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1.发明申请MICROORGANISMS HAVING L-TRYPTOPHAN PRODUCTIVITY AND A METHOD FOR PRODUCTION OF L-TRYPTOPHAN USING SAME (AS AMENDED) 有权具有L-酪氨酸生产力的微生物和使用它的L-酪氨酸生产方法（如修改）公开(公告)号：US20160153014A1
公开(公告)日：2016-06-02
申请号：US14784621
申请日：2014-04-16
发明人： Hyung Joon Kim , Ju No Jang , Kyung Rim Kim , Keun Cheol Lee , Young Bin Hwang , Hyeong Pyo Hong
CPC分类号： C12P13/227 , C12N9/1077 , C12Y204/02018 , Y02P20/52
摘要： The present invention relates to a microorganism of the genus Escherichia having enhanced L-tryptophan productivity, which has been modified to express yeast anthranilate phosphoribosyltransferase in order to be able to produce L-tryptophan at high concentration, and to a method for producing L-tryptophan, comprising a step of culturing the microorganism. The microorganism of the genus Escherichia can produce L-tryptophan, and thus can be advantageously used in the pharmaceutical industry and the feed industry, particularly for animal feed.
摘要翻译： 本发明涉及具有增强的L-色氨酸生产力的埃希氏菌属微生物，其已被修饰以表达酵母邻氨基苯甲酸酯磷酸核糖转移酶，以便能够产生高浓度的L-色氨酸，以及L-色氨酸的生产方法 包括培养微生物的步骤。 埃希氏菌属的微生物可产生L-色氨酸，因此可有利地用于制药工业和饲料工业，尤其用于动物饲料。
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2.发明申请Microorganism able to Produce L-Amino Acid, and Method for Producing L-Amino Acid by Using the Same 审中-公开能够生产L-氨基酸的微生物以及通过使用L-氨基酸生产L-氨基酸的方法公开(公告)号：US20150050703A1
公开(公告)日：2015-02-19
申请号：US14370500
申请日：2013-01-07
CPC分类号： C12P13/227 , C07K14/245 , C12N1/20 , C12N9/0053 , C12N9/0071 , C12P13/08 , C12Y114/11 , Y02P20/59
摘要： The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using same. More specifically, the present invention relates to: recombinant Escherichia coli which is more efficient in producing L-threonine or L-tryptophan by increasing the ability to produce ATP which is used as the most plentiful energy source in cells when producing L-threonine or L-tryptophan; and a method for producing L-threonine or L-tryptophan by using same.
摘要翻译： 本发明涉及能够产生L-苏氨酸或L-色氨酸的微生物，以及通过使用它们生产L-苏氨酸或L-色氨酸的方法。 更具体地说，本发明涉及：重组大肠杆菌，其通过增加产生L-苏氨酸或L的细胞中用作最丰富能量的ATP的能力而产生L-苏氨酸或L-色氨酸 色氨酸 以及通过使用它们生产L-苏氨酸或L-色氨酸的方法。
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公开(公告)号：US10815510B2
公开(公告)日：2020-10-27
申请号：US15321717
申请日：2015-06-23
发明人： Ki Yong Cheong , Kyung Rim Kim , Seok Myung Lee , Kwang Ho Lee , Keun Cheol Lee , Hyeong Pyo Hong
摘要： The present application relates to a microorganism of the genus Escherichia producing L-tryptophan and, more specifically, to a microorganism of the genus Escherichia with improved activity of producing L-tryptophan by weakening or inactivating the activity of endogenous 6-phosphogluconate dehydratase and 2-keto-3-deoxy-6-phosphogluconate aldolase.Additionally, the present application relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.
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4.发明授权Microorganisms having L-tryptophan productivity and a method for production of L-tryptophan using same 有权具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法公开(公告)号：US09562246B2
公开(公告)日：2017-02-07
申请号：US14784621
申请日：2014-04-16
发明人： Hyung Joon Kim , Ju No Jang , Kyung Rim Kim , Keun Cheol Lee , Young Bin Hwang , Hyeong Pyo Hong
CPC分类号： C12P13/227 , C12N9/1077 , C12Y204/02018 , Y02P20/52
摘要： The present invention relates to a microorganism of the genus Escherichia having enhanced L-tryptophan productivity, which has been modified to express yeast anthranilate phosphoribosyltransferase in order to be able to produce L-tryptophan at high concentration, and to a method for producing L-tryptophan, comprising a step of culturing the microorganism. The microorganism of the genus Escherichia can produce L-tryptophan, and thus can be advantageously used in the pharmaceutical industry and the feed industry, particularly for animal feed.
