公开(公告)号：US20130150745A1

公开(公告)日：2013-06-13

申请号：US13763941

申请日：2013-02-11

Applicant: CARDIAC PACEMAKERS, INC.

Inventor： Viktoria Averina ,  Yi Zhang ,  Yousufali Dalal

IPC: A61B5/08

CPC classification number: A61B5/0803 ,  C07C17/361 ,  C07C19/16

Abstract: Systems and methods provide for assessing the heart failure status of a patient and, more particularly, to generating a trend parameter based on a distribution of the patient's respiration rate. Systems and methods provide for detecting, using an implantable device or a patient-external device, patient respiration and computing a respiration rate based on the detected patient respiration. A distribution of the respiration rate is calculated, and a trend parameter based on the respiration rate distribution is generated. The trend parameter is indicative of a patient's heart failure status. An output signal indicative of the patient's heart failure status may be generated based on the trend parameter.

Abstract translation: 系统和方法提供用于评估患者的心力衰竭状态，更具体地，用于基于患者的呼吸速率的分布来生成趋势参数。 系统和方法提供用于基于检测到的患者呼吸来检测，使用可植入装置或患者外部装置进行患者呼吸并计算呼吸速率。 计算呼吸率的分布，并生成基于呼吸率分布的趋势参数。 趋势参数表示患者的心力衰竭状态。 可以基于趋势参数生成表示患者心力衰竭状态的输出信号。

公开(公告)号：US08357772B2

公开(公告)日：2013-01-22

申请号：US12677579

申请日：2008-08-29

Applicant: Masayosi Horiuti ,  Seiichiro Murata ,  Katsuyuki Sato

Inventor： Masayosi Horiuti ,  Seiichiro Murata ,  Katsuyuki Sato

IPC: C08G61/04 ,  C08G61/00

CPC classification number: C08F114/18 ,  C07C17/278 ,  C07C19/16 ,  C08F14/18 ,  C08F214/18 ,  C08F2/00

Abstract: Provided is a terminally iodized polyfluoroalkane represented by the general formula: CnF2n+1(CHXCFY)s+p(CF2CF2)t+rI  [I] (in the formula, X and Y are each a hydrogen atom or a fluorine atom, wherein when Y is a fluorine atom, X is also a fluorine atom; n is an integer of 1 to 6; s+p is an integer of 1 to 5 and denotes the number of CHXCFY group; and t+r is 0 or an integer of 1 to 6 and denotes the number of tetrafluoroethylene skeleton). The terminally iodized polyfluoroalkane is produced by telomerizing a fluorine-containing olefin CHX═CFY and tetrafluoroethylene, successively, to CnF2n+1I in the presence of a peroxide initiator.

Abstract translation: 提供由以下通式表示的末端碘化多氟烷烃：CnF2n + 1（CHXCFY）s + p（CF2CF2）t + rI [I]（在该式中，X和Y各自为氢原子或氟原子，其中当 Y为氟原子，X为氟原子，n为1〜6的整数，s + p为1〜5的整数，表示CHXCFY基的数，t + r为0或整数 1〜6，表示四氟乙烯骨架的数量）。 末端碘化的多氟烷烃是通过在含有过氧化物引发剂的存在下将含氟烯烃CHX = CFY和四氟乙烯连续地调节至C n F 2n + 1 I来制备的。

公开(公告)号：US08142680B2

公开(公告)日：2012-03-27

申请号：US12519280

申请日：2007-12-17

Applicant: Wissam Rached

Inventor： Wissam Rached

IPC: C09K5/04

CPC classification number: C09K5/045 ,  C07C19/08 ,  C07C19/16 ,  C07C21/18 ,  C07C21/185 ,  C09K2205/106

Abstract: The invention relates to compositions that can be used as refrigerants. More specifically, the invention relates to compositions having a very low contribution to the greenhouse effect, which can be used in the cooling and production of conditioned air. The GWP of the inventive compositions is preferably at most equal to 150.

