专利检索 ap:("Acucela Inc.") AND inv:"Jennifer Gage" 第 1 页

1.

发明授权
Compounds for treating ophthalmic diseases and disorders 有权
标题翻译：用于治疗眼科疾病和病症的化合物

公开(公告)号：US09193669B2

公开(公告)日：2015-11-24

申请号：US14175959

申请日：2014-02-07

申请人： Acucela Inc.

发明人： Ian L. Scott , Vladimir A. Kuksa , Feng Hong , Ryo Kubota , Jennifer Gage

IPC分类号： C07C215/00 , C07C211/49 , A61K31/167 , A61K31/18 , C07B59/00 , C07C211/52 , C07C215/14 , C07C215/42 , C07C215/68 , C07C217/08 , C07C217/10 , C07C217/58 , C07C225/22 , C07C233/36 , C07C233/43 , C07C233/62 , C07C275/40 , C07C311/08 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/24 , C07C335/18 , C07D277/28 , C07C215/08 , C07C225/06 , C07C233/25

CPC分类号： C07C233/25 , A61K31/167 , A61K31/18 , C07B59/001 , C07B2200/05 , C07C211/49 , C07C211/52 , C07C215/08 , C07C215/14 , C07C215/42 , C07C215/68 , C07C217/08 , C07C217/10 , C07C217/58 , C07C225/06 , C07C225/22 , C07C233/36 , C07C233/43 , C07C233/62 , C07C275/40 , C07C311/08 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/24 , C07C335/18 , C07C2601/08 , C07C2601/14 , C07D277/28

摘要： Provided are compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

摘要翻译： 提供了化合物，其药物组合物，以及使用所述化合物和组合物治疗眼科疾病和病症如老年性黄斑变性和Stargardt氏病的方法。

2.

发明申请
Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders 有权

公开(公告)号：US20150166494A1

公开(公告)日：2015-06-18

申请号：US14630889

申请日：2015-02-25

申请人： Acucela Inc.

发明人： Ian Leslie Scott , Vladimir Aleksandrovich Kuska , Anna Gall , Mark W. Orme , Jennifer Gage , Thomas L. Little, JR. , Qin Jiang , Lana Michele Rossiter , Kevin F. McGee, JR. , Ryo Kubota

IPC分类号： C07D295/03 , C07C237/04 , C07C323/25 , C07C211/27

CPC分类号： A61K31/5375 , A61K31/137 , A61K31/145 , A61K31/167 , A61K31/40 , A61K31/4453 , A61K31/495 , C07C211/27 , C07C211/28 , C07C211/29 , C07C215/08 , C07C215/30 , C07C215/42 , C07C215/46 , C07C217/10 , C07C217/16 , C07C217/18 , C07C217/48 , C07C217/54 , C07C217/62 , C07C217/72 , C07C225/06 , C07C225/18 , C07C233/05 , C07C237/04 , C07C317/28 , C07C323/25 , C07C323/32 , C07C323/33 , C07C2602/14 , C07C2602/16 , C07D207/06 , C07D211/14 , C07D295/03

摘要： The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

3.

发明申请
COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS 有权
标题翻译：用于治疗眼睛疾病和疾病的化合物

公开(公告)号：US20140228443A1

公开(公告)日：2014-08-14

申请号：US14175959

申请日：2014-02-07

申请人： Acucela Inc.

发明人： Ian L. Scott , Vladimir A. Kuksa , Feng Hong , Ryo Kubota , Jennifer Gage

IPC分类号： C07C211/49 , C07C233/25 , C07C225/06 , C07C233/62 , C07C215/08

CPC分类号： C07C233/25 , A61K31/167 , A61K31/18 , C07B59/001 , C07B2200/05 , C07C211/49 , C07C211/52 , C07C215/08 , C07C215/14 , C07C215/42 , C07C215/68 , C07C217/08 , C07C217/10 , C07C217/58 , C07C225/06 , C07C225/22 , C07C233/36 , C07C233/43 , C07C233/62 , C07C275/40 , C07C311/08 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/24 , C07C335/18 , C07C2601/08 , C07C2601/14 , C07D277/28

摘要： Provided are compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

摘要翻译： 提供了化合物，其药物组合物，以及使用所述化合物和组合物治疗眼科疾病和病症如老年性黄斑变性和Stargardt氏病的方法。

4.

