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    Implantable reservoir and system for delivery of a therapeutic agent
    2.
    发明授权
    Implantable reservoir and system for delivery of a therapeutic agent 有权
    可植入储存器和用于递送治疗剂的系统

    公开(公告)号：US07063691B2

    公开(公告)日：2006-06-20

    申请号：US10801299

    申请日：2004-03-16

    Applicant: Randall S. Nelson ,  Charles L. Truwit

    Inventor： Randall S. Nelson ,  Charles L. Truwit

    IPC: A61M9/22

    CPC classification number: A61M5/14276 ,  A61M5/14236 ,  A61M5/14586 ,  A61M5/148 ,  A61M5/16881 ,  A61M5/1723 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2210/0687 ,  A61M2210/0693

    Abstract: There is disclosed method and apparatus for retaining a reservoir for a therapeutic agent between the scalp and cranium of a subject, including providing a deformable pouch or rigid cylinder for dispensing the therapeutic agent from the reservoir to a location in the body of the subject. In one embodiment, a pump is used to pump the agent from the reservoir to the location in the subject's body. In another example embodiment, there is provided method and apparatus for forming at least one cavity in the cranium of the subject, and placing at least a portion of the pump in the cavity. Power is applied to the pump in a variety of ways.

    Abstract translation: 公开了一种用于在受试者的头皮和头颅之间保留用于治疗剂的贮存器的方法和装置，包括提供可变形袋或刚性圆柱体，用于将治疗剂从储存器分配到受试者体内的位置。 在一个实施例中，泵用于将药剂从储存器泵送到受检者体内的位置。 在另一个示例性实施例中，提供了用于在受试者的头颅中形成至少一个空腔并将泵的至少一部分放置在空腔中的方法和装置。 以各种方式对泵施加功率。

    Method and apparatus for storing guide wires
    3.
    发明授权
    Method and apparatus for storing guide wires 失效
    存储引导线的方法和装置

    公开(公告)号：US06802323B1

    公开(公告)日：2004-10-12

    申请号：US09849791

    申请日：2001-05-04

    Applicant: Charles L. Truwit ,  Randal Nebon

    Inventor： Charles L. Truwit ,  Randal Nebon

    IPC: B08B304

    CPC classification number: A61M25/002

    Abstract: A guide wire holding apparatus includes a tray, one or more raised corrugated areas, a fluid source, a syringe, a valve, a drainage system, and one or more coupling devices. Each of the one or more raised corrugated areas is located on the inner surface of the tray and includes one or more slots. A reservoir is formed by the inner surface of the tray and the tray end caps. A flow of fluid provided by the fluid source or the syringe and controlled by the valve partially fills the reservoir. The height of the fluid in the reservoir is partially controlled by the location of the cap hole. Preferably, the cap hole is located at a height that causes the guide wire, which is shown resting in a slot formed in the one or more raised corrugated areas, to be slightly submerged when fluid is flowing from the fluid source or syringe to the drainage system.

    Abstract translation: 导丝保持装置包括托盘，一个或多个凸起的波纹区域，流体源，注射器，阀，排水系统以及一个或多个联接装置。 一个或多个凸起的波纹区域中的每一个位于托盘的内表面上并且包括一个或多个槽。 储料器由托盘的内表面和托盘端盖形成。 由流体源或注射器提供并由阀控制的流体流部分地填充储存器。 储存器中的流体的高度部分地由盖孔的位置控制。 优选地，盖孔位于使得当流体从流体源或注射器流动到排水口时导致引导线（其被示出放置在形成在一个或多个凸起的波纹区域中的狭槽中）的高度被稍微浸没 系统。

    Briefcase for laptop computer
    4.
    发明授权
    Briefcase for laptop computer 失效
    笔记本电脑公文包

