公开(公告)号：US09157884B2

公开(公告)日：2015-10-13

申请号：US13218113

申请日：2011-08-25

申请人： Masayoshi Seike ,  Nobuyasu Hori ,  Seigo Suzuki ,  Shigeki Iwanaga ,  Hiroya Kirimura

发明人： Masayoshi Seike ,  Nobuyasu Hori ,  Seigo Suzuki ,  Shigeki Iwanaga ,  Hiroya Kirimura

IPC分类号： G01N27/26 ,  G01N27/327 ,  G01N27/74

CPC分类号： G01N27/3278 ,  G01N27/745

摘要： In order to provide a method of electrochemically detecting a target substance, a method of electrochemically detecting an analyte, and a detection set which have a theoretical advantage in the measurement sensitivity obtained by a conventional electrochemical detection method using a working electrode with a trapping substance immobilized, can reuse the working electrode, and can detect an analyte regardless of the size thereof, there is provided a method including: attracting the target substance containing a labeling substance in a liquid sample to a working electrode in which a trapping substance for trapping the target substance containing a labeling substance is not present; and electrochemically detecting the target substance containing a labeling substance.

摘要翻译： 为了提供电化学检测目标物质的方法，电化学检测分析物的方法和检测组，其具有通过常规电化学检测方法获得的测量灵敏度的理论上的优势，所述电化学检测方法使用固定有捕获物质的工作电极 可以重复利用工作电极，并且可以检测分析物而不考虑其大小，提供了一种方法，包括：将含有液体样品中的标记物质的目标物质吸引到用于捕获靶的捕获物质的工作电极 不含标签物质的物质不存在; 并电化学检测含有标记物质的目标物质。

公开(公告)号：US5556474A

公开(公告)日：1996-09-17

申请号：US357297

申请日：1994-12-13

申请人： Satoshi Otani ,  Hiroya Kirimura ,  Hajime Kuwahara ,  Takao Tabata ,  Takahiro Nakahigashi ,  Hiroshi Murakami

发明人： Satoshi Otani ,  Hiroya Kirimura ,  Hajime Kuwahara ,  Takao Tabata ,  Takahiro Nakahigashi ,  Hiroshi Murakami

IPC分类号： C23C16/44 ,  C23C16/509 ,  H01J37/32 ,  C23C16/00

CPC分类号： H01J37/32431 ,  C23C16/4401 ,  C23C16/4412 ,  C23C16/5096

摘要： In a plasma processing apparatus, wherein a power application electrode for generating plasma and an electrode opposed thereto are disposed in a process chamber which can be exhausted to attain a predetermined vacuum pressure, an electric power is applied to the power application electrode to generate the plasma from a process gas introduced between the electrodes, and intended plasma processing is effected on a substrate mounted on one of the electrodes in the plasma, the apparatus includes a particle discharge duct which surrounds a periphery and a rear side of the power application electrode and has an opening at a position neighboring to the periphery of the power application electrode, and an exhaust device connected to the duct at a position corresponding to a central portion of the rear side of the power application electrode.

摘要翻译： 在等离子体处理装置中，其中用于产生等离子体的电力施加电极和与其相对的电极设置在能够排出以达到预定真空压力的处理室中，向功率施加电极施加电力以产生等离子体 从引入在电极之间的工艺气体，并且预期的等离子体处理在安装在等离子体中的一个电极上的基板上进行，该装置包括围绕电力施加电极的周边和后侧的颗粒排放管道，并且具有 在与施加电力电极的周围相邻的位置处的开口，以及在与电力施加电极的后侧的中心部分对应的位置连接到管道的排气装置。

公开(公告)号：US09157885B2

公开(公告)日：2015-10-13

申请号：US13244377

申请日：2011-09-24

申请人： Shigeki Iwanaga ,  Hiroya Kirimura

发明人： Shigeki Iwanaga ,  Hiroya Kirimura

IPC分类号： G01N33/487 ,  G01N27/327

CPC分类号： G01N27/3278

摘要： The present invention provides a method for electrochemically detecting a target substance and a method for electrochemically detecting an analyte using a probe holding substrate with a probe for trapping a target substance or an analyte held on the substrate body as well as a test chip and a detection set using the above detection methods.

