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11 条记录 (耗时 0.026 秒)

    Transformation of algae for increasing lipid production
    6.
    发明授权
    Transformation of algae for increasing lipid production 有权
    转化藻类以增加脂质生产

    公开(公告)号：US09428779B2

    公开(公告)日：2016-08-30

    申请号：US13576821

    申请日：2011-02-01

    申请人： Christopher Yohn ,  April Brand ,  Michael Mendez ,  Craig A. Behnke

    发明人： Christopher Yohn ,  April Brand ,  Michael Mendez ,  Craig A. Behnke

    IPC分类号： C12P7/64 ,  C07K14/405 ,  C12N15/82

    CPC分类号： C12P7/6463 ,  C07K14/405 ,  C12N15/8247 ,  C12P7/6409

    摘要： The present disclosure provides novel proteins that when over expressed in algae result in an increase or change in fatty acid and/or glycerol lipid production and/or accumulation, without a substantial decrease in the growth rate of the alga or the break down of algal components, such as chlorophyll. The present disclosure also describes methods of using the novel proteins to increase or change the production and/or accumulation of fatty acids and/or glycerol lipids in algae. In addition, these proteins are useful tools in obtaining information about the fatty acid and triacyglyceride (TAG) synthetic pathways in algae.

    摘要翻译： 本公开提供了当藻类中过度表达导致脂肪酸和/或甘油脂质生成和/或积累的增加或改变而不显着降低藻类生长速率或藻类成分分解时的新型蛋白质 ，如叶绿素。 本公开还描述了使用新型蛋白质来增加或改变藻类中脂肪酸和/或甘油脂质的产生和/或积累的方法。 此外，这些蛋白质是获得关于藻类中的脂肪酸和三酰甘油（TAG）合成途径的信息的有用工具。

    Compositions of matter comprising extracted algae oil
    8.
    发明授权
    Compositions of matter comprising extracted algae oil 有权
    包含提取藻油的物质组成

    公开(公告)号：US09200208B2

    公开(公告)日：2015-12-01

    申请号：US14237537

    申请日：2012-08-09

    申请人： Stilianos G. Roussis ,  Richard J. Cranford

    发明人： Stilianos G. Roussis ,  Richard J. Cranford

    IPC分类号： C10G3/00 ,  A23D9/00 ,  A23D9/007 ,  C12P7/64

    CPC分类号： C10G3/00 ,  A23D9/00 ,  A23D9/007 ,  C10G3/42 ,  C10G3/50 ,  C10G2300/1014 ,  C12P7/6409 ,  C12P7/6436 ,  Y02P30/20

    摘要： Crude algae oils produced by practical extraction techniques comprise a wide range of molecular species that can be characterized by advanced analytical techniques. The algae oils comprise a complex mixture of a large number of molecules having varying sizes and therefore varying boiling points, and comprise high nitrogen, oxygen, and fatty acid content, but low sulfur, saturated hydrocarbons, and triglyceride content. Hydrogen/carbon molar ratios are typically greater than 1.6. The wide range of molecular species in the crude algae oils, while unusual compared to conventional refinery feed stocks and vegetable oils, may be upgraded into fuels by conventional refining approaches such as hydrotreating and thermal treatment. Unusual behavior of the algae oils in thermal processing and/or hydrotreatment may provide a high quality product slate, with the flexibility to adjust the product slate due to enhanced cracking behavior exhibited by these algae oils.

    摘要翻译： 通过实际提取技术生产的粗藻油包含可以通过先进分析技术表征的广泛范围的分子种类。 藻油包含大量具有不同大小，因此变化沸点的分子的复杂混合物，并且包含高的氮，氧和脂肪酸含量，但低硫，饱和烃和甘油三酯含量。 氢/碳摩尔比通常大于1.6。 与常规炼油原料和植物油相比，粗藻油中广泛的分子种类可能通过常规精制方法如加氢处理和热处理而升级为燃料。 藻类油在热加工和/或加氢处理中的异常行为可以提供高质量的产品板岩，具有由于这些藻油所表现的增强的裂纹行为而调整产品板岩的灵活性。

    Variant isoprenoid producing enzymes and uses thereof
    10.
    发明授权
    Variant isoprenoid producing enzymes and uses thereof 有权
    变异型异戊二烯生成酶及其用途

    公开(公告)号：US08987433B2

    公开(公告)日：2015-03-24

    申请号：US13260696

    申请日：2010-03-29

    申请人： Michael Mendez ,  Craig A. Behnke ,  Nicole A. Heaps

    发明人： Michael Mendez ,  Craig A. Behnke ,  Nicole A. Heaps

    IPC分类号： C07H21/04 ,  C12P9/00 ,  C12N9/10 ,  C12N9/88

    CPC分类号： C12P9/00 ,  C12N9/1085 ,  C12N9/88

    摘要： This disclosure provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present disclosure provides methods of generating polypeptide variants, for example, variant isoprenoid synthases and/or variant prenyl transferases that have at least one desired property not present in the parent polypeptide. The present disclosure further provides polypeptides and polynucleotides encoding variant polypeptides, as well as vectors and host cells comprising the polynucleotides that encode the variant polypeptides. In other embodiments, the present disclosure provides methods of using the variant polypeptides to generate useful products, such as isoprenoid compounds and/or isoprenoid products.

    摘要翻译： 本公开提供了设计和产生与亲本多肽相比具有改变的性质的多肽变体的方法。 本公开提供了产生多肽变体的方法，例如变体类异戊二烯合酶和/或变体异戊烯基转移酶，其具有在母体多肽中不存在的至少一种所需性质。 本发明还提供编码变体多肽的多肽和多核苷酸，以及包含编码变体多肽的多核苷酸的载体和宿主细胞。 在其它实施方案中，本公开提供使用变体多肽产生有用产物的方法，例如类异戊二烯化合物和/或类异戊二烯产品。