专利检索 ap:("ENZYMICALS AG" OR "UNIVERSITÄT ROSTOCK") AND inv:"Philipp Süss" 第 1 页

1.

发明授权
Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation 有权

公开(公告)号：US12018303B2

公开(公告)日：2024-06-25

申请号：US16764476

申请日：2018-11-16

申请人： ENZYMICALS AG , UNIVERSITÄT ROSTOCK

发明人： Jan Von Langermann , Dennis Hülsewede , Marco Cornelius , Ulf Menyes , Philipp Süss

IPC分类号： C12P13/00 , C07C57/30 , C07C211/63 , C12P7/40

CPC分类号： C12P13/005 , C07C57/30 , C07C211/63 , C12P7/40

摘要： Described herein is a method for preparing an amino salt compound, the method including: i) providing a carbonyl compound; ii) reacting the carbonyl compound provided according to (i) in the presence of a transaminase with ii-a) at least one primary amine; and ii-b) at least one carboxylic acid; thereby obtaining a mixture including an at least partially crystallized amino salt compound including a cation and a carboxylate anion based on the at least one carboxylic acid added according to (ii-b). Also described herein is an amino salt compound obtained or obtainable by the method and to the amino salt compound, and a composition including a) an amine of general formula (IIa); and b) at least one carboxylic acid of general formula (III).