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    Ferromagnetic valves
    4.
    发明授权
    Ferromagnetic valves 有权

    公开(公告)号：US10039670B2

    公开(公告)日：2018-08-07

    申请号：US14423635

    申请日：2013-08-30

    Applicant: Massachusetts Eye & Ear Infirmary

    Inventor： Eleftherios Paschalis Ilios ,  Claes H. Dohlman

    IPC: A61M5/00 ,  A61F9/007 ,  A61M39/22 ,  F16K99/00

    Abstract: The disclosure includes devices and methods for controlling fluid flow. The devices include a tube configured to receive fluid from a fluid source; and a valve for controlling fluid flow through the tube, the valve responsive to fluid pressure in the tube. The valve includes a first magnet outside the tube at a fixed first distance from the tube and a second magnet outside the tube substantially opposite the first magnet and at a second distance from the tube, the second distance greater than the first distance. The valve includes a ferromagnetic fluid within the tube between the first magnet and the second magnet and held in position by a magnetic field generated by the first magnet. The amount of ferromagnetic fluid is sufficient to seal the tube when the fluid pressure is below a threshold pressure set by the second distance between the second magnet and the tube.

    VESTIBULAR TESTING
    9.
    发明申请
    VESTIBULAR TESTING 审中-公开
    VESTIBULAR测试

    公开(公告)号：US20160029945A1

    公开(公告)日：2016-02-04

    申请号：US14775421

    申请日：2014-03-12

    Applicant: Massachusetts Eye & Ear Infirmary

    Inventor： Daniel Michael Merfeld ,  Yongwoo Yi

    IPC: A61B5/00 ,  A61B5/16 ,  A61B3/10

    CPC classification number: A61B5/4023 ,  A61B3/10 ,  A61B5/1121 ,  A61B5/16 ,  A61B5/164 ,  A61B5/7246 ,  A61B5/7275 ,  A63G31/04 ,  A63G31/06 ,  A63G31/16

    Abstract: In one aspect, the disclosure features methods for estimating a vestibular function of a subject. The methods include moving the subject along a first direction parallel to the direction of gravity, receiving a first input set from the subject, the first input set indicating the subject's perception of the first direction, and estimating a first parameter related to a first vestibular function of the subject based on the first input. The methods further includes changing an orientation of the subject with respect to the earth, moving the subject along a second direction after changing the orientation of the subject, and receiving a second input set from the subject, the second input set indicating the subject's perception of the second direction.

    Abstract translation: 一方面，本发明的特征在于估计受试者的前庭功能的方法。 所述方法包括沿着与重力方向平行的第一方向移动受试者，从对象接收第一输入集合，第一输入集合指示受检者对第一方向的感知，以及估计与第一前庭功能相关的第一参数 的主题基于第一个输入。 所述方法还包括改变对象相对于地球的方位，在改变对象的方向之后沿着第二方向移动对象，以及从对象接收第二输入集合，第二输入集合指示被摄体的感知 第二个方向。

    METHODS OF DELIVERING PHARMACEUTICAL AGENTS
    10.
    发明申请
    METHODS OF DELIVERING PHARMACEUTICAL AGENTS 有权

    公开(公告)号：US20150283071A1

    公开(公告)日：2015-10-08

    申请号：US14739872

    申请日：2015-06-15

    Applicant: Massachusetts Eye & Ear Infirmary

    Inventor： Benjamin S. Bleier

    IPC: A61K9/00 ,  A61M31/00 ,  A61K31/473 ,  A61K38/18 ,  A61K47/36 ,  A61K47/38

    CPC classification number: A61K9/0085 ,  A61K31/137 ,  A61K31/473 ,  A61K31/485 ,  A61K38/18 ,  A61K38/185 ,  A61K47/36 ,  A61K47/38 ,  A61M31/00

    Abstract: Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include administering at least one pharmaceutical agent onto a SEM graft in the skull base of the subject. Also provided are methods of treating a neurological disorder or pain in a subject that include forming a SEM graft in the skull base of the subject and administering at least one pharmaceutical agent onto the SEM graft in the skull base of the subject. Also provided are methods of forming a SEM graft in the skull base of a subject, compositions for administration onto a SEM graft in the skull base or into an endonasal reservoir or endonasal reservoir device in a subject, and devices for administering such compositions onto a SEM graft in the skull base of a subject.

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