摘要翻译： 本发明提供了一种用于电化学检测目标物质的方法和使用探针保持基板进行电化学检测分析物的方法，所述探针保持基板具有用于捕获保持在基板主体上的目标物质或分析物的探针以及测试芯片和检测 设置使用上述检测方法。

公开(公告)号：US08920626B2

公开(公告)日：2014-12-30

申请号：US13306710

申请日：2011-11-29

申请人： Seigo Suzuki ,  Masayoshi Seike ,  Shigeki Iwanaga ,  Nobuyasu Hori ,  Hiroya Kirimura

发明人： Seigo Suzuki ,  Masayoshi Seike ,  Shigeki Iwanaga ,  Nobuyasu Hori ,  Hiroya Kirimura

IPC分类号： G01N27/00 ,  G01N33/543

CPC分类号： G01N33/5438

摘要： A sample substance S is captured by a capture substance 10 which is immobilized on a working electrode body 161 to provide a method of electrochemically detecting a sample substance capable of detecting the sample substance with high sensitivity. A complex which includes, on a soluble carrier 21, a sample substance S and a labeled binder 20 that has a modified labeled substance 23 containing a labeled substance 20 bound to modified labeled substance 23 containing a labeled substance 24 and a binder 22 that binds to the sample substance S, formed on the working electrode 161. The soluble carrier 21 is dissolved, and the modified labeled substance 23 is attracted to the working electrode 161.

摘要翻译： 样品物质S被固定在工作电极体161上的捕获物质10捕获，以提供电化学检测能够以高灵敏度检测样品物质的样品物质的方法。 在可溶性载体21上包含样品物质S和标记粘合剂20的复合物，其具有与标记物质20结合的经修饰标记物质23的修饰标记物质23，所述标记物质20与经标记物质24和粘合剂22结合的修饰标记物质23结合， 样品物质S形成在工作电极161上。可溶性载体21溶解，改性标记物23被吸引到工作电极161。

公开(公告)号：US07901978B2

公开(公告)日：2011-03-08

申请号：US11918245

申请日：2006-03-28

申请人： Yukiharu Uraoka ,  Takashi Fuyuki ,  Hiroya Kirimura

发明人： Yukiharu Uraoka ,  Takashi Fuyuki ,  Hiroya Kirimura

IPC分类号： H01L51/40

CPC分类号： H01L29/78672 ,  C30B29/58 ,  H01L21/02532 ,  H01L21/02672 ,  H01L27/1277 ,  H01L29/1029

摘要： The core metal of a protein such as ferritin is used as a nucleus for crystallizing a silicone thin film and then the thus crystallized film is employed in the channel part of a thin-film transistor. By aligning the protein on the surface of amorphous silicone and heating, the crystallinity is controlled. In the case of ferritin, the core diameter of the protein is 7 mm. That is, this protein is highly even in size (i.e., the metal content). Thus, the amount of the protein to be deposited on the amorphous silicone surface can be accurately controlled by controlling the protein core density. Furthermore, the type of the core metal can be altered by chemical reactions and the above method is applicable not only to amorphous silicone but also to amorphous films of various types such as germanium. Thus, the amount of nickel required in crystallization is controlled by using a protein. Moreover, the distribution density of the nickel core is controlled to thereby conduct crystallization at a desired crystal size.

摘要翻译： 蛋白质如铁蛋白的核心金属用作结晶硅氧烷薄膜的核，然后将这样结晶的膜用于薄膜晶体管的沟道部分。 通过将无定形硅氧烷表面上的蛋白质对准并加热，控制结晶度。 在铁蛋白的情况下，蛋白质的核心直径为7mm。 也就是说，该蛋白质的大小（即，金属含量）高度均匀。 因此，可以通过控制蛋白质核密度来精确地控制沉积在非晶硅表面上的蛋白质的量。 此外，核心金属的种类可以通过化学反应而改变，并且上述方法不仅适用于无定形硅氧烷，而且也适用于各种类型的非晶态锗如锗。 因此，通过使用蛋白质来控制结晶所需的镍的量。 此外，控制镍芯的分布密度，从而以期望的晶体尺寸进行结晶。

