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公开(公告)号：US20110036431A1
公开(公告)日：2011-02-17
申请号：US12540875
申请日：2009-08-13
Applicant: Kwangyeol Lee
Inventor： Kwangyeol Lee
CPC classification number: F16K99/0001 , F16K99/0019 , F16K99/004 , Y10T137/2196 , Y10T428/2991 , Y10T428/2993 , Y10T428/2998
Abstract: Compositions, systems and methods for using a nanoparticle composite to act as a valve within a microfluidic conduit to regulate fluid flow therethrough are provided. The nanoparticle composite includes a core having magnetic particles and Au particles and includes a hydrogel coating surrounding the core. The size of the nanoparticle composite is controlled by causing the hydrogel coating to lose water or absorb water, thus decreasing or increasing the size of the nanoparticle composite within the microfluidic conduit.
Abstract translation: 提供了使用纳米颗粒复合材料作为微流体导管内的阀以调节流过其中的流体的组合物，系统和方法。 纳米颗粒复合物包括具有磁性颗粒和Au颗粒的芯，并且包括围绕芯的水凝胶涂层。 纳米颗粒复合物的尺寸通过使水凝胶涂层失去水或吸收水来控制，从而降低或增加微流体导管内的纳米颗粒复合材料的尺寸。
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公开(公告)号：US20100300550A1
公开(公告)日：2010-12-02
申请号：US12839063
申请日：2010-07-19
Applicant: James Allen Mathias , G. Bradley Chadwell , Dongming Qiu , Anna Lee Y.Tonkovich , Steven T. Perry , Matthew B. Schmidt , Sean P. Fitzgerald , David J. Hesse , Thomas D. Yuschak , Bin Yang
Inventor： James Allen Mathias , G. Bradley Chadwell , Dongming Qiu , Anna Lee Y.Tonkovich , Steven T. Perry , Matthew B. Schmidt , Sean P. Fitzgerald , David J. Hesse , Thomas D. Yuschak , Bin Yang
CPC classification number: F16L41/02 , B01J19/0093 , B01J35/04 , B01J2219/00869 , B01J2219/00891 , C01B3/384 , C01B2203/0233 , C01B2203/0811 , C01B2203/0822 , F28D7/0066 , F28D9/0093 , F28F3/12 , F28F7/02 , F28F2260/02 , Y02P20/128 , Y02P20/52 , Y10T137/0318 , Y10T137/6579 , Y10T137/87153 , Y10T137/87249
Abstract: Provided is a process and device for exchanging heat energy between three or more streams in a microchannel heat exchanger which can be integrated with a microchannel reactor to form an integrated microchannel processing unit. The combining of a plurality of integrated microchannel devices to provide the benefits of large-scale operation is enabled. In particular, the microchannel heat exchanger enables flexible heat transfer between multiple streams and total heat transfer rates of about 1 Watt or more per core unit volume expressed as W/cc.
Abstract translation: 提供了一种用于在微通道热交换器中的三个或更多个流之间交换热能的过程和装置，其可以与微通道反应器集成以形成集成的微通道处理单元。 实现了多个集成微通道装置的组合以提供大规模操作的优点。 特别地，微通道热交换器使得能够在多个流之间实现柔性热传递，并且以W / cc表示的每单位体积的约1瓦或更高的总传热速率。
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公开(公告)号：US07802591B2
公开(公告)日：2010-09-28
申请号：US10534592
申请日：2003-11-14
Applicant: David Anthony Barrow , Nicola Harries , Tyrone Gwyn Jones , Kostas Bouris
Inventor： David Anthony Barrow , Nicola Harries , Tyrone Gwyn Jones , Kostas Bouris
CPC classification number: B01F13/0071 , B01L3/502784 , B01L2200/0636 , B01L2200/0673 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2300/0887 , B01L2400/0409 , B01L2400/0415 , B01L2400/0427 , B01L2400/0487 , B82Y10/00 , B82Y30/00 , Y10T137/2076 , Y10T137/2224 , Y10T137/8593
Abstract: A microfluidic device comprises first and second inlet passages (13) for respective immiscible fluids, these inlet passages merging into a third passage (8) along which the two fluids flow under parallel laminar flow conditions, the third passage being formed with a constriction or other discontinuity (9) causing the two fluids to form into a flow of alternate segments.
