-
公开(公告)号:US20250033964A1
公开(公告)日:2025-01-30
申请号:US18225191
申请日:2023-07-24
Applicant: Research Triangle Institute
Inventor: Shaojun James Zhou , Raghubir P. Gupta , John Reeves Carpenter, III , Brian S. Turk
Abstract: Synthesis gas containing nitrogen as the majority component is processed to increase the hydrogen to carbon dioxide ratio. Nitrogen, carbon dioxide, and other contaminants are subsequently removed by a purification unit to produce a purified hydrogen gas stream. A recycle stream within the purification unit helps achieve a hydrogen purity greater than 99.9 percent, and hydrogen recovery greater than 99 percent.
-
公开(公告)号:US12194205B2
公开(公告)日:2025-01-14
申请号:US17245529
申请日:2021-04-30
Applicant: Research Triangle Institute
Inventor: James Lynn Davis , Howard Jerome Walls , Karmann C. Mills , David Edward Dausch
Abstract: An air filtration media with integrated disinfection capability. The media has a collection filter for capture of pathogens, and an ultraviolet (UV) radiation source integrated into the collection filter such that the pathogens collected by the collection filter are exposed to UV radiation from the UV radiation source.
-
3.
公开(公告)号:US20240342683A1
公开(公告)日:2024-10-17
申请号:US18632596
申请日:2024-04-11
Applicant: Research Triangle Institute
Inventor: Ignacio LUZ MINGUEZ , Mustapha SOUKRI , Marty LAIL , Lora Goon TOY
CPC classification number: B01J20/226 , B01D53/02 , B01D53/228 , B01J20/28026 , B01J20/28033 , B01J20/28059 , B01J20/28061 , B01J20/28064 , B01J20/28066 , B01J20/28083 , B01D2253/204
Abstract: A suspension comprises a nano-crystalline metal organic framework suspended in a polymeric solution. The nano-crystalline metal organic framework comprises micropores having an average diameter in the range of 0.5-5 nm, and the nano-crystalline metal organic framework is substantially homogenously dispersed in the polymeric solution, which comprises a first polymeric material dissolved in a non-aqueous solvent.
-
公开(公告)号:US20240174605A1
公开(公告)日:2024-05-30
申请号:US18279985
申请日:2022-03-01
Applicant: RESEARCH TRIANGLE INSTITUTE
Inventor: Yanan ZHANG , Dehui ZHANG
IPC: C07C311/37 , A61K31/167 , A61K31/18 , A61K31/381 , A61K31/40 , A61K31/426 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4439 , A61K31/444 , A61K31/4453 , A61K31/4545 , A61K31/496 , A61P25/28 , C07C237/42 , C07D213/40 , C07D213/75 , C07D213/76 , C07D213/81 , C07D213/82 , C07D277/56 , C07D295/16 , C07D333/38 , C07D401/12 , C07D417/12
CPC classification number: C07C311/37 , A61K31/167 , A61K31/18 , A61K31/381 , A61K31/40 , A61K31/426 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4439 , A61K31/444 , A61K31/4453 , A61K31/4545 , A61K31/496 , A61P25/28 , C07C237/42 , C07D213/40 , C07D213/75 , C07D213/76 , C07D213/81 , C07D213/82 , C07D277/56 , C07D295/16 , C07D333/38 , C07D401/12 , C07D417/12 , C07C2601/02
Abstract: The present disclosure provides novel arylsulfonamide compounds as embodiments of the present disclosure. The compounds are believed to be orexin receptor agonists, useful for the treatment of diseases and conditions caused by reduced activity of orexin.
-
公开(公告)号:US20230339863A1
公开(公告)日:2023-10-26
申请号:US17796419
申请日:2021-01-29
Applicant: RESEARCH TRIANGLE INSTITUTE
Inventor: George AMATO , Rangan MAITRA , Scott P. RUNYON
IPC: C07D231/56
CPC classification number: C07D231/56
Abstract: The present disclosure includes peripheral partial agonists of one or more CB receptors, including modulation of CB1, both with and without CB2 selectivity. The compounds of the present disclosure may be useful in the treatment of diseases and disorders mediated by a CB-signaling pathway, including but not limited to pain, gastrointestinal disorders, metabolic disorders, and liver disorders, such as alcoholic steatohepatitis or nonalcoholic steatohepatitis (NASH).
