公开(公告)号：US11661616B2

公开(公告)日：2023-05-30

申请号：US16638974

申请日：2019-03-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ji Yeon Lee ,  Jin Sook Chang ,  Hyung Joon Kim ,  Byoung Hoon Yoon ,  Sun Hyoung Choi ,  Yunjung Choi

IPC: C12N9/10 ,  C12P13/04 ,  C12N9/14 ,  C12P13/14 ,  C12N15/77 ,  C12N1/20

CPC classification number: C12P13/04 ,  C12N1/20 ,  C12N9/1077 ,  C12N9/14 ,  C12N15/77 ,  C12P13/14 ,  C12Y204/02017 ,  C12Y306/01031 ,  C12N2830/55

Abstract: The present disclosure relates to a microorganism having increased glycine productivity and a method for producing a fermented composition using the microorganism, and more specifically, to a microorganism of the genus Corynebacterium having increased glycine productivity due to the introduction of a mutation in HisG, a method for preparing a fermented composition comprising glycine and glutamic acid using the microorganism of the genus Corynebacterium, and the fermented composition.

公开(公告)号：US20220387532A1

公开(公告)日：2022-12-08

申请号：US17773001

申请日：2020-09-18

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Cheol Woong Ha ,  Eun Bin Yang ,  Hyo Jin Kim ,  Hyung Joon Kim ,  Yeong Eun Im

IPC: A61K36/064 ,  A23K20/147 ,  A23L33/18 ,  A23L33/145 ,  A23K10/16 ,  A61K38/06 ,  A61K8/9728 ,  A61K8/64 ,  C12N1/18

Abstract: Provided are a novel yeast strain producing glutathione and a method of producing glutathione using the same.

公开(公告)号：US11104925B2

公开(公告)日：2021-08-31

申请号：US15741392

申请日：2016-06-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Peter Lee ,  Hyung Joon Kim ,  Hyang Choi ,  Song Gi Ryu ,  Sang Mok Lee

IPC: C12P13/08 ,  C12N15/77 ,  C07K14/34

Abstract: The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present disclosure relates to a microorganism of the genus Corynebacterium, which is modified such that the activity of a protein involved in cell wall hydrolysis is inactivated in comparison with the endogenous activity thereof; and a method for producing L-lysine using the same.

公开(公告)号：US10889843B2

公开(公告)日：2021-01-12

申请号：US15755582

申请日：2016-07-27

Applicant: CJ Cheiljedang Corporation

Inventor： Hyo Jeong Byun ,  Yoon Hee Chung ,  Hyung Joon Kim ,  Sun Young Lee ,  Hyun Koo Nam ,  Sun Mi Park ,  Sang Mok Lee

IPC: C12P13/08 ,  C12N1/21 ,  C12N15/77 ,  C07K14/34 ,  C12N9/10 ,  C12N9/12 ,  C12N9/02 ,  C12N9/88 ,  C12R1/15

Abstract: The present invention relates to an L-lysine-producing microorganism of the genus Corynebacterium and a method for producing L-lysine using the same.

公开(公告)号：US20180195097A1

公开(公告)日：2018-07-12

申请号：US15741392

申请日：2016-06-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Peter Lee ,  Hyung Joon Kim ,  Hyang Choi ,  Song Gi Ryu ,  Sang Mok Lee

IPC: C12P13/08 ,  C07K14/34 ,  C12N15/77

CPC classification number: C12P13/08 ,  C07K14/34 ,  C12N15/77

Abstract: The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present disclosure relates to a microorganism of the genus Corynebacterium, which is modified such that the activity of a protein involved in cell wall hydrolysis is inactivated in comparison with the endogenous activity thereof; and a method for producing L-lysine using the same.

公开(公告)号：US20160281070A1

公开(公告)日：2016-09-29

申请号：US14899676

申请日：2014-04-24

Applicant: CJ Cheiljedang Corporation

Inventor： Ji Sun Lee ,  Kwang Ho Lee ,  Eun Sung Koh ,  Hyung Joon Kim ,  Keun Cheol Lee ,  Young Bin Hwang

IPC: C12N9/12 ,  C12P13/08

CPC classification number: C12N9/1247 ,  C07K14/245 ,  C12N15/70 ,  C12P13/08 ,  C12Y207/07006

Abstract: The present application relates to an L-threonine-producing microorganism and a production method for L-threonine using the same, and more specifically, to a microorganism having enhanced L-threonine productivity and a method for producing L-threonine in high yield using the same.

