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公开(公告)号:US20160244437A1
公开(公告)日:2016-08-25
申请号:US15024923
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D413/12 , C07D249/12 , C07D235/26 , C07D401/12 , C07D401/14 , C07D271/07 , C07D249/10 , C07D231/56 , C07D235/10 , C07D257/04 , C07D403/12
CPC classification number: C07D413/12 , C07D231/56 , C07D235/10 , C07D235/26 , C07D249/10 , C07D249/12 , C07D257/04 , C07D271/07 , C07D401/12 , C07D401/14 , C07D403/12
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
Abstract translation: 本发明涉及取代的苯丙氨酸衍生物及其制备方法及其用于生产用于治疗和/或预防特别是心血管疾病和/或严重围手术期失血的疾病的药物的用途。
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公开(公告)号:US20160237067A1
公开(公告)日:2016-08-18
申请号:US15024327
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D405/12 , C07D403/12 , C07D231/56 , C07D235/26 , C07D249/08 , C07D257/04 , C07D401/12
CPC classification number: C07D405/12 , C07D231/56 , C07D235/26 , C07D249/08 , C07D249/10 , C07D257/04 , C07D401/12 , C07D403/12
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
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公开(公告)号:US20160272617A1
公开(公告)日:2016-09-22
申请号:US15025030
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D401/12 , C07D257/04 , C07D231/56 , C07D403/12 , C07D451/04 , C07D487/04 , C07D413/12 , C07D263/58 , C07D235/26 , C07D249/04 , C07D235/08 , C07D209/42 , C07D249/08 , C07D401/14
CPC classification number: C07D401/12 , C07D209/42 , C07D231/56 , C07D235/08 , C07D235/26 , C07D249/04 , C07D249/08 , C07D249/10 , C07D257/04 , C07D263/58 , C07D401/14 , C07D403/12 , C07D413/12 , C07D417/12 , C07D451/04 , C07D487/04
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
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公开(公告)号:US20160237044A1
公开(公告)日:2016-08-18
申请号:US15024355
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D257/04 , C07D413/12 , C07D237/32 , C07D403/12 , C07D235/26 , C07D249/08 , C07D401/12 , C07D271/07
CPC classification number: C07D257/04 , C07B2200/07 , C07D231/56 , C07D235/26 , C07D237/32 , C07D249/08 , C07D249/10 , C07D271/07 , C07D401/12 , C07D403/12 , C07D413/12
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss. TRG416065
Abstract translation: 本发明涉及取代的苯丙氨酸衍生物及其制备方法及其用于生产用于治疗和/或预防特别是心血管疾病和/或严重围手术期失血的疾病的药物的用途。 TRG416065
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公开(公告)号:US20160222056A1
公开(公告)日:2016-08-04
申请号:US15024974
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07K5/065
CPC classification number: C07K5/06078 , C07D401/12 , C07D401/14 , C07D413/12 , C07D471/08 , C07D498/08
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
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公开(公告)号:US20160280699A1
公开(公告)日:2016-09-29
申请号:US15025009
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRAßBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D413/14 , C07D401/14 , C07D413/12 , C07D403/12 , C07D401/12
CPC classification number: C07D413/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D413/12
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
Abstract translation: 本发明涉及取代的苯丙氨酸衍生物及其制备方法及其用于生产用于治疗和/或预防特别是心血管疾病和/或严重围手术期失血的疾病的药物的用途。
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公开(公告)号:US20160280688A1
公开(公告)日:2016-09-29
申请号:US15024961
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D403/12 , C07D401/12 , C07D413/12 , C07D471/04
CPC classification number: C07D403/12 , C07D401/12 , C07D413/12 , C07D471/04
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
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公开(公告)号:US20160237045A1
公开(公告)日:2016-08-18
申请号:US15024939
申请日:2014-09-24
Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
Inventor: Ulrike RÖHN , Manuel ELLERMANN , Julia STRASSBURGER , Astrid WENDT , Susanne RÖHRIG , Robert Alan WEBSTER , Martina Victoria SCHMIDT , Adrian TERSTEEGEN , Kristin BEYER , Martina SCHÄFER , Anja BUCHMÜLLER , Christoph GERDES , Michael SPERZEL , Steffen SANDMANN , Stefan HEITMEIER , Alexander HILLISCH , Jens ACKERSTAFF , Carsten TERJUNG
IPC: C07D257/04 , C07D401/12 , C07D249/08 , C07D405/12
CPC classification number: C07D257/04 , C07D249/08 , C07D401/12 , C07D405/12 , C07D413/12
Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
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