-
公开(公告)号：US20130282136A1
公开(公告)日：2013-10-24
申请号：US13922787
申请日：2013-06-20
申请人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
发明人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
IPC分类号： A61L27/54
CPC分类号： A61F2/28 , A61F2002/2817 , A61F2002/2835 , A61F2310/00359 , A61F2310/00976 , A61L27/3608 , A61L27/54 , A61L2300/414 , A61L2430/02
摘要： A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.
-
公开(公告)号：US20170290960A1
公开(公告)日：2017-10-12
申请号：US15624381
申请日：2017-06-15
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/602 , A61L2300/606 , A61L2420/02 , B05D1/02 , B05D3/068
摘要： A method of modifying the surface of a medical device to release a drug in a controlled way by providing a barrier layer on the surface of one or more drug coatings. The barrier layer consists of modified drug material converted to a barrier layer by irradiation by an accelerated neutral beam derived from an accelerated gas cluster ion beam. Also medical devices formed thereby.
-
公开(公告)号：US09808344B2
公开(公告)日：2017-11-07
申请号：US14833402
申请日：2015-08-24
申请人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
发明人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
CPC分类号： A61F2/28 , A61F2002/2817 , A61F2002/2835 , A61F2310/00359 , A61F2310/00976 , A61L27/3608 , A61L27/54 , A61L2300/414 , A61L2430/02
摘要： A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.
-
公开(公告)号：US10342900B2
公开(公告)日：2019-07-09
申请号：US13591837
申请日：2012-08-22
IPC分类号： A61L31/16 , A61L27/54 , A61K31/436
摘要： A method of modifying the surface of a medical device to release a drug in a controlled way by providing a barrier layer on the surface of one or more drug coatings. The barrier layer consists of modified drug material converted to a barrier layer by irradiation by an accelerated neutral beam derived from an accelerated gas cluster ion beam. Also medical devices formed thereby.
-
公开(公告)号：US20180090295A1
公开(公告)日：2018-03-29
申请号：US15826445
申请日：2017-11-29
IPC分类号： H01J37/05 , H05H3/02 , H01J37/317 , H01J37/147
CPC分类号： H01J37/05 , H01J37/147 , H01J37/317 , H01J37/3171 , H01J2237/0041 , H01J2237/0812 , H01J2237/15 , H05H1/20 , H05H3/02 , Y10T428/24355 , Y10T428/24479 , Y10T428/30
摘要： An apparatus and method provided a drug layer formed on a surface region of a medical device, the drug layer comprised of a drug deposition and a carbonized or densified layer formed from the drug deposition by irradiation on an outer surface of the drug deposition, wherein the carbonized or densified layer does not penetrate through the drug deposition and is adapted to release drug from the drug deposition at a predetermined rate.
-
6.发明申请公开(公告)号：US20150359636A1
公开(公告)日：2015-12-17
申请号：US14833402
申请日：2015-08-24
申请人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
发明人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
IPC分类号： A61F2/28
CPC分类号： A61F2/28 , A61F2002/2817 , A61F2002/2835 , A61F2310/00359 , A61F2310/00976 , A61L27/3608 , A61L27/54 , A61L2300/414 , A61L2430/02
摘要： A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.
摘要翻译： 制备用于植入的预成型骨形状的方法通过由GCIB得到的中性束和照射预先形成的骨形状，照射预先形成的骨形状的至少一部分。
-
7.发明授权公开(公告)号：US09114195B2
公开(公告)日：2015-08-25
申请号：US13922787
申请日：2013-06-20
申请人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
发明人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga , Stephen M. Blinn
CPC分类号： A61F2/28 , A61F2002/2817 , A61F2002/2835 , A61F2310/00359 , A61F2310/00976 , A61L27/3608 , A61L27/54 , A61L2300/414 , A61L2430/02
摘要： A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.
摘要翻译： 制备用于植入的预成型骨形状的方法通过由GCIB得到的中性束和照射预先形成的骨形状，照射预先形成的骨形状的至少一部分。
-
公开(公告)号：US20150125510A1
公开(公告)日：2015-05-07
申请号：US14238868
申请日：2012-08-22
IPC分类号： A61L31/16 , A61L27/54 , A61K31/436
CPC分类号： A61L31/16 , A61K31/436 , A61L27/54 , A61L2300/602 , A61L2300/606 , A61L2300/61 , A61L2400/18 , A61L2420/02
摘要： A method of modifying the surface of a medical device to release a drug in a controlled way by providing a barrier layer on the surface of one or more drug coatings. The barrier layer consists of modified drug material converted to a barrier layer by irradiation by an accelerated neutral beam derived from an accelerated gas cluster ion beam. Also medical devices formed thereby.
摘要翻译： 一种通过在一种或多种药物涂层的表面上提供阻挡层来改变医疗装置的表面以以受控方式释放药物的方法。 阻挡层由经加速的气体簇离子束衍生的加速中性束照射而被转换成阻挡层的改性药物材料组成。 还由此形成的医疗装置。
-
公开(公告)号：US20150024020A1
公开(公告)日：2015-01-22
申请号：US14238364
申请日：2012-08-22
CPC分类号： A61L31/16 , A61L27/303 , A61L27/34 , A61L27/54 , A61L31/08 , A61L31/084 , A61L31/10 , A61L2300/606 , A61L2300/62 , A61L2420/02 , A61L2420/08 , B05D3/00 , B05D3/068 , B05D7/56
摘要： An apparatus and method provides a drug layer formed on a surface region of a medical device, the drug layer comprised of a drug deposition and a carbonized or densified layer formed from the drug deposition by irradiation on an outer surface of the drug deposition, wherein the carbonized or densified layer does not penetrate through the drug deposition and is adapted to release drug from the drug deposition at a predetermined rate.
摘要翻译： 一种装置和方法提供了形成在医疗装置的表面区域上的药物层，所述药物层由药物沉积组成，所述药物层由药物沉积的外表面上的药物沉积形成的碳化或致密化层形成，其中， 碳化或致密化层不穿透药物沉积，并且适于以预定速率从药物沉积中释放药物。
-
公开(公告)号：US20130218264A1
公开(公告)日：2013-08-22
申请号：US13591837
申请日：2012-08-22
CPC分类号： A61L31/16 , A61K31/436 , A61L27/54 , A61L2300/602 , A61L2300/606 , A61L2300/61 , A61L2400/18 , A61L2420/02
摘要： A method of modifying the surface of a medical device to release a drug in a controlled way by providing a barrier layer on the surface of one or more drug coatings. The barrier layer consists of modified drug material converted to a barrier layer by irradiation by an accelerated neutral beam derived from an accelerated gas cluster ion beam. Also medical devices formed thereby.
-
-
-
-
-
-
-
-
-
搜索结果
26 条记录 (耗时 0.041 秒)
