公开(公告)号：US20140066571A1

公开(公告)日：2014-03-06

申请号：US14004362

申请日：2012-03-12

Applicant: Ryoichi Takasawa ,  Takuya Oka ,  Yukinori Kohama ,  Miharu Nakagawa ,  Keiji Iwamoto ,  Kenji Hirotsu ,  Yoshiyuki Watanabe

Inventor： Ryoichi Takasawa ,  Takuya Oka ,  Yukinori Kohama ,  Miharu Nakagawa ,  Keiji Iwamoto ,  Kenji Hirotsu ,  Yoshiyuki Watanabe

IPC: C08G73/14 ,  C08G69/00

CPC classification number: C08G73/1085 ,  B05D1/30 ,  B05D3/0254 ,  B05D3/0413 ,  B29C39/02 ,  B29C39/22 ,  B29K2079/08 ,  B29K2995/0012 ,  B29K2995/0016 ,  B29K2995/0026 ,  B29K2995/0037 ,  B29K2995/0082 ,  B29L2031/34 ,  C08G69/00 ,  C08G73/0644 ,  C08G73/1078 ,  C08G73/14 ,  C08J5/18 ,  C08J2379/08 ,  C09D179/08 ,  H01L31/03926 ,  H01M14/005 ,  Y02E10/50

Abstract: A polyimide precursor comprising a repeating unit represented by the following chemical formula (1): in which A is a tetravalent group having at least one aliphatic six-membered ring and no aromatic ring in the chemical structure, and B is a divalent group having at least one amide bond and an aromatic ring in the chemical structure; or A is an aliphatic tetravalent group and B is a divalent group having at least one chemical structure represented by the following chemical formula (2) in the chemical structure: and X1 and X2 are each independently hydrogen, a C1-6 alkyl group or a C3-9 alkylsilyl group.

Abstract translation: 包含由以下化学式（1）表示的重复单元的聚酰亚胺前体：其中A是在化学结构中具有至少一个脂族六元环且不具有芳环的四价基团，B是具有 化学结构中最少一个酰胺键和芳环; 或A是脂族四价基团，B是在化学结构中具有由以下化学式（2）表示的至少一种化学结构的二价基团：X 1和X 2各自独立地为氢，C 1-6烷基或 C3-9烷基甲硅烷基。

公开(公告)号：US08367824B2

公开(公告)日：2013-02-05

申请号：US10502734

申请日：2003-01-28

Applicant: Shigeyoshi Nishino ,  Kenji Hirotsu ,  Hidetaka Shima ,  Takashi Harada ,  Hiroyuki Oda

Inventor： Shigeyoshi Nishino ,  Kenji Hirotsu ,  Hidetaka Shima ,  Takashi Harada ,  Hiroyuki Oda

IPC: C07D239/72

CPC classification number: C07D239/88 ,  C07C67/31 ,  C07C69/92 ,  C07C201/08 ,  C07C205/59 ,  C07C205/60 ,  C07C227/04 ,  C07C229/56 ,  C07C229/64 ,  C07D239/90

Abstract: A process for producing a quinazolin-4-one compound having the formula: [wherein R1, R2, R3 and R4 each represents a group not participating in the below-mentioned reaction, and R1, R2, R3 and R4 can be combined together to form a ring] which comprises reacting an anthranilic acid derivative having the formula: [wherein R5 is a hydrogen atom or a hydrocarbyl group] with a formic acid derivative in the presence of an ammonium carboxylate.