公开(公告)号：US06192828B1

公开(公告)日：2001-02-27

申请号：US09306990

申请日：1999-05-07

申请人： Eiji Takahashi ,  Hiroya Kirimura

发明人： Eiji Takahashi ,  Hiroya Kirimura

IPC分类号： C23C1600

CPC分类号： H01J37/32091 ,  C23C16/452 ,  C23C16/517 ,  H01J37/32146

摘要： An insulating member is interposed between a film formation chamber container and a plasma chamber container. Both containers are adjacent to and communicated with each other. In the film formation chamber container, a base material holder is provided for holding the base material. Raw material gas is introduced into the plasma chamber container and ionized by high frequency electric discharge, to generate plasma. A high frequency electrode and a high frequency electric power source are provided as a plasma generating unit. There is provided a porous electrode 30, the electric potential of which is the same as that of the plasma chamber container 24, between both chambers 22, 24 to partition both chambers. A pulse electric powder source for impressing bipolar pulse voltage, in which a positive polarity portion and a negative polarity portion are alternately repeated, is provided between the base material holder and both of the plasma chamber container and the porous electrode 30, the electric potential of which is the same as that of the plasma chamber container 24.

摘要翻译： 在成膜室容器和等离子体室容器之间插入绝缘构件。 两个容器相邻并且彼此连通。 在成膜室容器中设置有用于保持基材的基材保持器。 将原料气体引入等离子体室容器中并通过高频放电进行离子化，产生等离子体。 提供高频电极和高频电源作为等离子体发生单元。 在两个腔室22,24之间设置有多孔电极30，其电位与等离子体室容器24的电位相同，以分隔两个腔室。 在基材保持器和等离子体室容器和多孔电极30两者之间设置有用于施加极性部分和负极性部分交替重复的双极性脉冲电压的脉冲电粉源，电位 其与等离子体室容器24的相同。

公开(公告)号：US20120267258A1

公开(公告)日：2012-10-25

申请号：US13452466

申请日：2012-04-20

申请人： Yukiharu URAOKA ,  Bin Zheng ,  Seigo SUZUKI ,  Hiroya KIRIMURA ,  Masayoshi SEIKE ,  Shigeki IWANAGA ,  Nobuyasu HORI

发明人： Yukiharu URAOKA ,  Bin Zheng ,  Seigo SUZUKI ,  Hiroya KIRIMURA ,  Masayoshi SEIKE ,  Shigeki IWANAGA ,  Nobuyasu HORI

IPC分类号： G01N27/26

CPC分类号： G01N33/5438 ,  G01N27/3275

摘要： In order to provide a method for electrochemically detecting an analyte which can detect an analyte with high detection sensitivity, when detecting an analyte S trapped on a working electrode, a label binding substance 90 in which a labeling substance 93 and a first binding substance 92 which traps the analyte S are at least retained on a support 91 composed of polypeptide is brought into contact with the analyte. Alternatively, a complex containing the analyte S and a label binding substance 290 in which a labeling substance 293 is retained on a binding substance 291 which binds to the analyte S via a modulator 292 is formed. Then, the labeling substance present on the working electrode is electrochemically detected.

摘要翻译： 为了提供用于电化学检测能够检测具有高检测灵敏度的分析物的分析物的方法，当检测到捕获在工作电极上的分析物S时，将标记物质93和第一结合物质92 截留分析物S至少保留在由多肽组成的支撑体91上与分析物接触。 或者，形成包含分析物S和标记结合物质290的复合物，其中标记物质293保留在结合物质291上，结合物质291经由调节器292与分析物S结合。 然后，电化学地检测存在于工作电极上的标记物质。

公开(公告)号：US20120161268A1

公开(公告)日：2012-06-28

申请号：US13338986

申请日：2011-12-28

申请人： Shigeki IWANAGA ,  Seigo SUZUKI ,  Masayoshi SEIKE ,  Nobuyasu HORI ,  Hiroya KIRIMURA