摘要翻译： 本发明涉及具有增强的L-色氨酸生产力的埃希氏菌属微生物，其已被修饰以表达酵母邻氨基苯甲酸酯磷酸核糖转移酶，以便能够产生高浓度的L-色氨酸，以及L-色氨酸的生产方法 包括培养微生物的步骤。 埃希氏菌属的微生物可产生L-色氨酸，因此可有利地用于制药工业和饲料工业，尤其用于动物饲料。
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公开(公告)号：US10787692B2
公开(公告)日：2020-09-29
申请号：US15465881
申请日：2017-03-22
IPC分类号： C12P13/22 , C12N9/02 , C07K14/245 , C12P13/08 , C12N1/20
摘要： The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using same. More specifically, the present invention relates to: recombinant Escherichia coli which is more efficient in producing L-threonine or L-tryptophan by increasing the ability to produce ATP which is used as the most plentiful energy source in cells when producing L-threonine or L-tryptophan; and a method for producing L-threonine or L-tryptophan by using same.
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公开(公告)号：US20170198317A1
公开(公告)日：2017-07-13
申请号：US15465881
申请日：2017-03-22
IPC分类号： C12P13/22 , C12N9/02 , C07K14/245 , C12N1/20 , C12P13/08
摘要： The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using same. More specifically, the present invention relates to: recombinant Escherichia coli which is more efficient in producing L-threonine or L-tryptophan by increasing the ability to produce ATP which is used as the most plentiful energy source in cells when producing L-threonine or L-tryptophan; and a method for producing L-threonine or L-tryptophan by using same.
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公开(公告)号：US10081822B2
公开(公告)日：2018-09-25
申请号：US15573236
申请日：2016-05-10
发明人： Seok Myung Lee , Baek Seok Lee , Kyungrim Kim , Kwang Ho Lee , Keun Cheol Lee , Hyeongpyo Hong
CPC分类号： C12P13/227 , C12N1/20 , C12N15/70 , C12P13/14
摘要： The present invention relates to a microorganism of the genus Escherichia in which L-tryptophan productivity is improved by inactivating phosphatase activity. Further, the present invention relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.
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公开(公告)号：US10053698B2
公开(公告)日：2018-08-21
申请号：US15112992
申请日：2014-04-25
发明人： Hyung Joon Kim , Su Yon Kwon , Eun Sung Koh , Ji Sun Lee , Keun Cheol Lee , Young Bin Hwang , Hyeong Pyo Hong
摘要： The present invention relates to an E. coli mutant strain having enhanced L-threonine productivity, which is obtained by introducing the permease of Corynebacterium origin, and to method of producing L-threonine using the E. coli mutant strain.
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公开(公告)号：US09758772B2
公开(公告)日：2017-09-12
申请号：US14899676
申请日：2014-04-24
发明人： Ji Sun Lee , Kwang Ho Lee , Eun Sung Koh , Hyung Joon Kim , Keun Cheol Lee , Young Bin Hwang
IPC分类号： C12P13/08 , C12P13/02 , C12N9/10 , C12N1/20 , C12P21/06 , C12P19/34 , C12N15/00 , C07H21/04 , C07K1/00 , C12N9/12 , C12N15/70 , C07K14/245
CPC分类号： C12N9/1247 , C07K14/245 , C12N15/70 , C12P13/08 , C12Y207/07006
摘要： The present application relates to an L-threonine-producing microorganism and a production method for L-threonine using the same, and more specifically, to a microorganism having enhanced L-threonine productivity and a method for producing L-threonine in high yield using the same.
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公开(公告)号：US10378032B2
公开(公告)日：2019-08-13
申请号：US15573244
申请日：2016-05-10
发明人： Hye Min Park , Baek Seok Lee , Seok Myung Lee , Kyungrim Kim , Kwang Ho Lee , Ki Yong Cheong , Keun Cheol Lee , Hyeongpyo Hong
摘要： The present disclosure relates to a microorganism of the genus Escherichia producing more L-tryptophan by inactivating the activity of phosphatase. Additionally, the present disclosure relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.
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