Abstract translation: 制备具有下式的喹唑啉-4-酮化合物的方法：其中R 1，R 2，R 3和R 4各自表示不参与下述反应的基团，R 1，R 2，R 3和R 4可以组合在一起至 形成环]，其包括在羧酸铵存在下使具有式[其​​中R5是氢原子或烃基]的邻氨基苯甲酸衍生物与甲酸衍生物反应。

公开(公告)号：US08247583B2

公开(公告)日：2012-08-21

申请号：US12303603

申请日：2007-06-05

Applicant: Kenji Hirotsu ,  Tadashi Murakami

Inventor： Kenji Hirotsu ,  Tadashi Murakami

IPC: C07D305/06

CPC classification number: C07D305/06

Abstract: Disclosed is a 3-ethyloxethane compound having a hydroxyl group which is represented by the following general formula (1). (1) (In the formula, A represents an alkylene group having 3-5 carbon atoms which may have an ether bond or an alkylene group having 3-5 carbon atoms which may be substituted by a hydroxyl group.) The 3-ethyloxethane compound having a hydroxyl group can be produced by reacting a 3-ethyloxethane compound represented by the general formula (2) below, a diol compound represented by the general formula (3) below and a base. (2) (In the formula, X represents a leaving group.) (3) (In the formula, A is as defined above.)

Abstract translation: 公开了具有由以下通式（1）表示的羟基的3-乙氧基乙烷化合物。 （1）（式中，A表示可具有醚键的3-5个碳原子的亚烷基或可被羟基取代的具有3-5个碳原子的亚烷基。）3-乙氧基乙烷化合物 具有羟基的化合物可以通过下述通式（2）表示的3-乙基氧化乙烷化合物，下述通式（3）表示的二醇化合物和碱反应来制造。 （2）（式中，X表示离去基团）（3）（式中，A如上定义）

公开(公告)号：US20090253909A1

公开(公告)日：2009-10-08

申请号：US12484632

申请日：2009-06-15

Applicant: Shigeyoshi NISHINO ,  Kenji HIROTSU ,  Hidetaka SHIMA ,  Hiroyuki ODA ,  Shinobu SUZUKI

Inventor： Shigeyoshi NISHINO ,  Kenji HIROTSU ,  Hidetaka SHIMA ,  Hiroyuki ODA ,  Shinobu SUZUKI

IPC: C07D239/88

CPC classification number: C07D239/88 ,  C07C67/31 ,  C07C69/92

Abstract: 6,7-Bis(2-methoxyethoxy)quinazolin-4-one of formula (5) useful in synthesis of an anti-cancer drug can be prepared by a reaction of ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate of formula (4) with an orthoformic acid in the presence of an ammonium acetate:

Abstract translation: 可用于合成抗癌药物的式（5）的6,7-双（2-甲氧基乙氧基）喹唑啉-4-酮可以通过2-氨基-4,5-双（2-甲氧基乙氧基 ）苯甲酸酯与原甲酸在乙酸铵存在下反应：

公开(公告)号：US20080177069A1

公开(公告)日：2008-07-24

申请号：US12051605

申请日：2008-03-19

Applicant: Shigeyoshi NISHINO ,  Kenji HIROTSU ,  Hidetaka SHIMA ,  Takashi HARADA ,  Hiroyuki ODA

Inventor： Shigeyoshi NISHINO ,  Kenji HIROTSU ,  Hidetaka SHIMA ,  Takashi HARADA ,  Hiroyuki ODA

IPC: C07D239/94

CPC classification number: C07D239/88 ,  C07D239/94

Abstract: A 4-aminoquinazoline derivative can be obtained by the steps of reacting quinazolin-4-one or its derivative with a chlorinating agent in a first organic solvent in the presence of an organic base, and subsequently reacting the reaction product with an amine compound represented by the formula R5—NH—R6 (each of R5 and R6 represents hydrogen or an optionally substituted hydrocarbyl group) in the presence of a second organic solvent.