    公开(公告)号：US06257407B1

    公开(公告)日：2001-07-10

    申请号：US09421726

    申请日：1999-10-20

    Applicant: Charles L. Truwit ,  Daryl G. Nelson

    Inventor： Charles L. Truwit ,  Daryl G. Nelson

    IPC: B65D8538

    CPC classification number: A45C5/14 ,  G06F1/1628

    Abstract: A briefcase for a computer includes a first compartment for carrying the computer and peripherals. The first compartment includes a cover which has a hinge mechanism intermediate said cover. The computer briefcase also includes a second compartment attached to the first compartment. The first compartment is accessible from the exterior of the computer briefcase. In other words, the access can be gained to the computer and its peripherals by leaving the computer within the case and opening a cover. The cover is hinged so that the top of the first compartment does not extend above the top of the opened computer. The briefcase also includes a sliding drawer that advances the computer toward the user without having to move the briefcase itself, such that the computer lid may be opened on an airplane. The briefcase also includes a holding mechanism for holding the computer within the first compartment. The computer briefcase can also be part of a luggage system. The bag for holding a computer includes a first portion of an attachment mechanism attached to the exterior of the bag for holding a computer. The first portion of the attachment mechanism can be attached to another briefcase or to a hanging bag.

    Abstract translation: 计算机的公文包包括用于携带计算机和外围设备的第一隔间。 第一隔室包括盖子，该盖子具有位于所述盖子之间的铰链机构。 电脑公文包还包括连接到第一隔间的第二隔间。 第一个隔间可从电脑公文包的外部进入。 换句话说，通过将计算机放在壳体内并打开盖子，可以获得对计算机及其外围设备的访问。 盖子被铰接，使得第一隔间的顶部不延伸在打开的计算机的顶部上方。 公文包还包括滑动抽屉，其使计算机朝向使用者前进，而不必移动公文包本身，使得计算机盖可以在飞机上打开。 公文包还包括用于将计算机保持在第一隔间内的保持机构。 电脑公文包也可以是行李系统的一部分。 用于保持计算机的袋包括附接到袋的外部的用于保持计算机的附接机构的第一部分。 附件机构的第一部分可以附接到另一个公文包或吊袋上。

    Method and apparatus for taking a biopsy
    8.
    发明授权
    Method and apparatus for taking a biopsy 有权
    用于进行活组织检查的方法和装置

    公开(公告)号：US07335165B2

    公开(公告)日：2008-02-26

    申请号：US10894100

    申请日：2004-07-19

    Applicant: Charles L. Truwit ,  Randal Nelson

    Inventor： Charles L. Truwit ,  Randal Nelson

    IPC: A61B17/32

    CPC classification number: A61B10/04 ,  A61B17/320068 ,  A61B17/320783 ,  A61B18/14 ,  A61B2017/00911

    Abstract: There is described method and apparatus for taking a biopsy wherein the apparatus is formed of a biocompatible cylindrical member with an outer wall and a hollow core, the cylindrical member having a longitudinal axis. An opening in the outer wall of the member is provided and a cutting device cuts tissue entering the opening as it travels along the opening. Cut tissue is treated with a coagulating agent or member so that the coagulation occurs concurrently or just after the tissue is cut wherein the coagulation occurs at a trailing edge of the opening as it travels.

    Abstract translation: 描述了用于进行活检的方法和装置，其中装置由具有外壁和中空芯的生物相容性圆柱形构件形成，该圆柱形构件具有纵向轴线。 提供了构件的外壁中的开口，并且切割装置沿着开口行进时切割进入开口的组织。 用凝固剂或构件处理切割的组织，使得凝结同时发生或刚好在组织切割之后发生，其中凝固在其开口的后缘在其行进时发生。

    Intracranial pressure monitoring device and method for use in MR-guided drug delivery
    9.
    发明授权
    Intracranial pressure monitoring device and method for use in MR-guided drug delivery 有权
    用于MR导向药物输送的颅内压力监测装置和方法

    公开(公告)号：US06537232B1

    公开(公告)日：2003-03-25

    申请号：US09541288

    申请日：2000-04-03

    Applicant: John Kucharczyk ,  Charles L. Truwit

    Inventor： John Kucharczyk ,  Charles L. Truwit

    IPC: A61B505

    CPC classification number: A61B5/411 ,  A61B5/031 ,  A61B5/055 ,  A61B5/4839 ,  A61B90/11 ,  A61B2034/2051 ,  A61B2090/365 ,  A61B2090/3958 ,  A61B2562/028 ,  A61M31/005 ,  A61M2025/0057 ,  A61M2025/0073 ,  A61M2210/0693 ,  G01R33/5601 ,  G01R33/563

