摘要:
The disclosure relates to a biological analysis device including: means for circulating a fluid to be analyzed, comprising a fluidic chamber, optical detection means based on a semiconductor, including a detection front face, a rear face and pads of electrical contacts located on this rear face.
摘要:
The present invention relates to an operating device characterized in that it comprises an active surface that is substantially non-wetting with respect to a liquid of interest; at least one zone for the localized capture of a drop of said liquid formed on said active surface; at least one operating zone arranged with a capture zone in such a way that the operating zone is at least partially covered by the drop of the liquid when said drop is captured by said capture zone; and means for leaving a drop of said liquid on said capture zone. This device makes it possible in particular to form high-density arrays of drops of said liquid on a surface, with the aim in particular of carrying out chemical and/or biochemical reactions and/or of analysing the liquid of interest in each drop. It finds, for example, an application in biological chips.
摘要:
A method for dividing an analyte present in a solution and that is fixed on magnetic particles, and devices to be used in the method and systems for implementing the method. The method includes sedimentation of the magnetic particles together with separation into a plurality of residues. One implementation: forms at least a residue of magnetic particles in a first receptacle; and displaces the at least the residues towards a plurality of second receptacles, preferably by relative translation of a magnetic system. The second receptacle is connected to the first receptacle through a fluid channel.
摘要:
A positioning system for an optical microstructure (64) in a devise (6) operating under the action of a control means includes a flexible element (63) supporting the optical microstructure and connected to the device. The orientation of the flexible element with respect to the device can be varied under the action of control means in order to put the optical microstructure (64) into at least one determined position. The flexible element is immobilized with respect to the device in order to hold the optical microstructure (64) in the determined position when the control means no longer act.
摘要:
The method for controlling the progression of a fluid, from upstream to downstream, in a microfluidic component comprising for example a plurality of microchannels each comprising a plurality of successive reaction or detection zones and a plurality of passive valves, controls the progression of the fluid in the microchannels by controlling the increase of a pressure difference between upstream and downstream of the component. The method controls the pressure difference increase discontinuously in the form of enabling pulses so as in particular to synchronize passing of the corresponding passive valves of the microchannels. The pressure difference is advantageously adjusted to a zero value between two successive enabling pulses.
摘要:
The invention relates to a device for taking blood by capillarity and incorporating a filter and downstream therefrom, an absorbent material for separating a plasma phase of the blood from a cell phase. The device is characterized in that the filter comprises in succession: a prefilter (6) for spreading the blood over the surface of a first membrane (2) having pores of dimension lying in the range 0.1 μm to 5 μm, said membrane having no clumping agent; and said first membrane (2).
摘要:
The method for controlling the progression of a fluid, from upstream to downstream, in a microfluidic component comprising for example a plurality of microchannels each comprising a plurality of successive reaction or detection zones and a plurality of passive valves, controls the progression of the fluid in the microchannels by controlling the increase of a pressure difference between upstream and downstream of the component. The method controls the pressure difference increase discontinuously in the form of enabling pulses so as in particular to synchronize passing of the corresponding passive valves of the microchannels. The pressure difference is advantageously adjusted to a zero value between two successive enabling pulses.
摘要:
A device and process for the amplification of fluorescence emitted by an areal sample. The device includes a support transmitting all or part of a fluorescence signal and configured to support the areal sample and a thin layer interposed between the support and the areal sample. The thin layer has a refractive index greater than the refractive index of the support and than the refractive index of a medium flooding the areal sample during a fluorescence measurement. The thickness of the thin layer is chosen so that the thin layer transmits all or part of the fluorescence signal which is measured after passing through the support.
摘要:
A micromonochromator is formed on a substrate and includes a diffraction device (6) associated with an entry that includes at least one entry point and an exit that includes at least one exit point. A mobile arrangement of light guidance (2-20, 4-26) is associated with the entry or the exit or both, and a recovery device (23) is provided by the exit. The mobile arrangement includes at least one mobile beam integrated in the substrate and equipped with at least one light guide. The mobile beam is able to sweep the entry and/or exit in a continuous manner.
摘要:
This device comprises a planar input area (4), a planar output area (6), a microguides array (2) laid out between these areas, means (8) of inputting a light beam associated with the input area and means (10) of outputting a light beam associated with the output area. According to the invention, at least two pieces (12, 16, 22) are formed, one comprising one part of at least one of the areas and the corresponding associated means, the other comprising the other part of this area and the other components of the device, and the pieces are added on so as to form the complete device and to adjust the wave length of this device. Application to optical telecommunications and optical spectrometry.