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公开(公告)号：US20130296695A1
公开(公告)日：2013-11-07
申请号：US13939161
申请日：2013-07-10
申请人： Maegan K. SPENCER , Christopher B. WHITE , Charles W. MCNALL , Dennis W. JACKSON , Michael ZUNG , Nicholas J. SPINELLI , Benjamin NGO , Evangeline LUMABAS , Kin F. CHAN , John F. BLACK , Michael H. ROSENTHAL , John B. SIMPSON
发明人： Maegan K. SPENCER , Christopher B. WHITE , Charles W. MCNALL , Dennis W. JACKSON , Michael ZUNG , Nicholas J. SPINELLI , Benjamin NGO , Evangeline LUMABAS , Kin F. CHAN , John F. BLACK , Michael H. ROSENTHAL , John B. SIMPSON
IPC分类号： A61B5/00
摘要： A system for imaging a body lumen includes a controller and a display. The controller is configured to connect to a proximal end of a catheter having an optical fiber extending along the length of an elongate catheter body. The controller is further configured to rotate a distal end of the optical fiber from a location near a proximal end of the elongate catheter body, acquire optical coherence tomography (OCT) images using the optical fiber as the distal end of the optical fiber rotates, and determine a rotational lag of the distal end of the optical fiber. The display is configured to display one or more OCT images corrected for the rotational lag.
摘要翻译： 用于对体腔成像的系统包括控制器和显示器。 控制器被配置为连接到具有沿着细长导管主体的长度延伸的光纤的导管的近端。 所述控制器进一步构造成从所述细长导管主体的近端附近的位置旋转所述光纤的远端，当所述光纤的远端旋转时，使用所述光纤采集光学相干断层摄影（OCT）图像;以及 确定光纤远端的旋转滞后。 显示器被配置为显示针对旋转滞后校正的一个或多个OCT图像。
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公开(公告)号：US20170238808A1
公开(公告)日：2017-08-24
申请号：US15434758
申请日：2017-02-16
申请人： John B. SIMPSON , Himanshu N. PATEL , Michael ZUNG , Charles W. MCNALL , Priyanshu GUPTA , Maegan K. SPENCER , Christopher B. WHITE , Dennis W. JACKSON , John F. BLACK
发明人： John B. SIMPSON , Himanshu N. PATEL , Michael ZUNG , Charles W. MCNALL , Priyanshu GUPTA , Maegan K. SPENCER , Christopher B. WHITE , Dennis W. JACKSON , John F. BLACK
CPC分类号： A61B5/0084 , A61B5/0035 , A61B5/0062 , A61B5/0066 , A61B5/02007 , A61B5/4836 , A61B5/6852 , A61B6/12 , A61B6/485 , A61B6/487 , A61B8/0841 , A61B17/32002 , A61B17/320758 , A61B90/37 , A61B90/39 , A61B2017/00057 , A61B2017/003 , A61B2017/00778 , A61B2017/22068 , A61B2090/306 , A61B2090/3614 , A61B2090/3735 , A61B2090/376 , A61B2090/3966 , A61B2090/3983 , A61B2217/007 , A61B2562/0233 , F04C2270/0421
摘要： A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.
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3.发明申请OCCLUSION-CROSSING DEVICES, ATHERECTOMY DEVICES, AND IMAGING 审中-公开OCCLUSION-CROSSING DEVICES，ATHERECTOMY DEVICES，AND IMAGING公开(公告)号：US20160262839A1
公开(公告)日：2016-09-15
申请号：US15162353
申请日：2016-05-23
IPC分类号： A61B34/20 , A61B17/00 , A61B17/3207
CPC分类号： A61B34/20 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B6/12 , A61B6/487 , A61B17/00234 , A61B17/320725 , A61B17/320758 , A61B90/37 , A61B90/39 , A61B2017/00296 , A61B2017/22068 , A61B2034/2055 , A61B2034/2065 , A61B2090/306 , A61B2090/3614 , A61B2090/3735 , A61B2217/007 , A61B2562/0233
摘要： Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.
摘要翻译： 本文描述了用于产生和识别指示血管内斑块的特征（“新月形”）区域的方法，以及适于利用该特征区域的系统和装置。
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4.发明申请公开(公告)号：US20160262791A1
公开(公告)日：2016-09-15
申请号：US15162330
申请日：2016-05-23
申请人： Himanshu N. PATEL , John B. SIMPSON , Charles W. McNALL , Maegan K. SPENCER , Michael ZUNG , Priyanshu GUPTA
发明人： Himanshu N. PATEL , John B. SIMPSON , Charles W. McNALL , Maegan K. SPENCER , Michael ZUNG , Priyanshu GUPTA
IPC分类号： A61B17/3207
CPC分类号： A61B17/320783 , A61B1/00165 , A61B1/00179 , A61B1/00183 , A61B1/3137 , A61B5/0066 , A61B17/320725 , A61B17/320758 , A61B90/37 , A61B2017/00292 , A61B2017/320791 , A61B2090/3614 , A61B2090/3735
摘要： Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.