    Abstract: A device and method for monitoring intracranial pressure during magnetic resonance (MR) image-guided neurosurgical procedures, such as intracranial drug delivery procedures, wherein an MR-compatible microsensor pressure transducer coupled to a pressure sensing diaphragm located a) at the tip, b) on a lateral side, and/or c) in multiple locations of an MR-compatible catheter is inserted into a lateral cerebral ventricle, cerebral cistern, subarachnoid space, subdural or extradural spaces, venous sinuses, or intraparenchymal tissue locations under MR imaging guidance, and is used to record intracranial pressures over hours to days in patients undergoing diagnostic or therapeutic neurologic interventions.

    Abstract translation: 一种用于在磁共振（MR）图像引导神经外科程序（例如颅内药物递送程序）中监测颅内压的装置和方法，其中耦合到位于尖端处的压力感测膜片的MR兼容微传感器压力传感器，b） 在MR成像指导下，在MR相容导管的多个位置和/或c）插入到外侧脑室，脑水箱，蛛网膜下腔，硬膜下或硬膜下腔，静脉窦或实质内组织位置， 并用于在接受诊断或治疗性神经干预的患者中记录数日至数天的颅内压。

    Method of using trajectory guide
    10.
    发明授权
    Method of using trajectory guide 有权
    使用轨迹指南的方法

    公开(公告)号：US06368329B1

    公开(公告)日：2002-04-09

    申请号：US09363510

    申请日：1999-07-29

    Applicant: Charles L. Truwit

    Inventor： Charles L. Truwit

    IPC: A61B1900

    CPC classification number: A61B90/11 ,  A61B34/10 ,  A61B90/36 ,  A61B2017/00243 ,  A61B2017/00398 ,  A61B2017/00539 ,  A61B2017/00911 ,  A61B2090/3954

    Abstract: A surgical method and apparatus for accurately aligning the trajectory of, guiding of, and introducing or withdrawal of an instrument is disclosed. The apparatus includes a base which has a movable member movably attached to the base. The movable member has a passage therein which forms a portion of the trajectory path. A positioning stem further includes a first locator and a second locator. The first and second locators are associated with two different portions of the positioning stem so that they are essentially two points on a line. The first and second locators are also locatable by a scanning or imaging system. The positioning stem is removably attached to said movable member and used to position the movable member. Moving the movable member also moves the passage therein to different trajectories. Once the passage within the movable member more or less is aligned with a target within the body, a locking member locks the movable member into a fixed position. The movable member can be moved to different trajectories using a first hydraulic system. A second hydraulic system can be used to introduce or withdraw an instrument to or from the patient. A mechanical advancement tool can be substituted for the second hydraulic system. The surgical instrument may also be provided with a remote portion for controlling the instrument from a remote location. The instrument can also be computer controlled.

    Abstract translation: 公开了一种用于精确对准仪器的轨迹，引导和引入或撤回的手术方法和装置。 该装置包括具有可移动地附接到基座的可动构件的底座。 可移动部件具有形成轨迹路径的一部分的通道。 定位杆还包括第一定位器和第二定位器。 第一和第二定位器与定位杆的两个不同部分相关联，使得它们基本上是一条直线上的两个点。 第一和第二定位器也可由扫描或成像系统定位。 定位杆可移除地附接到所述可动构件并用于定位可动构件。 移动可移动构件还将其中的通道移动到不同的轨迹。 一旦可动构件中的通道或多或少地与主体内的靶对准，则锁定构件将可动构件锁定在固定位置。 使用第一液压系统可移动构件可移动到不同的轨迹。 可以使用第二液压系统将仪器引入或者从患者身上引出或从患者身上取出。 机械推进工具可以代替第二液压系统。 手术器械还可以设置有用于从远程位置控制仪器的远程部分。 仪器也可以由电脑控制。

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