Abstract translation: 4-氨基喹唑啉衍生物可以通过以下步骤获得：将喹唑啉-4-酮或其衍生物与氯化剂在有机碱存在下在第一有机溶剂中反应，然后使反应产物与由 式R 5 -NH-R 6（R 5和R 6各自表示氢或任选地 取代的烃基）在第二有机溶剂的存在下进行。

公开(公告)号：US07304169B2

公开(公告)日：2007-12-04

申请号：US10516756

申请日：2003-06-10

Applicant: Shigeyoshi Nishino ,  Kenji Hirotsu ,  Hidetaka Shima ,  Shinobu Suzuki

Inventor： Shigeyoshi Nishino ,  Kenji Hirotsu ,  Hidetaka Shima ,  Shinobu Suzuki

IPC: C07D309/12

CPC classification number: C07D309/12

Abstract: The present invention relates to a process for preparing tetrahydropyran-4-ol which comprises the steps of (A) a cyclization step of preparing tetrahydropyranyl-4-formate represented by the formula (1): by reacting 3-buten-1-ol, a formaldehyde compound and formic acid, and (B) then, a solvolysis step of subjecting the tetrahydropyranyl-4-formate to solvolysis to obtain tetrahydropyran-4-ol represented by the formula (2): and an intermediate and a process for preparing the same.

Abstract translation: 本发明涉及一种制备四氢吡喃-4-醇的方法，其包括以下步骤：（A）制备由式（1）表示的四氢吡喃基-4-甲酸盐的环化步骤：

公开(公告)号：US20070043107A1

公开(公告)日：2007-02-22

申请号：US10583473

申请日：2004-12-17

Applicant: Shigeyoshi Nishino ,  Kenji Hirotsu ,  Hidetaka Shima ,  Keiji Iwamoto ,  Takashi Harada

Inventor： Shigeyoshi Nishino ,  Kenji Hirotsu ,  Hidetaka Shima ,  Keiji Iwamoto ,  Takashi Harada

IPC: A61K31/35 ,  C07D309/06

CPC classification number: C07D309/06

Abstract: The present invention is to provide a process for preparing an alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound represented by the formula (1): wherein R1 and R2 may be the same or different from each other, and represent a group which does not participate in the reaction, and R1 and R2 may be bonded to form a ring, and the ring may contain a hetero atom(s), and R3 represents a hydrocarbon group, which comprises reacting 4-acyltetrahydropyran represented by the formula (2): wherein R1 and R2 have the same meanings as defined above, and a carbonic acid diester represented by the formula (3): wherein R3 has the same meanings as defined above, and two R3s may be bonded to each other to form a ring, in the presence of a base, and a process for preparing 4-acyltetrahydropyran.

Abstract translation: 本发明提供一种制备由式（1）表示的3-（4-四氢吡喃基）-3-氧代丙酸烷基酯化合物的方法：其中R 1和R 2， SUP>可以相同也可以不同，表示不参与反应的基团，R 1和R 2可以相互键合形成 环可以含有杂原子，R 3表示烃基，其包括使由式（2）表示的4-酰基四氢吡喃：其中R 1， / O 2和R 2具有与上述相同的含义，和由式（3）表示的碳酸二酯：其中R 3具有与所定义的相同的含义 并且两个R 3可以在碱的存在下彼此键合形成环，以及制备4-酰基四氢吡喃的方法。

公开(公告)号：US06689895B2

公开(公告)日：2004-02-10

申请号：US10363415

申请日：2003-03-03

Applicant: Katsumasa Harada ,  Yasuhisa Fukuda ,  Yoshinori Yamanaka ,  Tadashi Murakami ,  Kenji Hirotsu

Inventor： Katsumasa Harada ,  Yasuhisa Fukuda ,  Yoshinori Yamanaka ,  Tadashi Murakami ,  Kenji Hirotsu

IPC: C07C25509

CPC classification number: C07C255/09

Abstract: The present invention relates to a novel compound 4,8-dodecadienedinitrile represented by the following formula (1): wherein means a cis or trans bond, and a process for preparing 4,8-dodecadienedinitrile which comprises reacting a 2-alkoxy-5,9-cyclododecadienone oxime or a 2-halogeno-5,9-cyclododecadienone oxime with formic acid and hydroxylamine.