摘要翻译： 这里描述了动脉粥样硬化切除术导管，系统和方法，其包括在导管的远端驱动一个或多个切割器的致动的可纵向移位的驱动轴。 本文所述的导管可以包括用于在切割组织之前，期间或之后成像的一个或多个成像传感器。 在一些变型中，成像传感器可以围绕导管的周边旋转，而与切割器的旋转无关。 这里还描述了可以在没有切割器的情况下使用的成像导管。
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公开(公告)号：US09125562B2
公开(公告)日：2015-09-08
申请号：US12829267
申请日：2010-07-01
申请人： Maegan K. Spencer , Christopher B. White , Charles W. McNall , Dennis W. Jackson , Michael Zung , Nicholas J. Spinelli , Benjamin Ngo , Evangeline Lumabas , Kin F. Chan , John F. Black , Michael H. Rosenthal , John B. Simpson
发明人： Maegan K. Spencer , Christopher B. White , Charles W. McNall , Dennis W. Jackson , Michael Zung , Nicholas J. Spinelli , Benjamin Ngo , Evangeline Lumabas , Kin F. Chan , John F. Black , Michael H. Rosenthal , John B. Simpson
CPC分类号： A61B5/0066 , A61B5/0062 , A61B5/0073 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B5/7257
摘要： Catheter-based Optical Coherence Tomography (OCT) systems utilizing an optical fiber that is positioned off-axis of the central longitudinal axis of the catheter have many advantage over catheter-based OCT systems, particularly those having centrally-positioned optical fibers or fibers that rotate independently of the elongate body of the catheter. An OCT system having an off-axis optical fiber for visualizing the inside of a body lumen may be rotated with the body of the elongate catheter, relative to a handle portion. The handle may include a fiber management pathway for the optical fiber that permits the off-axis optical fiber to rotate with the catheter body relative to the handle. The system may also include optical processing elements adapted to prepare and process the OCT image collected by the off-axis catheter systems described herein.
摘要翻译： 使用位于导管的中心纵向轴线离轴的光纤的基于导管的光学相干断层扫描（OCT）系统具有优于基于导管的OCT系统的许多优点，特别是具有中心定位的光纤或旋转的光纤 独立于导管的细长主体。 具有用于可视化体腔内部的离轴光纤的OCT系统可以相对于手柄部分与细长导管的主体一起旋转。 手柄可以包括用于光纤的光纤管理路径，其允许离轴光纤相对于手柄与导管主体一起旋转。 该系统还可以包括适于制备和处理由本文所述的离轴导管系统收集的OCT图像的光学处理元件。
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6.发明申请OCCLUSION-CROSSING DEVICES, ATHERECTOMY DEVICES, AND IMAGING 有权OCCLUSION-CROSSING DEVICES，ATHERECTOMY DEVICES，AND IMAGING公开(公告)号：US20130123615A1
公开(公告)日：2013-05-16
申请号：US13675867
申请日：2012-11-13
IPC分类号： A61B5/00 , A61B17/3207
CPC分类号： A61B34/20 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B6/12 , A61B6/487 , A61B17/00234 , A61B17/320725 , A61B17/320758 , A61B90/37 , A61B90/39 , A61B2017/00296 , A61B2017/22068 , A61B2034/2055 , A61B2034/2065 , A61B2090/306 , A61B2090/3614 , A61B2090/3735 , A61B2217/007 , A61B2562/0233
摘要： Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.
摘要翻译： 这里描述的是用于产生和识别指示血管内的粥样斑块切除斑块的特征（“新月形”）区域的方法，以及适于利用该特征区域的系统和装置。
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公开(公告)号：US20110021926A1
公开(公告)日：2011-01-27
申请号：US12829267
申请日：2010-07-01
申请人： Maegan K. SPENCER , Christopher B. White , Charles W. McNall , Dennis W. Jackson , Michael Zung , Nicholas J. Spinelli , Benjamin Ngo , Evangeline Lumabas , Kin F. Chan , John F. Black , Michael H. Rosenthal , John B. Simpson
发明人： Maegan K. SPENCER , Christopher B. White , Charles W. McNall , Dennis W. Jackson , Michael Zung , Nicholas J. Spinelli , Benjamin Ngo , Evangeline Lumabas , Kin F. Chan , John F. Black , Michael H. Rosenthal , John B. Simpson
IPC分类号： A61B6/00
CPC分类号： A61B5/0066 , A61B5/0062 , A61B5/0073 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B5/7257
摘要： Catheter-based Optical Coherence Tomography (OCT) systems utilizing an optical fiber that is positioned off-axis of the central longitudinal axis of the catheter have many advantage over catheter-based OCT systems, particularly those having centrally-positioned optical fibers or fibers that rotate independently of the elongate body of the catheter. An OCT system having an off-axis optical fiber for visualizing the inside of a body lumen may be rotated with the body of the elongate catheter, relative to a handle portion. The handle may include a fiber management pathway for the optical fiber that permits the off-axis optical fiber to rotate with the catheter body relative to the handle. The system may also include optical processing elements adapted to prepare and process the OCT image collected by the off-axis catheter systems described herein.
