-
公开(公告)号:US20230288009A1
公开(公告)日:2023-09-14
申请号:US18018553
申请日:2021-07-29
申请人: UNIVERSITÄT ROSTOCK
发明人: JOHANNES BÜKER , ANDRÉ LASS
IPC分类号: F16L55/033 , F04B11/00 , F04D15/00 , F16L55/05
CPC分类号: F16L55/0333 , F04B11/00 , F04D15/0083 , F16L55/05 , F15B21/008
摘要: The invention relates to a device for active reduction of pressure fluctuations in a hydrodynamic system comprising a pump, a pressure fluctuation generator and at least one pressure sensor, and a controller unit. The controller unit is adapted to control the pressure fluctuation generator and to receive a pressure fluctuation signal from the pressure sensor. Furthermore, the present invention relates to a corresponding method and a pressure fluctuation generator for a corresponding device.
-
公开(公告)号:US11179407B2
公开(公告)日:2021-11-23
申请号:US15779745
申请日:2016-11-30
申请人: Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften , Universität Rostock , Ruhr-Universität Bochum
发明人: Marcus Peters , Otto Holst , Christian Vogel , Alice Voss
IPC分类号: A61K31/7028 , A61K47/64 , A61P37/08 , A61P29/00 , A61K9/00 , A61K35/744 , A61K35/745 , C07H15/04
摘要: The present invention relates to L-arabino-oligosaccharides, in particular synthetically produced L-arabino-oligosaccharides and their uses for the prophylaxis of allergic reactions in mammals.
-
公开(公告)号:US20190028911A1
公开(公告)日:2019-01-24
申请号:US16060569
申请日:2016-12-08
申请人: UNIVERSITÄT ROSTOCK
发明人: Till WOLLENBERG
摘要: Devices and methods generate at least one database suitable for identifying problems in a wireless network. The devices and methods comprise at least one receiver unit for receiving data packets via a radio channel of the wireless network and a memory unit for storing data from received data packets. The devices and methods also comprise a control unit designed to store only control data contained in the received data packets in the memory unit. Thereby, the control unit is designed to dynamically select data packets received independently from the receiver unit for storage in the database.
-
公开(公告)号:US11714093B2
公开(公告)日:2023-08-01
申请号:US16631756
申请日:2018-07-16
申请人: Universität Rostock
发明人: Gustav Steinhoff , Julia Nesteruk , Markus Wolfien
CPC分类号: G01N33/6893 , C12Q1/686 , G01N33/5094 , G01N33/53 , G01N33/74 , C12Q1/6883 , G01N33/5005 , G01N2333/475 , G01N2333/50 , G01N2333/505 , G01N2333/535 , G01N2333/58 , G01N2333/78 , G01N2800/323 , G01N2800/324 , G01N2800/325 , G01N2800/52 , G01N2800/60 , G16B40/00
摘要: The present invention relates to a method for prediction of response to cardiovascular regeneration comprising the use of biomarkers. Further, the present invention relates to a combination of the biomarkers for use in a method for prediction of response to cardiovascular regeneration, a computer device to perform a method according to the present invention and a device adapted for carrying out the inventive method.
-
公开(公告)号:US20200174020A1
公开(公告)日:2020-06-04
申请号:US16631756
申请日:2018-07-16
发明人: Gustav STEINHOFF , Julia NESTERUK , Markus WOLFIEN
IPC分类号: G01N33/68 , G16B40/00 , G01N33/50 , C12Q1/6883
摘要: The present invention relates to a method for prediction of response to cardiovascular regeneration comprising the use of biomarkers. Further, the present invention relates to a combination of the biomarkers for use in a method for prediction of response to cardiovascular regeneration, a computer device to perform a method according to the present invention and a device adapted for carrying out the inventive method.
-
公开(公告)号:US10260948B2
公开(公告)日:2019-04-16
申请号:US14648010
申请日:2013-11-26
发明人: Josef Hoeffner
摘要: The invention relates to a device (1) and a method (20) for determining a spectrum (X) of scattered radiation (S). The invention further relates to a method (70) for calculating the spectrum (X) and a method for compressing unstructured data (60) of known distribution. To be able to determine the spectrum (X) as precisely as possible and to derive from this the characteristics of materials that scatter laser pulses (P), the invention proposes that at least one characteristic of the laser pulse (P) is determined and that a spectrum analyzer (5) is used for this. Frequencies (F) of laser pulses (P) and volumes (M) of backscattered radiation (S) are combined into frequency and volume values (F′, M′) to calculate the spectrum (X). The most frequent data values are deleted from the data to compress the data (60).
