公开(公告)号：US20230024752A1

公开(公告)日：2023-01-26

申请号：US17504243

申请日：2021-10-18

申请人： Bayer Pharma Aktiengesellschaft

发明人： Eloisa JIMENEZ NUNEZ ,  Jens ACKERSTAFF ,  Susanne ROEHRIG ,  Alexander HILLISCH ,  Katharina MEIER ,  Stefan HEITMEIER ,  Adrian TERSTEEGEN ,  Jan STAMPFUSS ,  Pascal ELLERBROCK ,  Daniel MEIBOM ,  Dieter LANG

IPC分类号： C07D401/10 ,  C07D401/14 ,  C07D413/14 ,  C07D413/10 ,  A61P7/02

摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

公开(公告)号：US20180194745A1

公开(公告)日：2018-07-12

申请号：US15742063

申请日：2016-07-05

申请人： BAYER PHARMA AKTIENGESELLSCHAFT

发明人： Eloisa JIMENEZ NUNEZ ,  Jens ACKERSTAFF ,  Susanne RÖHRIG ,  Alexander HILLISCH ,  Katharina MEIER ,  Stefan HEITMEIER ,  Adrian TERSTEEGEN ,  Jan STAMPFUß ,  Pascal ELLERBROCK ,  Daniel MEIBOM ,  Dieter LANG

IPC分类号： C07D401/10 ,  C07D401/14 ,  C07D413/10 ,  C07D413/14 ,  A61P7/02

摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

公开(公告)号：US20220144848A1

公开(公告)日：2022-05-12

申请号：US17416274

申请日：2019-12-18

申请人： Bayer Aktiengesellschaft ,  Bayer Pharma Aktiengesellschaft

发明人： Susanne ROEHRIG ,  Sebastian ESSIG ,  Pascal ELLERBROCK ,  Sonja ANLAUF ,  Thomas NEUBAUER ,  Alexander HILLISCH ,  Katharina MEIER ,  Stefan HEITMEIER ,  Adrian TERSTEEGEN ,  Martina SCHAFER ,  Jan STAMPFUSS ,  Dieter LANG ,  Eloisa JIMENEZ NUNEZ ,  Jens ACKERSTAFF ,  Henrik TELLER ,  Zengqiang ZOU ,  Ping LIU ,  Xianghai MENG ,  Frank LESSMANN

IPC分类号： C07D491/044

摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.

公开(公告)号：US20180250280A1

公开(公告)日：2018-09-06

申请号：US15757135

申请日：2016-08-30

申请人： BAYER PHARMA AKTIENGESELLSCHAFT

发明人： Eloisa JIMENEZ NUNEZ ,  Jens ACKERSTAFF ,  Pascal ELLERBROCK ,  Alexander HILLISCH ,  Katharina MEIER ,  Stefan HEITMEIER ,  Adrian TERSTEEGEN ,  Jan STAMPFUß

IPC分类号： A61K31/4412 ,  A61K31/4433 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/444 ,  A61P1/00 ,  A61P7/02 ,  A61P27/02

CPC分类号： A61K31/4412 ,  A61K31/4433 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/444 ,  A61P1/00 ,  A61P7/02 ,  A61P27/02 ,  C07D213/69 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/06 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D413/14 ,  C07D487/04

摘要： The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.