Abstract translation: 本申请涉及L-苏氨酸生产微生物和使用其的L-苏氨酸的制备方法，更具体地说，涉及具有增强的L-苏氨酸生产力的微生物和使用该产物的高产率L-赖氨酸生产方法 相同。

公开(公告)号：US10208325B2

公开(公告)日：2019-02-19

申请号：US15309387

申请日：2015-05-08

Applicant: CJ Cheiljedang Corporation

Inventor： Peter Lee ,  Jun Ok Moon ,  Hyung Joon Kim ,  Song Gi Ryu

IPC: C12P13/08 ,  C07K14/34 ,  C12N9/16 ,  C12R1/15

Abstract: Provided are a microorganism of the genus Corynebacterium having an enhanced activity to produce L-lysine as a result of inactivating a secretory protein and a method for producing L-lysine using the microorganism.

公开(公告)号：US20180037615A1

公开(公告)日：2018-02-08

申请号：US15508662

申请日：2015-09-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Lan Huh ,  Kwang Ho Lee ,  Hyung Joon Kim ,  Jun Ok Moon ,  Song-Gi Ryu

IPC: C07K14/34 ,  C12R1/15 ,  C12P13/08

Abstract: The present disclosure relates to a novel modified RNA polymerase sigma factor A (SigA) polypeptide; a polynucleotide encoding the same; a microorganism containing the polypeptide; and a method for producing L-lysine using the microorganism.

公开(公告)号：US09556463B2

公开(公告)日：2017-01-31

申请号：US14514297

申请日：2014-10-14

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Un Hwan Ha ,  Yong Jae Kim ,  Jung Hoon Lee ,  Hee Sung Shin ,  Jun Ok Moon ,  Hyung Joon Kim ,  Kwang Ho Lee

IPC: C12N1/20 ,  C07K14/34 ,  C12P13/08 ,  C12N9/10 ,  C12N9/06

CPC classification number: C12P13/08 ,  C07K14/34 ,  C12N1/20 ,  C12N9/0014 ,  C12N9/1025 ,  C12Y104/99001

Abstract: The present invention relates to a novel isolated gene (polynucleotide) which encodes a protein having a biofilm formation inhibitory activity derived from Coryneform bacteria, a L-lysine-producing strain in which the polynucleotide is inactivated, and a method for producing L-lysine using the same.

Abstract translation: 本发明涉及编码具有衍生自棒状细菌的生物膜形成抑制活性的蛋白质的新型分离基因（多核苷酸），其中多核苷酸失活的L-赖氨酸生产菌株及其制备方法，使用 一样。

公开(公告)号：US20160153014A1

公开(公告)日：2016-06-02

申请号：US14784621

申请日：2014-04-16

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyung Joon Kim ,  Ju No Jang ,  Kyung Rim Kim ,  Keun Cheol Lee ,  Young Bin Hwang ,  Hyeong Pyo Hong

IPC: C12P13/22 ,  C12N9/10

CPC classification number: C12P13/227 ,  C12N9/1077 ,  C12Y204/02018 ,  Y02P20/52

Abstract: The present invention relates to a microorganism of the genus Escherichia having enhanced L-tryptophan productivity, which has been modified to express yeast anthranilate phosphoribosyltransferase in order to be able to produce L-tryptophan at high concentration, and to a method for producing L-tryptophan, comprising a step of culturing the microorganism. The microorganism of the genus Escherichia can produce L-tryptophan, and thus can be advantageously used in the pharmaceutical industry and the feed industry, particularly for animal feed.

Abstract translation: 本发明涉及具有增强的L-色氨酸生产力的埃希氏菌属微生物，其已被修饰以表达酵母邻氨基苯甲酸酯磷酸核糖转移酶，以便能够产生高浓度的L-色氨酸，以及L-色氨酸的生产方法 包括培养微生物的步骤。 埃希氏菌属的微生物可产生L-色氨酸，因此可有利地用于制药工业和饲料工业，尤其用于动物饲料。