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公开(公告)号：US20130071882A1
公开(公告)日：2013-03-21
申请号：US13462612
申请日：2012-05-02
Applicant: Libing WANG , Chuanlai Xu , Liguang Xu , Xiaoling Wu
Inventor： Libing WANG , Chuanlai Xu , Liguang Xu , Xiaoling Wu
CPC classification number: C12P19/34 , B82Y20/00 , C07H21/04 , Y10S977/773 , Y10S977/885
Abstract: Multiple properties of plasmonic assemblies are determined by their geometrical organization. This patent focuses on the formation of Janus structure of the asymmetric assembly structure of the gold nanorods and gold nanoparticles. Chiral structure of gold nanorods and gold nanoparticles can be obtained through the characterization of optical spectra of the Janus structure. And it opens the door for the explanation of the mechanism of the chirality, plays a strong guiding role in the negative refractive material above and has good application prospects.
Abstract translation: 等离子体组件的多个性质由其几何组织决定。 该专利着重于金纳米棒和金纳米粒子的非对称组装结构的Janus结构的形成。 金纳米棒和金纳米颗粒的手性结构可以通过对Janus结构的光谱进行表征而获得。 它为手性机制的解释打开了大门，在上述负折射材料中起着很强的引导作用，具有良好的应用前景。
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2.发明申请VERSATILE ELECTROCHEMICAL PAPER-IMMUNOSENSOR AND METHOD FOR DETECTION OF AMINOGLYCOSIDE ANTIBIOTICS BY USING THE SENSOR 有权多种电化学纸 - 免疫荧光检测器和使用传感器检测氨基酰胺抗生素的方法公开(公告)号：US20120325681A1
公开(公告)日：2012-12-27
申请号：US13304496
申请日：2011-11-25
Applicant: Chuanlai Xu , Libing Wang , Xiaoling Wu , Hua Kuang , Wei Chen , Wei Ma
Inventor： Chuanlai Xu , Libing Wang , Xiaoling Wu , Hua Kuang , Wei Chen , Wei Ma
IPC: G01N27/327 , G01N33/53 , B82Y30/00 , B82Y5/00
CPC classification number: B82Y30/00 , G01N33/5308 , G01N33/5438 , G01N33/551
Abstract: An electrochemical paper-immunosensor and method for detecting aminoglycoside antibiotics is developed in the present invention. Single-walled carbon nanotubes are coated on the common filtration paper by dip-dry cycles. With antibody against neomycin adding to the coating solution, a high sensitive biosensor for specific detection of neomycin is prepared, satisfying to the rigid authority regulations. The sensor is not only sensitive but also rapid, comparing with the classic ELISA method, with LOD of 0.04 ng mL−1 and the whole detection process lasting less than 30 min. Another notable advantage of this invention is the versatility of the sensor, similar method is engaged to prepare the versatile sensor for other aminoglycoside antibiotics, replacement with relevant antibodies.
Abstract translation: 在本发明中开发了一种用于检测氨基糖苷类抗生素的电化学纸免疫传感器和方法。 单壁碳纳米管通过浸渍 - 干燥循环涂布在普通的滤纸上。 用新霉素抗体加入涂层溶液中，制备了一种用于特异性检测新霉素的高灵敏度生物传感器，满足严格的权威规定。 传感器不仅灵敏度高，而且与经典的ELISA方法相比也很快，LOD为0.04 ng mL-1，整个检测过程持续时间少于30 min。 本发明的另一个显着的优点是传感器的通用性，类似的方法被用于制备用于其它氨基糖苷类抗生素的通用传感器，用相关抗体替代。
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公开(公告)号：US07620214B2
公开(公告)日：2009-11-17
申请号：US10736686
申请日：2003-12-17
Applicant: Xinwu Chen , Xin Ji , Libing Wang
Inventor： Xinwu Chen , Xin Ji , Libing Wang
CPC classification number: G06K9/00597
Abstract: The invention relates to a human eye detection method, apparatus, system and storage medium. According to the invention, candidate eye areas are detected from a given image by: reading in the image; analyzing the image and getting a list of candidate eye areas; selecting one unverified candidate eye area from said list; determining a neighborhood region of the selected candidate eye area; calculating the neighborhood region's size, which is recorded as S; processing the region, obtaining dark areas; counting the number of dark areas, which number is recorded as N; comparing the ratio N/S to a predetermined first threshold, if the ratio N/S is smaller than said first threshold, the candidate eye area is determined as a false eye area and deleted from the list; else, the candidate eye area is determined as a real eye area and remains in the list; repeating foresaid selecting step to comparing step until there is no unverified candidate eye area in the list; and outputting the list for purpose of subsequent processing of the image. The invention may be applied to human body detection.