发明授权
Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders 有权

公开(公告)号：US09464033B2

公开(公告)日：2016-10-11

申请号：US14807436

申请日：2015-07-23

申请人： Acucela Inc.

发明人： Ian Leslie Scott , Vladimir Aleksandrovich Kuksa , Mark W. Orme , Thomas Little , Anna Gall , Jennifer Gage , Feng Hong

IPC分类号： C07C321/00 , C07C215/68 , C07D309/06 , C07D333/16 , C07C211/27 , C07C211/30 , C07C215/30 , C07C215/42 , C07C217/14 , C07C217/48 , C07C217/62 , C07C217/72 , C07C235/34 , C07C237/20 , C07C251/40 , C07C255/58 , C07C323/29 , C07C323/36 , C07D209/32 , C07D213/14 , C07D309/10 , C07D333/06 , C07D335/02 , C07C217/64 , C07D213/38 , C07D309/12 , C07C215/28 , C07C317/28 , C07C323/25

CPC分类号： C07C215/68 , C07C211/27 , C07C211/30 , C07C215/28 , C07C215/30 , C07C215/42 , C07C217/14 , C07C217/48 , C07C217/62 , C07C217/64 , C07C217/72 , C07C235/34 , C07C237/20 , C07C251/40 , C07C255/58 , C07C317/28 , C07C323/25 , C07C323/29 , C07C323/36 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D209/32 , C07D213/14 , C07D213/38 , C07D309/06 , C07D309/10 , C07D309/12 , C07D333/06 , C07D333/16 , C07D335/02

摘要： Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

5.

发明授权
Styrenyl derivative compounds for treating ophthalmic diseases and disorders 有权

公开(公告)号：US09421210B2

公开(公告)日：2016-08-23

申请号：US14630897

申请日：2015-02-25

申请人： Acucela Inc.

发明人： Ian Leslie Scott , Vladimir Aleksandrovich Kuska , Anna Gall , Mark W. Orme , Jennifer Gage , Thomas L. Little, Jr. , Qin Jiang , Lana Michele Rossiter , Kevin F. McGee, Jr. , Ryo Kubota

IPC分类号： C07C211/27 , C07C217/18 , A61K31/5375 , C07C211/28 , C07C211/29 , C07C215/08 , C07C215/30 , C07C215/42 , C07C215/46 , C07C217/16 , C07C217/48 , C07C217/54 , C07C217/62 , C07C217/72 , C07C225/18 , C07C233/05 , C07C237/04 , C07C317/28 , C07C323/25 , C07C323/32 , C07D295/03 , C07C225/06 , C07C323/33 , C07D207/06 , C07D211/14 , A61K31/137 , A61K31/145 , A61K31/167 , A61K31/40 , A61K31/4453 , A61K31/495

CPC分类号： A61K31/5375 , A61K31/137 , A61K31/145 , A61K31/167 , A61K31/40 , A61K31/4453 , A61K31/495 , C07C211/27 , C07C211/28 , C07C211/29 , C07C215/08 , C07C215/30 , C07C215/42 , C07C215/46 , C07C217/10 , C07C217/16 , C07C217/18 , C07C217/48 , C07C217/54 , C07C217/62 , C07C217/72 , C07C225/06 , C07C225/18 , C07C233/05 , C07C237/04 , C07C317/28 , C07C323/25 , C07C323/32 , C07C323/33 , C07C2602/14 , C07C2602/16 , C07D207/06 , C07D211/14 , C07D295/03

摘要： The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

6.