摘要翻译： 使用位于导管的中心纵向轴线离轴的光纤的基于导管的光学相干断层扫描（OCT）系统具有优于基于导管的OCT系统的许多优点，特别是具有中心定位的光纤或旋转的光纤 独立于导管的细长主体。 具有用于可视化体腔内部的离轴光纤的OCT系统可以相对于手柄部分与细长导管的主体一起旋转。 手柄可以包括用于光纤的光纤管理路径，其允许离轴光纤相对于手柄与导管主体一起旋转。 该系统还可以包括适于制备和处理由本文所述的离轴导管系统收集的OCT图像的光学处理元件。
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公开(公告)号：US20180049700A1
公开(公告)日：2018-02-22
申请号：US15783800
申请日：2017-10-13
申请人： John F. BLACK , Maegan K. SPENCER , Michael ZUNG , Charles W. MCNALL , Evangeline LUMABAS , Michael H. ROSENTHAL , John B. SIMPSON
发明人： John F. BLACK , Maegan K. SPENCER , Michael ZUNG , Charles W. MCNALL , Evangeline LUMABAS , Michael H. ROSENTHAL , John B. SIMPSON
IPC分类号： A61B5/00
CPC分类号： A61B5/6852 , A61B5/0066
摘要： Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.
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公开(公告)号：US08644913B2
公开(公告)日：2014-02-04
申请号：US13433049
申请日：2012-03-28
申请人： John B. Simpson , Himanshu N. Patel , Michael Zung , Charles W. McNall , Priyanshu Gupta , Maegan K. Spencer , Christopher B. White , Dennis W. Jackson , John F. Black
发明人： John B. Simpson , Himanshu N. Patel , Michael Zung , Charles W. McNall , Priyanshu Gupta , Maegan K. Spencer , Christopher B. White , Dennis W. Jackson , John F. Black
CPC分类号： A61B5/0084 , A61B5/0035 , A61B5/0062 , A61B5/0066 , A61B5/02007 , A61B5/4836 , A61B5/6852 , A61B6/12 , A61B6/485 , A61B6/487 , A61B8/0841 , A61B17/32002 , A61B17/320758 , A61B90/37 , A61B90/39 , A61B2017/00057 , A61B2017/003 , A61B2017/00778 , A61B2017/22068 , A61B2090/306 , A61B2090/3614 , A61B2090/3735 , A61B2090/376 , A61B2090/3966 , A61B2090/3983 , A61B2217/007 , A61B2562/0233 , F04C2270/0421
摘要： The present invention relates to: (1) guidewire support/placement catheters; (2) support/placement catheters with imaging; (3) atherectomy catheters, (4) atherectomy catheters with imaging, (5) occlusion crossing catheters, and (6) occlusion crossing catheters with imaging as well as methods for using them to treat disorders (and particularly peripheral artery disease) and systems including them.
摘要翻译： 本发明涉及：（1）导丝支撑/放置导管; （2）成像辅助/放置导管; （3）粥样斑块切除术导管，（4）具有成像的粥样斑块切除导管，（5）闭塞导管，（6）具有成像的闭塞导管以及使用它们治疗疾病（特别是外周动脉疾病）和系统的方法，包括 他们。
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10.发明申请公开(公告)号：US20120046679A1
公开(公告)日：2012-02-23
申请号：US13175232
申请日：2011-07-01
IPC分类号： A61B17/22
CPC分类号： A61B17/320783 , A61B1/00165 , A61B1/00179 , A61B1/00183 , A61B1/3137 , A61B5/0066 , A61B17/320725 , A61B17/320758 , A61B90/37 , A61B2017/00292 , A61B2017/320791 , A61B2090/3614 , A61B2090/3735
摘要： Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.
摘要翻译： 这里描述了动脉粥样硬化切除术导管，系统和方法，其包括在导管的远端驱动一个或多个切割器的致动的可纵向移位的驱动轴。 本文所述的导管可以包括用于在切割组织之前，期间或之后成像的一个或多个成像传感器。 在一些变型中，成像传感器可以围绕导管的周边旋转，而与切割器的旋转无关。 这里还描述了可以在没有切割器的情况下使用的成像导管。
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