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公开(公告)号：US5270182A
公开(公告)日：1993-12-14
申请号：US879398
申请日：1992-05-07
Applicant: Christopher M. M. Franco , Dilip J. Upadhyay , Louis E. L. Coutinho , Bimal N. Ganguli , Jurgen Blumbach , Hans-Wolfram Fehlhaber , Herbert Kogler
Inventor： Christopher M. M. Franco , Dilip J. Upadhyay , Louis E. L. Coutinho , Bimal N. Ganguli , Jurgen Blumbach , Hans-Wolfram Fehlhaber , Herbert Kogler
IPC: A61K31/65 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/04 , C07D493/04 , C07H17/06 , C07H17/07 , C12N1/20 , C12P17/02 , C12P17/06 , C12P19/60 , C12R1/465 , C07D311/78 , C07H15/26
CPC classification number: C12R1/465 , C07H17/07 , C12P19/605 , Y10S435/886
Abstract: The novel compounds of formulas I and II ##STR1## have an antibiotic activity.
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2.发明授权9-substituted compounds of 3.alpha., 11.alpha.-epoxy-3,4,5,5a.alpha.,6,7,8,8a,9,11,11a-undecahydro-3.beta.,6.al pha.,9-trimethylfurano[3,4-j][1,2]benzodioxepin, processes for their preparation and their use as antiprotozoal and antiviral agents 失效3（ALPHA），11（ALPHA）-EPOXY-3,4,5,5A（ALPHA），6,7,8,8A，9,11,11A-UNDECAHYDRO-3（BETA）的6 - 取代的化合物，6 （ALPHA），9-三甲基呋喃（3,4-J）（1,2）苯并二恶英，其制备方法及其作为抗真菌剂和抗病毒剂的用途
公开(公告)号：US5246930A
公开(公告)日：1993-09-21
申请号：US694203
申请日：1991-05-03
Applicant: Bindumadhavan Venugopalan , Chintamani P. Bapat , Pravin J. Karnik , Bansi Lal , Dipak K. Chatterjee , Subramani N. Iyer , Jurgen Blumbach
Inventor： Bindumadhavan Venugopalan , Chintamani P. Bapat , Pravin J. Karnik , Bansi Lal , Dipak K. Chatterjee , Subramani N. Iyer , Jurgen Blumbach
IPC: A61K31/34 , A61P31/12 , A61P33/02 , C07D493/18 , C07D493/20
CPC classification number: C07D493/20
Abstract: Compounds of formula I ##STR1## in which the substituted R has the given meaning, have an antimalarial and a antiviral activity.
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公开(公告)号：US5114967A
公开(公告)日：1992-05-19
申请号：US639343
申请日：1991-01-10
Applicant: Christopher M. M. Franco , Erra K. S. Vijayakumar , Sugata Chatterjee , Bimal N. Ganguli , Jurgen Blumbach , Herbert Kogler , Hans-Wolfram Fehlhaber
Inventor： Christopher M. M. Franco , Erra K. S. Vijayakumar , Sugata Chatterjee , Bimal N. Ganguli , Jurgen Blumbach , Herbert Kogler , Hans-Wolfram Fehlhaber
IPC: A61K31/335 , A61K31/336 , A61P31/04 , A61P33/10 , A61P35/00 , C07D303/32 , C07D303/46 , C12P17/02 , C12R1/465
CPC classification number: C12R1/04 , C07D303/46 , C12P17/02
Abstract: Alisamycin, a compound of the formula I ##STR1## has an antibiotic, antitumor and antiparasitic action.
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公开(公告)号：US4454129A
公开(公告)日：1984-06-12
申请号：US373790
申请日：1982-04-30
Applicant: Burkhard Mencke , Eberhard Ehlers , Jurgen Blumbach , Walter Durckheimer , Karl Seeger
Inventor： Burkhard Mencke , Eberhard Ehlers , Jurgen Blumbach , Walter Durckheimer , Karl Seeger
IPC: A61K31/545 , A61K31/546 , A61P31/04 , C07C235/74 , C07D277/36 , C07D501/34 , C07D501/36 , C07D501/46 , C07D501/56
CPC classification number: C07C235/74 , C07D277/36
Abstract: What are disclosed are cephem compounds of the formula ##STR1## useful for combating bacterial infections, and methods of making and using the same.
