600/106 , C12Q2600/156 , A61K38/00
Abstract: Provided herein are methods of treating a subject, methods of predicting the response of a subject and selecting a subject suffering from a disease associated with KLK5, such as asthma or Netherton Syndrome. In particular, provided herein are uses of KLK5 antagonists for the treatment or diagnosis of asthma or Netherton Sydrome, such as an antibody or an Fc fusion polypeptide as well as pharmaceutical formulations comprising the same.
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公开(公告)号：US11939396B2
公开(公告)日：2024-03-26
申请号：US16916822
申请日：2020-06-30
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , C07K16/24 , A61K39/00 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26
CPC classification number: C07K16/40 , A61K39/3955 , A61K39/39591 , C07K16/244 , C12Y304/21059 , A61K2039/505 , A61K45/06 , A61K47/10 , A61K47/183 , A61K47/22 , A61K47/26 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US10738131B2
公开(公告)日：2020-08-11
申请号：US15893238
申请日：2018-02-09
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , A61K47/18 , A61K47/22 , A61K47/26 , A61K47/10 , A61K45/06 , C07K16/24 , A61K39/00
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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Patent Agency Ranking
公开(公告)号：US20240368306A1
公开(公告)日：2024-11-07
申请号：US18439879
申请日：2024-02-13
Applicant: Genentech, Inc.
Inventor： Xiaocheng CHEN , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26 , C07K16/24
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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5.发明公开公开(公告)号：US20240084042A1
公开(公告)日：2024-03-14
申请号：US18464580
申请日：2023-09-11
Applicant: Genentech, Inc.
Inventor： James Thomas Koerber , Wyne Pun Lee , Tangsheng Yi , Juan Zhang , Cary Dean Austin , Cecilia Pui Chi Chiu , Joseph Edward Chavarria-Smith , Jawahar Sudhamsu
CPC classification number: C07K16/468 , A61P29/00 , C07K2317/14 , C07K2317/31 , C07K2317/565
Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.
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公开(公告)号：US20210130492A1
公开(公告)日：2021-05-06
申请号：US17024094
申请日：2020-09-17
Applicant: Genentech, Inc.
Inventor： James Thomas Koerber , Wyne Pun Lee , Tangsheng Yi , Juan Zhang , Cary Dean Austin , Cecilia P.C. Chiu , Joseph Chavarria-Smith , Jawahar Sudhamsu
IPC: C07K16/40 , A61K39/395 , A61P17/00
Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.
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公开(公告)号：US10752703B2
公开(公告)日：2020-08-25
申请号：US16544421
申请日：2019-08-19
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , A61K39/00 , A61K47/18 , A61K47/22 , A61K47/26 , A61K47/10 , A61K45/06 , C07K16/24
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US20190078160A1
公开(公告)日：2019-03-14
申请号：US15958696
申请日：2018-04-20
Applicant: Genentech, Inc.
Inventor： Amy Dressen , David B. Iaea , Moulay Hicham Alaoui Ismaili , Janet K. Jackman , Robert A. Lazarus , Kelly Loyet , Henry R. Maun , Brian L. Yaspan , Tangsheng Yi , Joseph R. Arron , Hilda Y. Hernandez-Barry
IPC: C12Q1/6883
Abstract: Provided herein are methods of treating a subject, methods of predicting the response of a subject and selecting a subject suffering from a disease associated with KLK5, such as asthma or Netherton Syndrome. In particular, provided herein are uses of KLK5 antagonists for the treatment or diagnosis of asthma or Netherton Syndrome, such as an antibody or an Fc fusion polypeptide as well as pharmaceutical formulations comprising the same.
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