Abstract translation: 本发明涉及人眼检测方法，装置，系统和存储介质。 根据本发明，通过以下方式从给定图像中检测候选眼睛区域：在图像中读取; 分析图像并获取候选眼睛区域的列表; 从所述列表中选择一个未验证的候选眼睛区域; 确定所选择的候选眼睛区域的邻域区域; 计算邻域区域的大小，记录为S; 加工区域，获得黑色区域; 计数黑暗区域的数量，其数量记录为N; 将比率N / S与预定的第一阈值进行比较，如果比率N / S小于所述第一阈值，则将候选眼睛区域确定为假眼区域并从列表中删除; 另外，候选眼睛区域被确定为真实的眼睛区域并保留在列表中; 重复前述选择步骤来比较步骤，直到列表中没有未验证的候选眼睛区域; 并输出该列表以便后续处理图像。 本发明可以应用于人体检测。
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4.发明授权Versatile electrochemical paper-immunosensor and method for detection of aminoglycoside antibiotics by using the sensor 有权多功能电化学纸免疫传感器和使用传感器检测氨基糖苷类抗生素的方法公开(公告)号：US08926808B2
公开(公告)日：2015-01-06
申请号：US13304496
申请日：2011-11-25
Applicant: Chuanlai Xu , Libing Wang , Xiaoling Wu , Hua Kuang , Wei Chen , Wei Ma
Inventor： Chuanlai Xu , Libing Wang , Xiaoling Wu , Hua Kuang , Wei Chen , Wei Ma
IPC: G01N33/487 , B82Y30/00 , G01N33/53 , G01N33/543 , G01N33/551
CPC classification number: B82Y30/00 , G01N33/5308 , G01N33/5438 , G01N33/551
Abstract: An electrochemical paper-immunosensor and method for detecting aminoglycoside antibiotics is developed in the present invention. Single-walled carbon nanotubes are coated on the common filtration paper by dip-dry cycles. With antibody against neomycin adding to the coating solution, a high sensitive biosensor for specific detection of neomycin is prepared, satisfying to the rigid authority regulations. The sensor is not only sensitive but also rapid, comparing with the classic ELISA method, with LOD of 0.04 ng mL−1 and the whole detection process lasting less than 30 min. Another notable advantage of this invention is the versatility of the sensor, similar method is engaged to prepare the versatile sensor for other aminoglycoside antibiotics, replacement with relevant antibodies.
