摘要:
A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.
摘要:
A method of manufacturing a drug delivery system uses gas cluster ion beam irradiation on an outer surface of a member to determine one or more characteristics of the drug delivery system.
摘要:
A method of controlling the drug release rate of a drug coated endovascular stent by depositing a drug material layer on the stent and then modifying the drug material using gas cluster ion beam irradiation to create a carbon matrix with interstices containing the original drug. The rate at which the drug elutes through the interstices can be controlled by processing parameters. Multiple layers may be employed to create time varying release rates.
摘要:
A method of controlling the drug release rate of a drug coated endovascular stent by depositing a drug material layer on the stent and then modifying the drug material using gas cluster ion beam irradiation to create a carbon matrix with interstices containing the original drug. The rate at which the drug elutes through the interstices can be controlled by processing parameters. Multiple layers may be employed to create time varying release rates.
摘要:
A testing kit and method for determining the day of ovulation in a woman who has menstruated having a plurality of test assemblies each with an upper chamber, a lower chamber in fluid communication with the upper chamber separated from the upper chamber by a screen member, a saliva-absorbable chewable plug which when chewed by the user can be compressed against the screen member to express saliva into the lower chamber which contains a reagent which produces a color change, the intensity of which is proportional to the concentration of glucose in the saliva wherein a plurality of such test assemblies are utilized one on each of successive days for determination of the peak color intensity on the day that the saliva has the greatest concentration of glucose to allow for computation from this peak day of the date of ovulation of the woman.
摘要:
A method of modifying the surface of a medical device to release a drug in a controlled way by providing a barrier layer on the surface of one or more drug coatings. The barrier layer consists of modified drug material converted to a barrier layer by irradiation by an accelerated neutral beam derived from an accelerated gas cluster ion beam. Also medical devices formed thereby.
摘要:
A method of controlling the drug release rate of a drug coated endovascular stent by depositing a drug material layer on the stent and then modifying the drug material using gas cluster ion beam irradiation to create a carbon matrix with interstices containing the original drug. The rate at which the drug elutes through the interstices can be controlled by processing parameters. Multiple layers may be employed to create time varying release rates.
摘要:
Methods of implanting, applying, or adhering various drug molecules directly into or onto the surface of medical devices through gas cluster ion beam (GCIB) and/or monomer ion beam surface modification of the medical devices before or after depositing the various drug molecules onto the medical devices.
摘要:
A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.
摘要:
In one embodiment, a drug delivery system and method provide a member including a combination of a drug substance and a polymer or other material, and an encapsulating layer formed in an outer surface of the member by gas cluster ion beam irradiation of the outer surface of the member, which encapsulating layer is adapted to determine one or more characteristics of the drug delivery system.