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    Systems and methods for transferring liquids
    2.
    发明授权
    Systems and methods for transferring liquids 有权

    公开(公告)号：US10761104B2

    公开(公告)日：2020-09-01

    申请号：US15593228

    申请日：2017-05-11

    Applicant: Agilent Technologies, Inc.

    Inventor： Reid A. Brennen ,  Bo Curry ,  Joel Myerson ,  Paige Anderson ,  Arthur Schleifer ,  Rolfe Anderson

    IPC: G01N35/00 ,  G01N35/10 ,  C12N15/10

    Abstract: One or more liquids are transferred from a source array to one or more remotely positioned destination sites such as chambers by utilizing one or more movable transfer elements, such as contact pins or capillaries. The source array may include a predetermined organization of addresses at which materials are positioned. One or more materials may be selected for transfer. Based on the selection, one or more addresses may be accessed by the transfer element(s). The addresses may correspond to spots on a surface of the source array. Each spot may be a feature containing one or more (bio)chemical compounds. At the chamber(s), the material(s) may be processed, such by reaction with one or more reagents. The reaction(s) may entail synthesis of one or more desired products. Alternatively, reaction(s) may be performed at the source array, and the product(s) then transferred to the chamber(s).

    SYSTEMS AND METHODS FOR TRANSFERRING LIQUIDS
    3.
    发明申请
    SYSTEMS AND METHODS FOR TRANSFERRING LIQUIDS 审中-公开

    公开(公告)号：US20170328928A1

    公开(公告)日：2017-11-16

    申请号：US15593228

    申请日：2017-05-11

    Applicant: Agilent Technologies, Inc.

    Inventor： Reid A. Brennen ,  Bo Curry ,  Joel Myerson ,  Paige Anderson ,  Arthur Schleifer ,  Rolfe Anderson

    IPC: G01N35/10 ,  G01N35/00 ,  C12N15/10

    CPC classification number: G01N35/1074 ,  G01N35/1009 ,  G01N35/1065 ,  G01N2035/1037 ,  G01N2035/1039 ,  G01N2035/1044

    Abstract: One or more liquids are transferred from a source array to one or more remotely positioned destination sites such as chambers by utilizing one or more movable transfer elements, such as contact pins or capillaries. The source array may include a predetermined organization of addresses at which materials are positioned. One or more materials may be selected for transfer. Based on the selection, one or more addresses may be accessed by the transfer element(s). The addresses may correspond to spots on a surface of the source array. Each spot may be a feature containing one or more (bio)chemical compounds. At the chamber(s), the material(s) may be processed, such by reaction with one or more reagents. The reaction(s) may entail synthesis of one or more desired products. Alternatively, reaction(s) may be performed at the source array, and the product(s) then transferred to the chamber(s).

    HIGH THROUGHPUT GENE ASSEMBLY IN DROPLETS
    8.
    发明申请
    HIGH THROUGHPUT GENE ASSEMBLY IN DROPLETS 审中-公开
    高渗透基因组装在DROPLETS

    公开(公告)号：US20150361422A1

    公开(公告)日：2015-12-17

    申请号：US14550713

    申请日：2014-11-21

    Applicant: Agilent Technologies, Inc.

    Inventor： Jeffrey R. Sampson ,  Nicholas M. Sampas ,  Joel Myerson ,  Paige Anderson ,  Bo Curry

    IPC: C12N15/10 ,  B01J19/00

    Abstract: Provided herein, among other things, is a method comprising: (a) obtaining a mixture of multiple sets of oligonucleotides, wherein the oligonucleotides within each set each comprise a terminal indexer sequence can be assembled to produce a synthon; and (b) hybridizing the oligonucleotide mixture to an array, thereby spatially-separating the different sets of oligonucleotides from one another. Other embodiments are also provided.

    Abstract translation: 本文提供了一种方法，其包括：（a）获得多组寡核苷酸的混合物，其中每组中的寡核苷酸各自包含末端分子序列可以组装以产生合成子; 和（b）将寡核苷酸混合物与阵列杂交，从而将不同组的寡核苷酸彼此空间分离。 还提供了其他实施例。

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