Abstract translation: 本发明涉及可用作制冷剂的组合物。 更具体地，本发明涉及对温室效应贡献很低的组合物，其可用于冷却和生产调节空气。 本发明组合物的GWP优选至多等于150。

公开(公告)号：US08133407B2

公开(公告)日：2012-03-13

申请号：US12467061

申请日：2009-05-15

Applicant: Gary Zyhowski ,  Rajiv Ratna Singh ,  Raymond H. Thomas ,  Mark W. Spatz ,  Roy P. Robinson ,  George J. Samuels ,  Gregory J. Shafer ,  Michael Van Der Puy ,  David P. Wilson ,  John L. Welch ,  Ronald P. Vogl ,  Samuel F. Yana Motta

Inventor： Gary Zyhowski ,  Rajiv Ratna Singh ,  Raymond H. Thomas ,  Mark W. Spatz ,  Roy P. Robinson ,  George J. Samuels ,  Gregory J. Shafer ,  Michael Van Der Puy ,  David P. Wilson ,  John L. Welch ,  Ronald P. Vogl ,  Samuel F. Yana Motta

IPC: C09K5/00 ,  C11D3/24

CPC classification number: C09K5/044 ,  C07C17/42 ,  C09K5/045 ,  C09K2205/126 ,  C07C21/18 ,  C07C19/16

Abstract: Provided is a composition comprising (a) at least one halogenated compound selected from the group consisting of C3-C5 hydrofluoroolefin, CF3I, and combinations thereof, and (b) an effective stabilizing amount of a sesquiterpene selected from the group consisting of farnesol, farnesene, and mixtures thereof.

Abstract translation: 提供了一种组合物，其包含（a）至少一种选自C 3 -C 5氢氟烯烃，CF 3 I及其组合的卤代化合物，和（b）有效稳定量的倍半萜烯，选自法呢醇，法呢烯 ，及其混合物。

公开(公告)号：US20100044620A1

公开(公告)日：2010-02-25

申请号：US12519280

申请日：2007-12-17

Applicant: Wissam Rached

Inventor： Wissam Rached

IPC: C09K5/00

CPC classification number: C09K5/045 ,  C07C19/08 ,  C07C19/16 ,  C07C21/18 ,  C07C21/185 ,  C09K2205/106

Abstract: The invention relates to compositions that can be used as refrigerants. More specifically, the invention relates to compositions having a very low contribution to the greenhouse effect, which can be used in the cooling and production of conditioned air. The GWP of the inventive compositions is preferably at most equal to 150.

Abstract translation: 本发明涉及可用作制冷剂的组合物。 更具体地，本发明涉及对温室效应贡献很低的组合物，其可用于冷却和生产调节空气。 本发明组合物的GWP优选至多等于150。

公开(公告)号：US20090312517A1

公开(公告)日：2009-12-17

申请号：US12519649

申请日：2007-12-27

Applicant: Yu Yang ,  George G.I. Moore

Inventor： Yu Yang ,  George G.I. Moore

IPC: C08G63/00 ,  C08G61/00 ,  C08G75/00

CPC classification number: C08F2/38 ,  C07C17/275 ,  C07C19/14 ,  C07C19/16 ,  C07C43/126 ,  C07C69/63 ,  C07C309/82 ,  C07C311/09 ,  C08F8/10 ,  C08F8/12 ,  C08F8/14 ,  C08F120/24 ,  C08F120/36 ,  C08F220/24 ,  C08G18/2885 ,  C09D175/04 ,  D06M15/256 ,  Y10T428/3154 ,  C08F110/02

Abstract: A process comprises combining in a batchwise, semi-continuous, or continuous manner, or a combination thereof, in the presence of at least one free radical initiator, and at a temperature sufficient to cause the initiator to fragment to form free radicals, (a) at least one telogen selected from (1) fluoroalkyl halides that comprise at least one halomethylene moiety (—CHX—) and, optionally, at least one non-fluorine heteroatom, and (2) perfluoroalkyl halides that comprise at least one halofluoromethylene moiety (—CFX—) and at least one non-halogen heteroatom, the halides being selected from iodides and bromides; and (b) ethylene; the telogen and the ethylene being combined in total amounts such that the number of moles of ethylene per mole of telogen is at least about 4.

