公开(公告)号：US20220144848A1

公开(公告)日：2022-05-12

申请号：US17416274

申请日：2019-12-18

申请人： Bayer Aktiengesellschaft ,  Bayer Pharma Aktiengesellschaft

发明人： Susanne ROEHRIG ,  Sebastian ESSIG ,  Pascal ELLERBROCK ,  Sonja ANLAUF ,  Thomas NEUBAUER ,  Alexander HILLISCH ,  Katharina MEIER ,  Stefan HEITMEIER ,  Adrian TERSTEEGEN ,  Martina SCHAFER ,  Jan STAMPFUSS ,  Dieter LANG ,  Eloisa JIMENEZ NUNEZ ,  Jens ACKERSTAFF ,  Henrik TELLER ,  Zengqiang ZOU ,  Ping LIU ,  Xianghai MENG ,  Frank LESSMANN

IPC分类号： C07D491/044

摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.

公开(公告)号：US20200339567A1

公开(公告)日：2020-10-29

申请号：US16758751

申请日：2018-10-18

申请人： Bayer Aktiengesellschaft ,  Bayer Pharma Aktiengesellschaft

发明人： Daniel MEIBOM ,  Jutta MEYER ,  Karl COLLINS ,  Nuria ORTEGA HERNANDEZ ,  Jan STAMPFUSS ,  Frank WUNDER ,  Till FREUDENBERGER ,  Thomas MONDRITZKI ,  Nina Alexandra SCHEERER ,  Kirsten LEINEWEBER ,  Jens SCHAMBERGER ,  Alexander STRAUB ,  Kersten Matthias GERICKE ,  Walter KROH ,  Mario LOBELL ,  Klaus MÜNTER

IPC分类号： C07D471/04 ,  C07D519/00 ,  A61K31/444 ,  A61K45/06 ,  A61P9/10 ,  A61K31/437

摘要： The present application relates to novel substituted imidazopyridine amides of the formula (I), to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular, neurological and central nervous as well as metabolic disorders.

公开(公告)号：US20230024752A1

公开(公告)日：2023-01-26

申请号：US17504243

申请日：2021-10-18

申请人： Bayer Pharma Aktiengesellschaft

发明人： Eloisa JIMENEZ NUNEZ ,  Jens ACKERSTAFF ,  Susanne ROEHRIG ,  Alexander HILLISCH ,  Katharina MEIER ,  Stefan HEITMEIER ,  Adrian TERSTEEGEN ,  Jan STAMPFUSS ,  Pascal ELLERBROCK ,  Daniel MEIBOM ,  Dieter LANG

IPC分类号： C07D401/10 ,  C07D401/14 ,  C07D413/14 ,  C07D413/10 ,  A61P7/02

摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.