-
公开(公告)号:US11767225B2
公开(公告)日:2023-09-26
申请号:US16324296
申请日:2017-08-10
Applicant: Research Triangle Institute
Inventor: Ignacio Luz Minguez , Mustapha Soukri , Marty Lail
CPC classification number: C01B39/026 , B01J20/103 , B01J20/226 , B01J20/3236 , B01J20/3265 , B01J29/06 , B01J31/1691 , C01B39/00 , C01B39/02 , C01B39/48 , B01D2253/108 , B01D2253/204 , B01D2259/4583
Abstract: A method, comprising i) contacting an aqueous solution of an organic ligand salt of the formula AX(L−X) with a mesoporous material (MPM) to form an impregnated mesoporous salt material of the formula AX(L−X)/MPM, ii) treating the impregnated mesoporous salt material with an aqueous acidic solution to form an impregnated mesoporous acid material of the formula HX(L−X)/MPM, iii) contacting an aqueous solution of a metal precursor of the formula M+y(B)y with the impregnated mesoporous acid material to form an impregnated mesoporous metal organic framework precursor of the formula [M+y(B)y][Hx(L−x)]/MPM, and iv) at least one of 1) heating the impregnated mesoporous metal organic framework precursor in the absence of a solvent or 2) exposing the impregnated mesoporous metal organic framework precursor to a volatile vapor in the absence of a solvent such that the heating or the exposing forms a hybrid material of the formula (M+yL−x)/MPM, wherein the hybrid material comprises a nano-crystalline metal organic framework (MOF) embedded within the mesoporous material.
-
公开(公告)号:US11724938B2
公开(公告)日:2023-08-15
申请号:US16652318
申请日:2018-09-24
Applicant: Research Triangle Institute
Inventor: Shaojun James Zhou , Raghubir P. Gupta , John Reeves Carpenter , Brian S. Turk
CPC classification number: C01B3/56 , C01B3/366 , C01B3/48 , C01B3/501 , C01B2203/0255 , C01B2203/0283 , C01B2203/043 , C01B2203/0405 , C01B2203/0475 , C01B2203/1241 , C01B2203/146 , C01B2203/148
Abstract: Synthesis gas containing nitrogen as the majority component is processed to increase the hydrogen to carbon dioxide ratio. Nitrogen, carbon dioxide, and other contaminants are subsequently removed by a purification unit to produce a purified hydrogen gas stream. A recycle stream within the purification unit helps achieve a hydrogen purity greater than 99.9 percent, and hydrogen recovery greater than 99 percent.
-
公开(公告)号:US11648202B2
公开(公告)日:2023-05-16
申请号:US16650965
申请日:2018-10-11
Applicant: Research Triangle Institute
Inventor: Elliott Richard Pauli , Hemant N. Joshi , Anvit S. Vasavada
IPC: A61K9/16 , A61K9/48 , A61K31/4706
CPC classification number: A61K9/1652 , A61K9/1658 , A61K9/4816 , A61K9/4866 , A61K31/4706
Abstract: Water-dispersible pharmaceutical compositions of hydroxychloroquine sulfate in powder or granule form are provided that allow for ease of preparation of measured-dose, liquid suspensions that are palatable and suitable for pediatric administration. The compositions in granular or powder form are efficiently dissolvable in water and can be provided encapsulated within a two-piece releasable hard capsule or a packet or pouch for easy release. An ion-pairing agent is present in the formulation of the composition that masks the bitter taste of the hydroxychloroquine sulfate, significantly reducing the need for addition of a sweetening agent. Methods are provided for preparing the water-dispersible pharmaceutical compositions of hydroxychloroquine sulfate and for preparing palatable weight-based pediatric doses.
-
公开(公告)号:US20230070155A1
公开(公告)日:2023-03-09
申请号:US17798188
申请日:2021-02-19
Applicant: Research Triangle Institute
Inventor: Ninell Mortensen , Leah Johnson , Jeffrey Brent Mecham
Abstract: Provided by the inventive concept or nanoplastic or microplastic particles, reference standard materials including nanoplastic or microplastic particles, methods of using, and methods of preparing the same. Uses of the nanoplastic and/or microplastic particles of the inventive concept include tracking of nanoplastic and/or microplastic particle dispersion/distribution in environmental and/or biological systems, as well as in organisms that are within the environment.
-
公开(公告)号:US20230069918A1
公开(公告)日:2023-03-09
申请号:US17795476
申请日:2021-01-26
Applicant: Research Triangle Institute
Inventor: Leah Marie Johnson , Nicolas Daniel Huffman , Jeffrey Brent Mecham , Ian Edward Stewart , Natalie Marie Girouard
IPC: C08G59/50
Abstract: The present disclosure relates to delivery and release compositions, systems, and methods of use thereof. In particular, the present disclosure relates to degradable polymeric systems including a first epoxy-containing monomer and a second, different epoxy-containing monomer, wherein the degradable polymeric system is crosslinked, and wherein one of the first epoxy-containing monomer and the second, different epoxy-containing monomer includes one or more ester groups; delivery systems incorporating degradable polymeric systems; and methods for providing cargo to a petroleum reservoir.
-
-
-
-
-
-
-
-
-