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公开(公告)号：US20160272637A1
公开(公告)日：2016-09-22
申请号：US15032212
申请日：2014-10-28
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRASSBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Henrik TELLER , Eloisa JIMENEZ NUNEZ , Hartmut SCHIROK , Jürgen KLAR
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , A61K31/437 , C07D487/04
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
摘要翻译： 本发明涉及取代的氧代吡啶衍生物及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是心血管疾病，优选血栓形成或血栓栓塞性疾病，以及眼药水以及眼科疾病的药物的用途 。
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2.发明申请公开(公告)号：US20180086742A1
公开(公告)日：2018-03-29
申请号：US15786352
申请日：2017-10-17
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRASSBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Tom KINZEL , Henrik TELLER , Harmut SCHIROK , Jürgen KLAR , Eloisa Jimenez NUNEZ
IPC分类号： C07D405/06 , C07D213/84 , C07D213/85 , C07D401/12 , C07D413/14 , C07D413/12 , C07D417/12 , C07D213/64 , C07D213/69 , C07D409/06
CPC分类号： C07D405/06 , C07B2200/05 , C07D213/64 , C07D213/69 , C07D213/84 , C07D213/85 , C07D401/12 , C07D409/06 , C07D413/12 , C07D413/14 , C07D417/12
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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公开(公告)号：US20170298052A1
公开(公告)日：2017-10-19
申请号：US15513988
申请日：2015-09-22
发明人： Susanne RÖHRIG , Eloisa JIMENEZ NUNEZ , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Henrik TELLER , Alexander HILLISCH , Stefan HEITMEIER , Martina Victoria SCHMIDT , Jan STAMPFUß
IPC分类号： C07D413/06 , C07D401/06 , C07D213/69 , C07D405/06 , C07D213/64
CPC分类号： C07D413/06 , A61P7/10 , A61P27/02 , C07D213/64 , C07D213/69 , C07D213/85 , C07D401/06 , C07D401/12 , C07D405/06 , C07D413/12
摘要： The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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4.发明申请SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS 审中-公开取代的碘吡啶衍生物及其在治疗心血管疾病中的应用公开(公告)号：US20160368903A1
公开(公告)日：2016-12-22
申请号：US15256608
申请日：2016-09-04
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRASSBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Tom KINZEL , Henrik TELLER , Hartmut SCHIROK , Jürgen KLAR , Eloisa Jimenez NUNEZ
IPC分类号： C07D405/06
CPC分类号： C07D405/06 , C07B2200/05 , C07D213/64 , C07D213/69 , C07D213/84 , C07D213/85 , C07D401/12 , C07D409/06 , C07D413/12 , C07D413/14 , C07D417/12
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
摘要翻译： 本发明涉及取代的氧代吡啶衍生物及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是心血管疾病，优选血栓形成或血栓栓塞性疾病，以及眼药水以及眼科疾病的药物的用途 。
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公开(公告)号：US20230024752A1
公开(公告)日：2023-01-26
申请号：US17504243
申请日：2021-10-18
发明人： Eloisa JIMENEZ NUNEZ , Jens ACKERSTAFF , Susanne ROEHRIG , Alexander HILLISCH , Katharina MEIER , Stefan HEITMEIER , Adrian TERSTEEGEN , Jan STAMPFUSS , Pascal ELLERBROCK , Daniel MEIBOM , Dieter LANG
IPC分类号： C07D401/10 , C07D401/14 , C07D413/14 , C07D413/10 , A61P7/02
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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公开(公告)号：US20170283412A1
公开(公告)日：2017-10-05
申请号：US15513853
申请日：2015-09-22
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRAßBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Henrik TELLER , Eloisa JIMÉNEZ NÚNEZ , Hartmut SCHIROK , Jürgen KLAR , Mario LOBELL
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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公开(公告)号：US20160244437A1
公开(公告)日：2016-08-25
申请号：US15024923
申请日：2014-09-24
发明人： Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC分类号： C07D413/12 , C07D249/12 , C07D235/26 , C07D401/12 , C07D401/14 , C07D271/07 , C07D249/10 , C07D231/56 , C07D235/10 , C07D257/04 , C07D403/12
CPC分类号： C07D413/12 , C07D231/56 , C07D235/10 , C07D235/26 , C07D249/10 , C07D249/12 , C07D257/04 , C07D271/07 , C07D401/12 , C07D401/14 , C07D403/12
摘要： The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
摘要翻译： 本发明涉及取代的苯丙氨酸衍生物及其制备方法及其用于生产用于治疗和/或预防特别是心血管疾病和/或严重围手术期失血的疾病的药物的用途。
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公开(公告)号：US20160237067A1
公开(公告)日：2016-08-18
申请号：US15024327
申请日：2014-09-24
发明人： Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC分类号： C07D405/12 , C07D403/12 , C07D231/56 , C07D235/26 , C07D249/08 , C07D257/04 , C07D401/12
CPC分类号： C07D405/12 , C07D231/56 , C07D235/26 , C07D249/08 , C07D249/10 , C07D257/04 , C07D401/12 , C07D403/12
摘要： The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
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9.发明申请SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF AS FACTOR XIA/PLASMA 有权取代的碘吡啶衍生物及其作为因子XIA / PLASMA的用途公开(公告)号：US20160152613A1
公开(公告)日：2016-06-02
申请号：US14906771
申请日：2014-07-21
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRAßBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Anja BUCHMÜLLER , Christoph GERDES , Henrik TELLER , Martina SCHÄFER , Adrian TERSTEEGEN
IPC分类号： C07D471/04 , C07D215/227 , C07D413/12 , C07D401/12 , C07D221/04
CPC分类号： A61K31/438 , A61K31/437 , C07D215/227 , C07D221/04 , C07D401/12 , C07D413/12 , C07D471/04
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
摘要翻译： 本发明涉及取代的氧代吡啶衍生物及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是心血管疾病，优选血栓形成或血栓栓塞性疾病，以及眼药水以及眼科疾病的药物的用途 。
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10.发明申请Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders 有权取代的氧吡啶衍生物及其用途治疗心血管疾病公开(公告)号：US20160052884A1
公开(公告)日：2016-02-25
申请号：US14780925
申请日：2014-03-27
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRAßBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Tom KINZEL , Henrik TELLER , Hartmut SCHIROK , Jürgen KLAR , Eloisa JIMENEZ NUNEZ
IPC分类号： C07D213/64 , C07D413/12 , C07D213/84 , C07D409/06 , C07D405/06 , C07D413/14 , C07D417/12 , C07D401/12 , C07D213/69
CPC分类号： C07D405/06 , C07B2200/05 , C07D213/64 , C07D213/69 , C07D213/84 , C07D213/85 , C07D401/12 , C07D409/06 , C07D413/12 , C07D413/14 , C07D417/12
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
摘要翻译： 本发明涉及取代的氧代吡啶衍生物及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是心血管疾病，优选血栓形成或血栓栓塞性疾病，以及眼药水以及眼科疾病的药物的用途 。
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