-
公开(公告)号:US09238607B1
公开(公告)日:2016-01-19
申请号:US14600424
申请日:2015-01-20
发明人: Matthias Beller , Ralf Jackstell , X. Fang
IPC分类号: C07C45/50
CPC分类号: C07C45/505 , C07B41/06 , C07C45/49 , C07C201/12 , C07C221/00 , C07C253/30 , C07C2601/14 , C07D213/48 , C07D307/46 , C07D333/22 , C07F7/1804 , C07C47/21 , C07C47/24 , C07C47/232 , C07C47/277 , C07C47/238 , C07C255/56 , C07C205/44 , C07C223/02
摘要: The invention concerns a process for the catalytic production of unsaturated aldehydes by reacting an olefin in the presence of carbon monoxide and hydrogen, a rhodium compound and organic phosphorus-containing ligands in an organic solvent as well as a co-catalyst formed from a weak organic acid and an organic amine.
摘要翻译: 本发明涉及一种通过在一氧化碳和氢气存在下使烯烃与有机溶剂中的铑化合物和有机含磷配体反应生成不饱和醛的方法,以及由弱有机物形成的助催化剂 酸和有机胺。
-
公开(公告)号:US12018303B2
公开(公告)日:2024-06-25
申请号:US16764476
申请日:2018-11-16
申请人: ENZYMICALS AG , UNIVERSITÄT ROSTOCK
IPC分类号: C12P13/00 , C07C57/30 , C07C211/63 , C12P7/40
CPC分类号: C12P13/005 , C07C57/30 , C07C211/63 , C12P7/40
摘要: Described herein is a method for preparing an amino salt compound, the method including: i) providing a carbonyl compound; ii) reacting the carbonyl compound provided according to (i) in the presence of a transaminase with ii-a) at least one primary amine; and ii-b) at least one carboxylic acid; thereby obtaining a mixture including an at least partially crystallized amino salt compound including a cation and a carboxylate anion based on the at least one carboxylic acid added according to (ii-b). Also described herein is an amino salt compound obtained or obtainable by the method and to the amino salt compound, and a composition including a) an amine of general formula (IIa); and b) at least one carboxylic acid of general formula (III).
-
公开(公告)号:US20210371929A1
公开(公告)日:2021-12-02
申请号:US17284357
申请日:2019-10-11
申请人: UNIVERSITÄT ROSTOCK
发明人: Gustav STEINHOFF , Markus WOLFIEN
IPC分类号: C12Q1/6883 , G16B40/00 , G16B25/10 , G06N20/00 , G16H20/40
摘要: The present invention relates to a method for prediction of response to disease therapy, in particular to tissue regeneration, preferably to cardiovascular regeneration, comprising the use of a biomarker. Further, the present invention relates to a combination of biomarkers for use in a method for prediction of response to disease therapy, in particular to tissue regeneration, preferably to cardiovascular regeneration, a computer device to perform a method according to the present invention and a device adapted for carrying out the inventive method.
-
10.
公开(公告)号:US20210290956A1
公开(公告)日:2021-09-23
申请号:US17260309
申请日:2019-07-17
申请人: Universität Rostock
发明人: Robert David , Christian Rimmbach , Julia Jung
摘要: The present invention relates to a bioelectronic system comprising at least i) in vitro generated cardiac pacemaker tissue comprising cardiac pacemaker cells; ii) an electronic circuit applied to a semiconductor carrier and comprising at least one field-effect transistor; wherein the in vitro generated cardiac pacemaker tissue comprising cardiac pacemaker cells according to i) is immobilized on the electronic circuit according to ii) applied to the semiconductor carrier and is arranged in conductive communication with the at least one field-effect transistor. The invention also relates to a rate-adaptive cardiac pacemaker system comprising at least one rate-adaptive cardiac pacemaker, comprising at least one sensor unit, wherein the sensor unit is set up to detect at least one electrical cardiac signal; at least one pulse generator, wherein the pulse generator is set up to generate at least one electrical pacemaker pulse and to deliver it to the heart of a patient; at least one control unit, wherein the control unit is electrically connected to the sensor unit and the pulse generator; a bioelectronic system, wherein the bioelectronic system is conductively connected or connectable to the rate-adaptive cardiac pacemaker, in particular to the control unit.
-
-
-
-
-
-
-
-
-