Abstract translation: 一种方法包括在分批，半连续或连续方式或其组合中，在至少一种自由基引发剂存在下，和足以引发引发剂片段形成自由基的温度下（ ）至少一个选自（1）包含至少一个卤代亚甲基部分（-CHX-）和任选的至少一个非氟杂原子的氟代烷基卤化物的起始物，和（2）包含至少一个卤氟亚甲基部分的全氟烷基卤化物 -CFX-）和至少一个非卤素杂原子，所述卤化物选自碘化物和溴化物; 和（b）乙烯; 季戊四醇和乙烯的总量相结合，使得每摩尔环糊精的乙烯摩尔数至少约为4。

公开(公告)号：US07601878B2

公开(公告)日：2009-10-13

申请号：US11723115

申请日：2007-03-16

Applicant: Tatsuya Hirata ,  Kouzou Noda ,  Jun Miki

Inventor： Tatsuya Hirata ,  Kouzou Noda ,  Jun Miki

IPC: C07C17/38 ,  C07C17/269 ,  C07C17/278

CPC classification number: B01J8/0055 ,  B01J8/222 ,  B01J38/00 ,  B01J2208/00176 ,  B01J2208/00867 ,  C07C17/278 ,  C07C17/38 ,  Y02P20/582 ,  Y02P20/584 ,  C07C19/16

Abstract: A solid catalyst used in, for example, production of a perfluoroalkyl iodide telomer is effectively and continuously recovered and the recovered catalyst is continuously recycled to the reactor for reuse. A slurry containing a reaction product and the catalyst is drawn from the reaction system, and the catalyst in the drawn slurry is classified by means of a hydrocyclone, whereby a high-concentration slurry whose catalyst concentration is higher than that of the drawn slurry and a low-concentration slurry whose catalyst concentration is lower than that of the drawn slurry are obtained, and the high-concentration slurry is recycled to the reaction system.

Abstract translation: 用于例如生产全氟烷基碘调节剂的固体催化剂被有效且连续地回收，并将回收的催化剂连续再循环到反应器中再使用。 从反应体系中抽出含有反应产物和催化剂的浆料，并且通过水力旋流器对拉伸浆料中的催化剂进行分级，由此得到催化剂浓度高于拉制浆料的高浓度浆料和 得到催化剂浓度低于所提取的浆液的低浓度浆料，将高浓度浆液再循环至反应体系。

公开(公告)号：US20090137773A1

公开(公告)日：2009-05-28

申请号：US11922980

申请日：2006-07-28

Applicant: Andrew Jackson ,  Vimal Sharma ,  Bradley E. Edwards ,  Janet Boggs ,  Victoria Hedrick ,  Stephan Brandstadter ,  John Chien ,  Edward Norman ,  Robert Kaufman ,  Bruno Ameduri ,  George K. Kostov

Inventor： Andrew Jackson ,  Vimal Sharma ,  Bradley E. Edwards ,  Janet Boggs ,  Victoria Hedrick ,  Stephan Brandstadter ,  John Chien ,  Edward Norman ,  Robert Kaufman ,  Bruno Ameduri ,  George K. Kostov

IPC: C08G75/20 ,  C07C317/04 ,  C07C311/01 ,  C07F9/09 ,  C07C31/38 ,  C07C19/08

CPC classification number: C07C21/18 ,  A62D1/0085 ,  C07C19/075 ,  C07C19/10 ,  C07C19/16 ,  C07C22/02 ,  C07C43/137 ,  C07C69/653 ,  C07C311/09 ,  C07C317/18 ,  C07F9/091 ,  C07F9/14 ,  C11D1/004 ,  C11D3/0026 ,  C11D3/0031

