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公开(公告)号：US20210213130A1
公开(公告)日：2021-07-15
申请号：US17129096
申请日：2020-12-21
Applicant: GENENTECH, INC.
Inventor： Gail Lewis Phillips , Deepak Sampath , Ingrid Wertz
IPC: A61K39/395 , C07K16/32 , G01N33/574 , A61K47/68 , A61K31/635 , A61K45/06 , A61P35/00 , A61K31/496
Abstract: The present invention is directed to a combination therapy involving an anti-HER2 antibody-drug conjugate and a selective Bcl-2 inhibitor for the treatment of a patient suffering from cancer, particularly, a HER2-expressing cancer.
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公开(公告)号：US20180140700A1
公开(公告)日：2018-05-24
申请号：US15849018
申请日：2017-12-20
Applicant: Genentech, Inc.
Inventor： Gail Lewis Phillips , Deepak Sampath , Ingrid Wertz
IPC: A61K39/395 , A61K31/496 , A61K47/68 , C07K16/32 , A61P35/00 , G01N33/574
Abstract: The present invention is directed to a combination therapy involving an anti-HER2 antibody-drug conjugate and a selective Bcl-2 inhibitor for the treatment of a patient suffering from cancer, particularly, a HER2-expressing cancer.
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公开(公告)号：US09518118B2
公开(公告)日：2016-12-13
申请号：US14851001
申请日：2015-09-11
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/28 , A61K47/48 , C07K16/32 , A61K39/395 , G01N33/574
CPC classification number: C07K16/32 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K39/3955 , A61K47/68 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K47/6863 , A61K49/00 , C07K16/2863 , C07K16/3015 , C07K2317/24 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92 , G01N33/57415 , G01N33/57446 , G01N33/57492 , G01N2333/82
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗HER2抗体和免疫缀合物及其使用方法。
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公开(公告)号：US20200255539A1
公开(公告)日：2020-08-13
申请号：US16721525
申请日：2019-12-19
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , G01N33/574 , C07K16/30 , A61K49/00 , A61K31/704 , A61K31/675 , A61K31/5517 , C07K16/28 , A61K39/395 , A61K47/68
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20200085840A1
公开(公告)日：2020-03-19
申请号：US16391738
申请日：2019-04-23
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K31/5517 , A61K47/68 , A61K39/395 , C07K16/00 , C07K16/32
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US10314846B2
公开(公告)日：2019-06-11
申请号：US15438418
申请日：2017-02-21
Applicant: GENENTECH, INC.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K39/395 , A61K31/5517 , A61K47/68 , C07K16/00 , C07K16/32
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号：US20250121058A1
公开(公告)日：2025-04-17
申请号：US18984106
申请日：2024-12-17
Applicant: GENENTECH, INC.
Inventor： Gail Lewis Phillips , Deepak Sampath , Ingrid Wertz
IPC: A61K39/395 , A61K31/496 , A61K31/635 , A61K39/00 , A61K45/06 , A61K47/68 , A61P35/00 , C07K16/32 , G01N33/574
Abstract: The present invention is directed to a combination therapy involving an anti-HER2 antibody-drug conjugate and a selective Bcl-2 inhibitor for the treatment of a patient suffering from cancer, particularly, a HER2-expressing cancer.
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公开(公告)号：US10179820B2
公开(公告)日：2019-01-15
申请号：US15296454
申请日：2016-10-18
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , A61K39/395 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K49/00 , C07K16/30 , A61K47/68
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20170174782A1
公开(公告)日：2017-06-22
申请号：US15296454
申请日：2016-10-18
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , C07K16/30 , A61K31/675 , A61K31/704 , A61K31/5517 , G01N33/574 , A61K49/00
CPC classification number: C07K16/32 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K39/3955 , A61K47/68 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K47/6863 , A61K49/00 , C07K16/2863 , C07K16/3015 , C07K2317/24 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92 , G01N33/57415 , G01N33/57446 , G01N33/57492 , G01N2333/82
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20160096893A1
公开(公告)日：2016-04-07
申请号：US14851001
申请日：2015-09-11
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/28 , A61K39/395 , G01N33/574 , A61K47/48
CPC classification number: C07K16/32 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K39/3955 , A61K47/68 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K47/6863 , A61K49/00 , C07K16/2863 , C07K16/3015 , C07K2317/24 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92 , G01N33/57415 , G01N33/57446 , G01N33/57492 , G01N2333/82
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗HER2抗体和免疫缀合物及其使用方法。
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