Abstract translation: 在本发明中开发了一种用于检测氨基糖苷类抗生素的电化学纸免疫传感器和方法。 单壁碳纳米管通过浸渍 - 干燥循环涂布在普通的滤纸上。 用新霉素抗体加入涂层溶液中，制备了一种用于特异性检测新霉素的高灵敏度生物传感器，满足严格的权威规定。 传感器不仅灵敏度高，而且与经典的ELISA方法相比也很快，LOD为0.04 ng mL-1，整个检测过程持续时间少于30 min。 本发明的另一个显着的优点是传感器的通用性，类似的方法被用于制备用于其它氨基糖苷类抗生素的通用传感器，用相关抗体替代。
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Patent Agency Ranking
公开(公告)号：US08822184B2
公开(公告)日：2014-09-02
申请号：US13462612
申请日：2012-05-02
Applicant: Libing Wang , Chuanlai Xu , Liguang Xu , Xiaoling Wu
Inventor： Libing Wang , Chuanlai Xu , Liguang Xu , Xiaoling Wu
CPC classification number: C12P19/34 , B82Y20/00 , C07H21/04 , Y10S977/773 , Y10S977/885
Abstract: Multiple properties of plasmonic assemblies are determined by their geometrical organization. This patent focuses on the formation of Janus structure of the asymmetric assembly structure of the gold nanorods and gold nanoparticles. Chiral structure of gold nanorods and gold nanoparticles can be obtained through the characterization of optical spectra of the Janus structure. And it opens the door for the explanation of the mechanism of the chirality, plays a strong guiding role in the negative refractive material above and has good application prospects.
Abstract translation: 等离子体组件的多个性质由其几何组织决定。 该专利着重于金纳米棒和金纳米粒子的非对称组装结构的Janus结构的形成。 金纳米棒和金纳米颗粒的手性结构可以通过对Janus结构的光谱进行表征而获得。 它为手性机制的解释打开了大门，在上述负折射材料中起着很强的引导作用，具有良好的应用前景。
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6.发明授权公开(公告)号：US08513030B2
公开(公告)日：2013-08-20
申请号：US13464759
申请日：2012-05-04
Applicant: Libing Wang , Chuanlai Xu , Zhou Xu
Inventor： Libing Wang , Chuanlai Xu , Zhou Xu
IPC: G01N33/553
CPC classification number: G01N33/54346 , B82Y30/00 , B82Y40/00
Abstract: A universal chirality sensor based on immuno-recognition-driven nanoparticle assembly has been fabricated. The design of smart 10 nm AuNP-antigen and 20 nmAuNP-antibody described for the detection of aflatoxin B1. 10 nm AuNP-antigen and 20 nmAuNP-antibody assemble to symmetric plasmonic nanoparticle dimers, which induced CD signal. The addition of aflatoxin B1 to the chirality sensor resulted in transverse CD signal compared to a blank control as shown by CD measurements. This process also allowed the rapid and facile determination of concentrations of aflatoxin B1 in drinking water (tap water). Good linearity for all calibration curves was obtained, and the limit of detection (LOD) for aflatoxin B1 was 0.02 ng/mL in tap water.
Abstract translation: 已经制造了基于免疫识别驱动的纳米颗粒组装的通用手性传感器。 智能10 nm AuNP抗原和20 nmAuNP抗体的设计，用于检测黄曲霉毒素B1。 10 nm AuNP抗原和20 nmAuNP抗体组装到对称等离子体纳米颗粒二聚体，诱导CD信号。 将黄曲霉毒素B1添加到手性传感器中导致横向CD信号与空白对照相比较，如CD测量所示。 这一过程还可以快速，轻松地确定饮用水（自来水）中黄曲霉毒素B1的浓度。 获得了所有校准曲线的线性良好，自来水中黄曲霉毒素B1的检出限（LOD）为0.02 ng / mL。
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7.发明申请CHIRALITY SENSOR AND METHOD FOR DETECTION OF AFLATOXIN BY USING THE SENSOR 有权CHIRALITY传感器和使用传感器检测AFLATOXIN的方法公开(公告)号：US20130071947A1
公开(公告)日：2013-03-21
申请号：US13464759
申请日：2012-05-04
Applicant: Libing WANG , Chuanlai Xu , Zhou Xu
Inventor： Libing WANG , Chuanlai Xu , Zhou Xu
CPC classification number: G01N33/54346 , B82Y30/00 , B82Y40/00
Abstract: A universal chirality sensor based on immuno-recognition-driven nanoparticle assembly has been fabricated. The design of smart 10 nm AuNP-antigen and 20 nmAuNP-antibody described for the detection of aflatoxin B1. 10 nm AuNP-antigen and 20 nmAuNP-antibody assemble to symmetric plasmonic nanoparticle dimers, which induced CD signal. The addition of aflatoxin B1 to the chirality sensor resulted in transverse CD signal compared to a blank control as shown by CD measurements. This process also allowed the rapid and facile determination of concentrations of aflatoxin B1 in drinking water (tap water). Good linearity for all calibration curves was obtained, and the limit of detection (LOD) for aflatoxin B1 was 0.02 ng/mL in tap water.