发明授权
Styrenyl derivative compounds for treating ophthalmic diseases and disorders 有权

公开(公告)号：US09314467B2

公开(公告)日：2016-04-19

申请号：US14630889

申请日：2015-02-25

申请人： Acucela Inc.

发明人： Ian Leslie Scott , Vladimir Aleksandrovich Kuska , Anna Gall , Mark W. Orme , Jennifer Gage , Thomas L. Little, Jr. , Qin Jiang , Lana Michele Rossiter , Kevin F. McGee, Jr. , Ryo Kubota

IPC分类号： C07C211/27 , A61K31/137 , A61K31/5375 , C07C211/28 , C07C211/29 , C07C215/08 , C07C215/30 , C07C215/42 , C07C215/46 , C07C217/16 , C07C217/48 , C07C217/54 , C07C217/62 , C07C217/72 , C07C225/18 , C07C233/05 , C07C237/04 , C07C317/28 , C07C323/25 , C07C323/32 , C07D295/03 , C07C217/10 , C07C225/06 , C07C323/33 , C07D207/06 , C07D211/14 , A61K31/145 , A61K31/167 , A61K31/40 , A61K31/4453 , A61K31/495

CPC分类号： A61K31/5375 , A61K31/137 , A61K31/145 , A61K31/167 , A61K31/40 , A61K31/4453 , A61K31/495 , C07C211/27 , C07C211/28 , C07C211/29 , C07C215/08 , C07C215/30 , C07C215/42 , C07C215/46 , C07C217/10 , C07C217/16 , C07C217/18 , C07C217/48 , C07C217/54 , C07C217/62 , C07C217/72 , C07C225/06 , C07C225/18 , C07C233/05 , C07C237/04 , C07C317/28 , C07C323/25 , C07C323/32 , C07C323/33 , C07C2602/14 , C07C2602/16 , C07D207/06 , C07D211/14 , C07D295/03

摘要： The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

7.

发明申请
STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS 审中-公开
标题翻译：用于治疗眼底疾病和疾病的苯乙烯衍生化合物

公开(公告)号：US20150238497A1

公开(公告)日：2015-08-27

申请号：US14631711

申请日：2015-02-25

申请人： Acucela Inc.

发明人： Ian Leslie Scott , Vladimir Aleksandrovich Kuksa , Anna Gall , Mark W. Orme , Jennifer Gage , Thomas L. Little, JR. , Qin Jiang , Lana Michele Rossiter , Kevin F. McGee, JR. , Ryo Kubota

IPC分类号： A61K31/5375 , A61K31/40 , A61K31/145 , A61K31/495 , A61K31/167 , A61K31/137 , A61K31/4453

CPC分类号： A61K31/5375 , A61K31/137 , A61K31/145 , A61K31/167 , A61K31/40 , A61K31/4453 , A61K31/495 , C07C211/27 , C07C211/28 , C07C211/29 , C07C215/08 , C07C215/30 , C07C215/42 , C07C215/46 , C07C217/10 , C07C217/16 , C07C217/18 , C07C217/48 , C07C217/54 , C07C217/62 , C07C217/72 , C07C225/06 , C07C225/18 , C07C233/05 , C07C237/04 , C07C317/28 , C07C323/25 , C07C323/32 , C07C323/33 , C07C2602/14 , C07C2602/16 , C07D207/06 , C07D211/14 , C07D295/03

摘要： The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

摘要翻译： 本发明一般涉及用于治疗神经变性疾病和病症，特别是眼科疾病和病症的组合物和方法。本文提供了苯乙烯衍生物化合物，包括但不限于二苯乙烯衍生物化合物，以及包含这些化合物的组合物，其可用于治疗和预防眼科疾病和病症，包括年龄相关性黄斑变性（AMD）和斯塔尔加氏病。