Abstract: Compositions and methods for making compositions such as RF(Rτ)nQ are provided. The RF group can include at least two —CF3 groups, the Rτ group can be a group having at least two carbons, n can be at least 1, and the Q group can include one or more atoms of the periodic table of elements. RF-intermediates (RF(RT)nQg); Surfactants (RF(RT)nQs); Foam stabilizers (RF(RT)IIQFS); Metal complexes (RF(RT)IIQMC); Phosphate ester (RF(RT)HQPE); Polymers (RF(RT)IIQMU); Monomers (RF(RT)IIQM); Urethanes (RF(Rτ)nQu); and/or Glycols (RF(RT)IIQH) and methods for making the same are provided.

Abstract translation: 提供了组合物如RF（Rtau）nQ的组合物和方法。 RF基团可以包括至少两个-CF 3基团，Rtau基团可以是具有至少两个碳原子的基团，n可以至少为1，并且Q基团可以包括元素周期表的一个或多个原子。 RF-中间体（RF（RT）nQg）; 表面活性剂（RF（RT）nQs）; 泡沫稳定剂（RF（RT）IIQFS）; 金属络合物（RF（RT）IIQMC）; 磷酸酯（RF（RT）HQPE）; 聚合物（RF（RT）IIQMU）; 单体（RF（RT）IIQM）; 聚氨酯（RF（Rtau）nQu）; 和/或二醇（RF（RT）IIQH）及其制备方法。

公开(公告)号：US20080097131A1

公开(公告)日：2008-04-24

申请号：US12001269

申请日：2007-12-11

Applicant: Alexander Shtarov ,  Jon Howell

Inventor： Alexander Shtarov ,  Jon Howell

IPC: C07C19/16

CPC classification number: C07B59/001 ,  C07B2200/05 ,  C07C19/16 ,  C07C21/18 ,  C07C41/18 ,  C07C43/123 ,  C07C51/15 ,  C07C51/60 ,  C07C51/62 ,  C07C309/06 ,  C07C53/21 ,  C07C53/50 ,  C07C59/135

Abstract: Various 13C and 14C carbon labeled compounds Rf—bCF(U)y(T)z  Formula 1A or Rf—bCF2bCF(U)y(T)z  Formula 1B wherein Rf is a linear or branched perfluoroalkyl radical Z(CmF2m)—, m is 1, 3 to 20, or a mixture thereof; Z is F when m is 1, and Z is F, Cl, or H when m is 3 to 20 or a mixture thereof; b is 13 or 14; y is 1, and z is 0 or 1; and when y and z are each 1, U is F, and T is selected from the group consisting of monovalent radicals —X wherein X is I or Br, —CH2—CH2—X, —CH═CH2, —CH2—CH2—OH, —CH2—COOH, —CH2OH, —bCH2OH, —COOH, —bCOOH, —O—CF(CF3)—C(O)F, —O—CF(CF3)—X, —SO2Y wherein Y is H, F or Cl, and —SO3H; and when y is 1, and z is 0, U is selected from the group consisting of divalent radicals ═CH—COOH, ═CH—CH2—OH, and =0, are disclosed, and a process for their preparation which selectively introduces 13C and 14C carbon labels into a fluoroalkyl chain.

