摘要:
Novel triarylphosphinimide derivatives having the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each at the ortho or meta position, represent mono- or disubstituents and are selected from the group consisting of hydrogen, alkyl(C.sub.1 -C.sub.3), alkoxy(C.sub.1 -C.sub.3), trifluoromethyl and halogen; and R.sub.4 is selected from the group consisting of alkyl(C.sub.1 -C.sub.3), alkenyl(C.sub.2 -C.sub.3), alkynyl(C.sub.2 -C.sub.4), cycloalkyl(C.sub.3 -C.sub.5), cycloalkyl(C.sub.3 -C.sub.6)methyl, 4-oxopentyl, 3-tetrahydrofuranyl, 2,3-dihydro-1H-inden-1-yl, 1-alkyl(C.sub.1 -C.sub.3)cyclopentyl, trans-2-alkyl(C.sub.1 -C.sub.3)cyclopentyl, trans-2-alkoxy(C.sub.1 -C.sub.3)cyclopentyl, 1-cyclopropylethyl, 2-methylcyclopropylmethyl, dicyclopropylmethyl, 2-, 3- or 4-pyridinylmethyl, 2-cyclopenten-1-yl, tetrahydro-2H-pyran-4-yl and cis and trans-2-methoxycyclohexyl; with the proviso that when R.sub.4 is alkyl(C.sub.1 -C.sub.3), R.sub.1, R.sub.2 and R.sub.3 may not each be hydrogen ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 are each at the ortho or meta position and are selected from hydrogen and alkyl(C.sub.1 -C.sub.3), and X is an acid addition salt; processes for producing them, compositions containing them, and methods for using them in mammals to effect diuresis; to lower plasma renin levels and to increase cardiac contractility.
摘要:
The novel urethanes, in addition to at least one perfluoroalkyl group, also contain epichlorohydrin groups and dialcohol radicals in the molecule. They are prepared by reacting a fluorine-containing alcohol with epichlorohydrin to give the perfluoroalkyl-epichlorohydrin adduct, reacting this adduct with a di- or triisocyanate to give the perfluoroalkyl-epichlorohydrin-isocyanate adduct and by reacting this adduct with a dialcohol or a monoetherified dialcohol to give the desired urethanes having a perfluoroalkyl group and having epichlorohydrin groups and dialcohol radicals, and by reacting a suitable urethane compound of this type with a perfluoroalkyl-containing di- or triisocyanate to give the desired urethanes having a plurality of perfluoroalkyl groups and having epichlorohydrin groups and dialcoholradicals. The novel urethanes are preferably used for the oleophobic and hydrophobic finishing of textiles.
摘要:
Molecular structures of .beta.-adrenergic antagonists are modified to produce biologically active compounds. The .beta.-antagonists are modified to form molecules of the general structure: ##STR1## wherein R is most generally R"--OCH.sub.2 --, and in some instances is R"--, and R"=an aryl or substituted aryl moiety; R'=--H, --CH.sub.3, or a short chain alkyl moiety; and Y=--OH, or more usually, --OAX or --NHAX, where A=an alkyl, aryl, or aralkyl moiety, and X=a terminal grouping, such as --CH.sub.3, --CF.sub.3 or --(CH.sub.2).sub.n COOH; or AX may be a carrier moiety consisting of a defined peptide or protein.
摘要:
Compounds of the formula ##STR1## are suitable as curing accelerators which can be incorporated into ethylenically unsaturated, cold-curable resins.
摘要:
Novel homocysteine thiolactone bifunctional chelating agents useful for chelating radionuclides to produce a radiodiagnostic agent for use in vivo imaging and a method for producing this chelating agent.
摘要:
This invention relates to a novel acylation process which comprises using as the acylating agent an o-hydroxy-substituted aromatic oxime ester represented by the general formula (I) ##STR1## and mixing said acylating agent with an amine substance represented by the general formula (III) ##STR2## to form a compound represented by the general formula (IV) ##STR3##
摘要:
Multi-ring fluorinated carbamates are disclosed which have excellent anti-soiling properties, durability and resistance to laundering. The compounds are represented by the formula ##STR1## wherein R.sub.f is a fluorinated radical. Compositions containing at least 10% of such compounds are also disclosed, as well as polyester and nylon fibers having such compounds incorporated therein.
摘要:
The invention is directed to a process for the production of an isocyanate which is both stable and liquid at room temperature comprising reacting pure diphenylmethane diisocyanate or crude diphenylmethane diisocyanate with a diol of the formula, ##STR1## wherein R is a C.sub.2 to a C.sub.5 aliphatic radical, at a temperature of from 20.degree. to 110.degree. C., in a ratio such that the resultant product has an isocyanate group content of from 20 to 30%, by weight and to the products produced therefrom.
摘要:
N-benzyloxycarbonyl aspartic acid containing minor contaminating amounts of N-benzyloxycarbonyl aspartyl aspartic acid is purified by subjecting the impure material to alkaline hydrolysis at a pH of from 10 to 12 and at temperatures of from 30.degree. C. to 100.degree. C., preferably 65.degree. C. to 90.degree. C., for a time sufficient to hydrolyze substantially all of the N-benzyloxycarbonyl aspartyl aspartic acid impurity therein. N-benzyloxycarbonyl aspartic acid containing less than 0.2 weight percent of the impurity can be obtained by such treatment.
摘要:
Novel carbaminic acid phenyl esters of the general formula ##STR1## are described, in which R.sub.1 is C.sub.1 -C.sub.2 -alkoxy-C.sub.1 -C.sub.2 -alkyl, di-C.sub.1 -C.sub.2 -alkoxy-C.sub.1 -C.sub.2 -alkyl, cyano-C.sub.1 -C.sub.2 -alkyl, halogen-C.sub.1 -C.sub.2 -alkyl, phenyl-C.sub.1 -C.sub.2 -alkyl, 1,3-dioxolan-2-yl-methyl, 2-methyl-1,3-dioxolan-4-yl-methyl, 2,2-dimethyl-1,3-dioxolan-4-yl-methyl or aminocarbonylmethyl;R.sub.2 is phenyl optionally mono- or disubstituted by one or more substituents selected from the group consisting of halogen, methyl and methoxy; andR.sub.3 is C.sub.1 -C.sub.8 alkyl, C.sub.2 -C.sub.8 alkenyl, cyclopropyl or trichloromethyl, or R.sub.1 is methyl or ethyl, R.sub.2 is .alpha.-cyanobenzyl or 1-cyano-2-phenylethyl and R.sub.3 is ethyl.