Abstract translation: 所公开的是用于对抗细菌感染的具有式（IMAGE）+ TR＆lt; IMAGE＆gt;的头孢烯化合物及其制备和使用方法。
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公开(公告)号：US6159988A
公开(公告)日：2000-12-12
申请号：US106110
申请日：1998-06-29
Applicant: Ramachandra Ganapati Naik , Vilas Narayan Mumbaikar , Ravishankar Vasumathy , Aftab Dawoodbhai Lakdawala , Mandakini Bipin Alreja , Bansi Lal , Jurgen Blumbach , Klaus Ulrich Weithmann , Robert Ryder Bartlett , Kalpana Sanjay Joshi , Swati Bal-Tembe , Sadagopan Raghavan
Inventor： Ramachandra Ganapati Naik , Vilas Narayan Mumbaikar , Ravishankar Vasumathy , Aftab Dawoodbhai Lakdawala , Mandakini Bipin Alreja , Bansi Lal , Jurgen Blumbach , Klaus Ulrich Weithmann , Robert Ryder Bartlett , Kalpana Sanjay Joshi , Swati Bal-Tembe , Sadagopan Raghavan
IPC: C07C45/62 , C07C45/67 , C07C45/74 , C07C49/84 , C07C65/40 , A01N37/00 , A01N37/02 , A01N37/12 , A01N37/34 , A01N37/44 , A01N43/06 , A01N43/08 , A01N43/40 , A01N47/06
CPC classification number: C07C49/84 , C07C45/62 , C07C45/673 , C07C45/74 , C07C65/40
Abstract: Compounds of formula I, ##STR1## and the physiologically tolerable salts thereof, wherein the substituents R.sub.1 -R.sub.4 have the meanings given in the specifications and show an activity against inflammatory conditions.
Abstract translation: 式I化合物及其生理上可耐受的盐，其中取代基R 1 -R 4具有说明书中给出的含义并显示出抗炎症状态的活性。
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Patent Agency Ranking
公开(公告)号：US5589514A
公开(公告)日：1996-12-31
申请号：US444518
申请日：1995-05-19
Applicant: Ramachandra G. Naik , Vilas N. Mumbaikar , Rangarajan Vasumathy , Aftab D. Lakdawala , Mandakini V. Shirole , Bansi Lal , Jurgen Blumbach , Klaus U. Weithmann , Robert R. Bartlett
Inventor： Ramachandra G. Naik , Vilas N. Mumbaikar , Rangarajan Vasumathy , Aftab D. Lakdawala , Mandakini V. Shirole , Bansi Lal , Jurgen Blumbach , Klaus U. Weithmann , Robert R. Bartlett
IPC: A61K31/12 , A61K31/00 , A61K31/121 , A61P11/06 , A61P19/00 , A61P25/04 , A61P29/00 , A61P35/00 , C07C45/67 , C07C45/70 , C07C45/74 , C07C49/796 , C07C49/83 , C07C49/835 , C07C49/84 , C07C65/40 , C07C69/157 , C07C205/45 , C07C229/08 , C07C233/33 , C07C255/56 , C07D207/33 , C07D213/24 , C07D213/38 , C07D307/46 , C07D307/52 , C07D317/54 , C07D333/20 , C07D333/22 , A61K31/165 , C07C59/84
CPC classification number: C07C49/83 , C07C205/45 , C07C229/08 , C07C233/33 , C07C255/56 , C07C45/673 , C07C45/74 , C07C49/835 , C07C49/84 , C07C65/40 , C07D307/46 , C07D317/54 , C07D333/22 , Y10S514/886 , Y10S514/887
Abstract: Compounds of formula I, ##STR1## wherein the substituents R.sub.1 -R.sub.4 and a have the given meanings and show an activity against inflammatory conditions.