Abstract translation: 各种 13 C和14 C碳标记的化合物<？in-line-formula description =“In-line Formulas”end =“lead”？> R f 式（1A）或<β在线公式描述=“In” -line公式“end =”tail“？> <？in-line-formula description =”In-line Formulas“end =”lead“？> R CF（U）y（T）>>>>> formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas formulas>>>>>>>>>>>>>>>>>>> formulas formulas formulas formulas formulas description =“In-line Formulas”end =“tail”？>其中R f是直链或支链的全氟烷基Z（C m 2 F 2 m） SUB-） - ，m为1,3至20，或其混合物; 当m为1时，Z为F，当m为3至20时Z为F，Cl或H或其混合物; b为13或14; y为1，z为0或1; 当y和z各自为1时，U为F，T选自单价基团-X，其中X为I或Br，-CH 2 -CH 2， -X，-CH-CH 2，-CH 2 -CH 2 -OH，-CH 2 CH 2， SO 2 -COOH，-CH 2 OH， - CH 2 CH 2 OH，-COOH， - CO 2 COOH ，-O-CF（CF 3） - C（O）F，-O-CF（CF 3） - X，-SO 2

公开(公告)号：US20070282115A1

公开(公告)日：2007-12-06

申请号：US10587724

申请日：2005-01-28

Applicant: Janet Boggs ,  Stephan Brandstadter ,  John Chien ,  Mitchel Cohn ,  E. Edwards ,  Vicki Hedrick ,  Andrew Jackson ,  Gregory Leman ,  Bruno Ameduri ,  George Kostov

Inventor： Janet Boggs ,  Stephan Brandstadter ,  John Chien ,  Mitchel Cohn ,  E. Edwards ,  Vicki Hedrick ,  Andrew Jackson ,  Gregory Leman ,  Bruno Ameduri ,  George Kostov

IPC: C07C19/08 ,  C07C19/16 ,  C07C21/18 ,  C07C31/38 ,  C07C43/205 ,  C07C43/215 ,  C07C69/62 ,  C07C69/635 ,  C07C69/78 ,  C07D303/02 ,  C07D307/935

CPC classification number: C07C17/278 ,  C07C19/08 ,  C07C19/10 ,  C07C19/14 ,  C07C19/16 ,  C07C21/18

Abstract: Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohols, reacting olefins and a saturated compounds, reacting reactants having at least two —CF3 groups with reactants having cyclic groups. RF-compositions such as RF-intermediates, RF-surfactants, RF-monomers, RF-monomer units, RF-metal complexes, RF-phosphate esters, RF-glycols, RF-urethanes, and/or RF-foam stabilizers. The RF portion can include at least two —CF3 groups, at least three —CF3 groups, and/or at least two —CF3 groups and at least two —CH2— groups. Detergents, emulsifiers, paints, adhesives, inks, wetting agents, foamers, and defoamers including the RF-surfactant composition are provided. Acrylics, resins, and polymers are provided that include a RF-monomer unit. Compositions are provided that include a substrate having a RF-composition thereover. Aqueous Film Forming Foam (“AFFF”) formulations are provided that can include RF-surfactants and/or RF-foam stabilizers are provided.

Abstract translation: 提供了生产方法和系统，其包括卤代化合物，脱卤化合物，醇反应，烯烃与饱和化合物的反应，使具有至少两个-CF 3 N 3基团的反应物与具有环状基团的反应物反应。 R F - 如R 1 - 中间体，R 1 F - 表面活性剂，R 1 F - 单体，R 单 - 单体单元，R 1 F - 金属络合物，R 1 F - 磷酸酯，R 1 - 二醇， R F - 氨基甲酸酯，和/或R F - 泡沫稳定剂。 R 1 F 3部分可以包括至少两个-CF 3 N 3基团，至少三个-CF 3 N 3基团和/或至少两个 - CF 3个基团和至少两个-CH 2 - 基团。 提供了洗涤剂，乳化剂，油漆，粘合剂，油墨，润湿剂，起泡剂和消泡剂，包括R 1 F - 表面活性剂组合物。 提供了包括R 1 F单体单元的丙烯酸树脂，树脂和聚合物。 提供了包含其上具有R 1 -F 3 - 组成的底物的组合物。 提供了可以包括R 1 F - 表面活性剂的水性成膜泡沫（“AFFF”）制剂和/或提供的R 3 F泡沫体稳定剂。