发明人： Shigeki IWANAGA ,  Seigo SUZUKI ,  Masayoshi SEIKE ,  Nobuyasu HORI ,  Hiroya KIRIMURA

IPC分类号： H01L31/0224 ,  H01L31/18

CPC分类号： G01N33/5438 ,  G01N27/305 ,  G01N27/3277

摘要： To provide an electrode and working electrode substrate capable of detecting a sample substance, and a manufacturing method capable of producing the electrode by simply operations, the present invention provides, in a photocurrent detection electrode, an adhesive layer containing linker molecules interposed between an electrode body constituted by a semiconductor for receiving electrons released from a test substance by photoexcitation, and a metal layer constituted by a metal.

摘要翻译： 为了提供能够检测样品物质的电极和工作电极基板，以及通过简单的操作能够制造电极的制造方法，本发明在光电流检测电极中提供粘合剂层，该粘合剂层含有介于电极体 由用于接收通过光激发从测试物质释放的电子的半导体和由金属构成的金属层构成。

公开(公告)号：US20120103836A1

公开(公告)日：2012-05-03

申请号：US13277712

申请日：2011-10-20

申请人： Nobuyasu HORI ,  Hiroya KIRIMURA

发明人： Nobuyasu HORI ,  Hiroya KIRIMURA

IPC分类号： G01N27/416 ,  G01N27/327 ,  G01N27/403 ,  G01N27/30

CPC分类号： G01N27/305 ,  G01N33/5438

摘要： A detection device for detecting a test substance which is capable of detecting a test substance and a sample substance with high sensitivity, an electrode substrate, a working electrode, an inspection tip, a method of detecting a test substance, and a method of detecting a sample substance are provided in which a reflective part (reflective layer) is disposed on the working electrode so as to reflect excitation light emitted from a light source and passing through the working electrode toward the working electrode.

摘要翻译： 一种用于检测能够检测测试物质和具有高灵敏度的样品物质的检测物质的检测装置，电极基板，工作电极，检查头，检测物质的方法以及检测方法 提供了在工作电极上设置有反射部（反射层）的反射物质，以便将从光源发出的激发光反射并通过工作电极朝向工作电极。

公开(公告)号：US06391114B1

公开(公告)日：2002-05-21

申请号：US09567077

申请日：2000-05-08

申请人： Hiroya Kirimura

发明人： Hiroya Kirimura

IPC分类号： C23C1600

CPC分类号： H01L21/67167 ,  H01L21/67178 ,  H01L21/67196

摘要： The invention provides a vacuum processing apparatus, in which a substantial installation area is smaller than that of a conventional vacuum processing apparatus having a plurality of processing chambers of the same size and the same number, and easy maintenance can be achieved. More specifically, the invention provides a vacuum processing apparatus including a plurality of processing chambers, which are provided with processing devices for effecting predetermined processing on a target object, can achieve predetermined internal pressures, and can accommodate the target object for effecting predetermined processing under the predetermined pressures. In the vacuum processing apparatus, the plurality of processing chambers are arranged around a central chamber provided for object transfer and being capable of achieving a predetermined internal pressure, and are connected with the central chamber. The plurality of processing chambers are disposed on two or more vertically different levels, and each of the processing chambers and a processing chamber neighboring thereto in the circumferential direction of the central chamber are disposed on different levels, respectively, and overlap only partially each other.

摘要翻译： 本发明提供一种真空处理装置，其中实际安装面积小于具有相同尺寸和相同数量的多个处理室的常规真空处理装置的真空处理装置，并且可以实现容易的维护。 更具体地说，本发明提供了一种真空处理装置，其具有多个处理室，该处理室设置有用于对目标物体进行预定处理的处理装置，能够实现预定的内部压力，并且可以容纳目标物体，以实现在 预定压力。 在真空处理装置中，多个处理室围绕设置于物体转印的中央室设置并能够实现预定的内部压力，并且与中央室连接。 多个处理室设置在两个或更多个垂直不同的水平上，并且在中央室的周向方向上的每个处理室和与其相邻的处理室分别设置在不同的等级上，并且仅部分地彼此重叠。