Abstract translation: 式I的化合物，其中取代基R 1 -R 4和A具有给定的含义并且表现出对炎症条件的活性。
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7.发明授权Process for the preparation of 6-acyl, 7-acyl, and 6,7-diacyl analogues of forskolin and intermediates thereof 失效毛喉素的6-酰基，7-酰基和6,7-二酰基类似物的制备方法及其中间体
公开(公告)号：US5268471A
公开(公告)日：1993-12-07
申请号：US5163
申请日：1993-01-15
Applicant: Noel J. de Souza , Premanand D. Desai , Shrikant V. Savanur , Jurgen Blumbach
Inventor： Noel J. de Souza , Premanand D. Desai , Shrikant V. Savanur , Jurgen Blumbach
IPC: C07D311/92 , C07D405/12
CPC classification number: C07D311/92
Abstract: Process for the preparation of 6-acyl-, 7-acyl- or 6,7-diacyl analogues of forskolin of the general formula ##STR1##
Abstract translation: 用于制备通式为“IMAGE”的福斯克林的6-酰基，7-酰基或6,7-二酰基类似物的方法，
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公开(公告)号：US4762848A
公开(公告)日：1988-08-09
申请号：US837700
申请日：1986-03-10
Applicant: Karl-Heinz Scheunemann , Walter Durckheimer , Jurgen Blumbach , Michael Limbert , Hans-Ulrich Schorlemmer , Gerhard Dickneite , Hans-Harald Sedlacek
Inventor： Karl-Heinz Scheunemann , Walter Durckheimer , Jurgen Blumbach , Michael Limbert , Hans-Ulrich Schorlemmer , Gerhard Dickneite , Hans-Harald Sedlacek
IPC: A61K31/33 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/425 , A61K31/426 , A61K31/428 , A61K31/433 , A61K31/455 , A61K31/465 , A61K31/53 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/04 , A61P43/00 , C07D211/54 , C07D211/84 , C07D213/80 , C07D231/18 , C07D235/28 , C07D237/18 , C07D239/38 , C07D241/18 , C07D249/12 , C07D253/06 , C07D253/07 , C07D277/20 , C07D277/32 , C07D277/36 , C07D277/46 , C07D277/56 , C07D277/70 , C07D277/74 , C07D285/12 , C07D285/125 , C07D521/00 , A61K31/38 , C07D213/62 , C07D277/34
CPC classification number: C07D213/80 , C07D235/28 , C07D249/12 , C07D253/07 , C07D277/36 , C07D277/46 , C07D277/56 , C07D277/74 , C07D285/125
Abstract: Heterocyclic sulfides of the general formula heterocycle-S-R, a process for their preparation and, in particular, their use for immunostimulation, immunorestoration and cytostatic treatment, and pharmaceutical agents, which contain a sulfide of this type, for these indications.
Abstract translation: 用于这些适应症的通式杂环-S-R的杂环硫化物，其制备方法，特别是其用于免疫刺激，免疫测定和细胞抑制处理的药物和含有这种硫化物的药剂。
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9.发明授权Process for the preparation of 6-(substitutedaminopropionyl)-derivatives of forskolin 失效毛喉素6-（取代氨基丙酰）衍生物的制备方法
公开(公告)号：US5869523A
公开(公告)日：1999-02-09
申请号：US733641
申请日：1991-07-22
Applicant: Noel John de Souza , Adolf D'Sa , Samba Laxminarayan Kattige , Gulab Bajirao Padwal , Jurgen Blumbach
Inventor： Noel John de Souza , Adolf D'Sa , Samba Laxminarayan Kattige , Gulab Bajirao Padwal , Jurgen Blumbach
IPC: A61K31/35 , A61K31/352 , A61P9/00 , A61P9/08 , A61P9/12 , A61P37/04 , C07D311/92 , C07D493/10 , C07D309/20
CPC classification number: C07D311/92
Abstract: Process for the preparation of 6-(substitutedaminopropionyl)-derivatives of forskolinProcess for the manufacture of 6.beta.-(3-substitutedamino) propionyloxy forskolin derivatives of the general formula ##STR1##
Abstract translation: 制备福斯柯林的6-（取代氨基丙酰基）衍生物的方法制备通式为“IMAGE”的6β-（3-取代氨基）丙酰氧基毛喉素衍生物的方法
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10.发明授权Method of blocking nerve conduction by treatment with branched-chain esters of 2-�4-(2-piperidine-ethoxy)-benzoyl!-benzoic acid and pharmaceutically acceptable salts thereof 失效通过用2- [4-（2-哌啶 - 乙氧基） - 苯甲酰基] - 苯甲酸的支链酯处理阻断神经传导的方法及其药学上可接受的盐
公开(公告)号：US5821252A
公开(公告)日：1998-10-13
申请号：US474550
申请日：1995-06-07
Applicant: Swati Bal-Tembe , Jurgen Blumbach , Alihussein Nomanbhai Dohadwalla, deceased , Bansi Lal , Narayan Sudhindra Punekar , Ramanujam Rajgopalan , Richard Helmut Rupp , Martin Bickel
Inventor： Swati Bal-Tembe , Jurgen Blumbach , Alihussein Nomanbhai Dohadwalla, deceased , Bansi Lal , Narayan Sudhindra Punekar , Ramanujam Rajgopalan , Richard Helmut Rupp , Martin Bickel
IPC: A61K31/445 , C07D211/34
CPC classification number: A61K31/445
Abstract: Compounds of the formula III ##STR1## in which R.sub.4 and R.sub.5 are CH.sub.3 amd R.sub.6 is hydrogen, have prolonged spasmolytic and anaesthetic activity.
Abstract translation: 其中R4和R5是CH3的R6的化合物III是氢，具有延长的解痉和麻醉活性。
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