Abstract translation: 已经制造了基于免疫识别驱动的纳米颗粒组装的通用手性传感器。 智能10 nm AuNP抗原和20 nmAuNP抗体的设计，用于检测黄曲霉毒素B1。 10 nm AuNP抗原和20 nmAuNP抗体组装到对称等离子体纳米颗粒二聚体，诱导CD信号。 将黄曲霉毒素B1添加到手性传感器中导致横向CD信号与空白对照相比较，如CD测量所示。 这一过程还可以快速，轻松地确定饮用水（自来水）中黄曲霉毒素B1的浓度。 获得了所有校准曲线的线性良好，自来水中黄曲霉毒素B1的检出限（LOD）为0.02 ng / mL。
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公开(公告)号：US07415137B2
公开(公告)日：2008-08-19
申请号：US10716671
申请日：2003-11-20
Applicant: Xinwu Chen , Xin Ji , Libing Wang , Yoshihiro Ishida
Inventor： Xinwu Chen , Xin Ji , Libing Wang , Yoshihiro Ishida
CPC classification number: G06K9/00228
Abstract: A method of processing an image includes steps of identifying one candidate for a human face region within an image; calculating a probability that the candidate for human face region represents a human face; and saving the probability as attached information to the image. The method of processing an image can also include steps of identifying one candidate for human face region within an image; calculating a probability that the candidate for human face region represents a human face; judging whether or not the candidate for human face region represents a human face by comparing the probability with a threshold; and saving a result of the step of judging as attached information to the image. According to these methods, results of identifying candidates for human face regions will be saved to the image, and further processes to be conducted on the image can be facilitated.
Abstract translation: 处理图像的方法包括识别图像内的人脸区域的一个候选者的步骤; 计算人脸区域候选人代表人脸的概率; 并将概率作为附加信息保存到图像。 处理图像的方法还可以包括识别图像内的人脸区域的一个候选者的步骤; 计算人脸区域候选人代表人脸的概率; 通过将概率与阈值进行比较来判断人脸区域的候选人是否代表人脸; 并且将作为附加信息判断的步骤的结果保存到图像。 根据这些方法，将识别人脸区域的候选者的结果将被保存到图像中，并且可以促进对图像进行的进一步处理。
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公开(公告)号：US07403636B2
公开(公告)日：2008-07-22
申请号：US10704591
申请日：2003-11-12
Applicant: Xinwu Chen , Xin Ji , Libing Wang
Inventor： Xinwu Chen , Xin Ji , Libing Wang
CPC classification number: G06K9/00248
Abstract: The present invention provides a method of processing an image, which includes the steps of identifying one candidate for human face region within the image, selecting a mouth neighborhood within the candidate for human face region, processing the mouth neighborhood, and classifying the candidate for human face region based on results of the processing step. According to the method of the present invention, human faces are detected just based on pixels included in the mouth neighborhood, but not all the pixels of the entire face.
Abstract translation: 本发明提供了一种处理图像的方法，包括以下步骤：识别图像内的人脸区域的一个候选者，在人脸区域的候选者内选择嘴部邻域，处理嘴部邻域，并对人类的候选人进行分类 基于处理步骤的结果的脸部区域。 根据本发明的方法，仅基于包括在嘴部邻域中的像素而不是整个脸部的全部像素来检测人脸。
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