Abstract translation: 本发明涉及由下式（1）表示的新化合物4,8-十二烷二腈：其中为顺式或反式键，以及制备4,8-十二二氰基腈的方法，其包括使2-烷氧基-5,9 - 环十二碳二烯酮肟或2-卤代-5,9-环十二碳二烯肟与甲酸和羟胺。

公开(公告)号：US08901254B2

公开(公告)日：2014-12-02

申请号：US13638550

申请日：2011-03-28

Applicant: Youichi Yoshida ,  Yasuhito Yamamoto ,  Kenji Hirotsu

Inventor： Youichi Yoshida ,  Yasuhito Yamamoto ,  Kenji Hirotsu

IPC: C08F283/00 ,  C08G64/04 ,  C12P7/62 ,  C08G64/02 ,  C08G64/42 ,  C08F283/02

CPC classification number: C08G64/42 ,  C08G64/0291 ,  C08G64/045 ,  C12P7/62

Abstract: This is to provide a process for preparing a polycarbonate diol diacrylate from a polycarbonate diol and a vinyl acrylate compound without using a protonic acid or a metal component.This is a process for preparing a polycarbonate diol diacrylate which comprises reacting a polycarbonate diol represented by the formula (I) and a vinyl acrylate compound represented by the formula (II) in the presence of a hydrolase, and a polycarbonate diol diacrylate represented by the formula (III) having a terminal acrylated ratio of 97% or more.

Abstract translation: 这是提供从聚碳酸酯二醇和丙烯酸乙酯化合物制备聚碳酸酯二醇二丙烯酸酯而不使用质子酸或金属成分的方法。 这是制备聚碳酸酯二醇二丙烯酸酯的方法，该方法包括使式（I）表示的聚碳酸酯二醇和由式（II）表示的丙烯酸乙酯化合物在水解酶的存在下反应，和由 末端丙烯酸酯化率为97％以上的式（III）。

公开(公告)号：US08293448B2

公开(公告)日：2012-10-23

申请号：US12304962

申请日：2007-06-15

Applicant: Takashi Ito ,  Tsuneo Hagiwara ,  Kenji Hirotsu ,  Tadashi Murakami

Inventor： Takashi Ito ,  Tsuneo Hagiwara ,  Kenji Hirotsu ,  Tadashi Murakami

IPC: G03C9/00 ,  G03C5/00 ,  G03F7/00

CPC classification number: C08F2/50 ,  B33Y70/00 ,  C08G59/18 ,  C08L63/00 ,  G03F7/0037 ,  G03F7/038

Abstract: Provided is a resin composition for stereolithography that absorbs little water and moisture over time in uncured state, maintains a low moisture absorption rate even under high humidity, and has high curing sensitivity, from which a stereolithography product excellent in the properties, such as dimensional accuracy, mechanical properties, and dimensional stability can be smoothly produced for reduced light irradiation time. The resin composition for stereolithography comprising an oxetane compound expressed by the general formula (I) below: wherein R1 denotes an alkyl group having 1 to 5 carbon atoms, and R2 denotes an alkylene group having 2 to 10 carbon atoms that may contain an ether bond, in the proportion of from 3 to 60 mass % based on the total mass of the resin composition for stereolithography.

Abstract translation: 提供一种用于立体光刻的树脂组合物，其在未固化状态下随时间吸收几乎没有水分和水分，即使在高湿度下也保持低吸湿率，并且具有高固化灵敏度，由此可以获得诸如尺寸精度的性能优异的立体光刻产品 ，可以平滑地产生机械性能和尺寸稳定性，以减少光照射时间。 用于立体光刻的树脂组合物，其包含由以下通式（I）表示的氧杂环丁烷化合物：其中R 1表示具有1至5个碳原子的烷基，R 2表示可含有醚键的具有2至10个碳原子的亚烷基 ，以用于立体光刻的树脂组合物的总质量为3〜60质量％的比例。