Abstract translation: 微流体装置包括用于各自不混溶流体的第一和第二入口通道（13），这些入口通道合并成第三通道（8），两个流体在该第三通道（8）沿着平行的层流条件流动，第三通道形成有收缩或其它 不连续（9）导致两种流体形成交替段的流动。
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公开(公告)号：US20090165872A1
公开(公告)日：2009-07-02
申请号：US12226416
申请日：2006-06-02
Applicant: Shuji Moriya , Hideki Nagaoka , Tsuneyuki Okabe , Hiroshi Itafuji , Hiroki Doi , Minoru Ito
Inventor： Shuji Moriya , Hideki Nagaoka , Tsuneyuki Okabe , Hiroshi Itafuji , Hiroki Doi , Minoru Ito
IPC: F15C1/06
CPC classification number: F17D1/04 , Y10T137/87177 , Y10T137/87885
Abstract: A gas supply unit and a gas supply system that are small-sized and inexpensive. The gas supply unit is installed on operation gas conveyance pipeline and has fluid control devices communicated via flow path blocks and controlling operation gas. The gas supply unit has the first flow path block, to one side of which an inlet open/close valve included in the fluid control devices is attached, and also has the second flow path block, to one side of which a purge valve included in the fluid control devices is attached. The first flow path block and the second flow path block are layered in the direction perpendicular to the conveyance direction of the operation gas. The inlet open/close valve and the purge valve are arranged between a mass flow controller installed on the operation gas conveyance pipeline and an installation surface where the unit is installed.
Abstract translation: 气体供给单元和气体供给系统，其尺寸小且便宜。 气体供应单元安装在操作气体输送管道上，并具有通过流路块连接并控制操作气体的流体控制装置。 气体供应单元具有第一流路块，其一侧包括在流体控制装置中的入口打开/关闭阀，并且还具有第二流路块，其一侧包括一个净化阀 流体控制装置被连接。 第一流路块和第二流路块在与操作气体的输送方向垂直的方向上分层。 入口打开/关闭阀和净化阀布置在安装在操作气体输送管线上的质量流量控制器和安装单元的安装表面之间。
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公开(公告)号：US07482585B2
公开(公告)日：2009-01-27
申请号：US11434253
申请日：2006-05-16
Applicant: Yasuhiro Sando , Akihisa Nakajima , Kusunoki Higashino
Inventor： Yasuhiro Sando , Akihisa Nakajima , Kusunoki Higashino
CPC classification number: B01L3/565 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2200/028 , B01L2300/044 , B01L2300/0672 , B01L2300/0816 , B01L2300/0887 , B01L2400/0439 , G01N2035/00158 , Y10T137/87877
Abstract: A testing chip includes (1) a first chip having a micro flow path that stores reagent; upstream-side opening provided on upstream-side of the micro flow path; downstream-side opening provided on downstream-side of the micro flow path; and one or more sealing members in a small thickness stuck to at least one surface of the first chip to seal the upstream-side opening and the downstream-side opening until the testing chip is used and (2) a second chip having a micro flow path for mixing and reaction between reagent and a specimen and detecting the reaction; and an opening provided on upstream-side of the micro flow path, wherein, when the testing chip is used, the first and second chips are superimposed on each other so that the downstream-side opening of the first chip and the opening of the second chip are positioned on each other.
Abstract translation: 测试芯片包括（1）具有存储试剂的微流路的第一芯片; 设置在微流路的上游侧的上游侧开口; 设置在微流路的下游侧的下游侧开口; 并且将一个或多个小密封件粘贴到第一芯片的至少一个表面上以密封上游侧开口和下游侧开口，直到使用测试芯片，以及（2）具有微流量的第二芯片 试剂和样品之间进行混合和反应的途径，检测反应; 以及设置在微流路的上游侧的开口，其中，当使用测试芯片时，第一和第二芯片彼此重叠，使得第一芯片的下游侧开口和第二芯片的打开 芯片彼此定位。
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Patent Agency Ranking
公开(公告)号：US20070215224A1
公开(公告)日：2007-09-20
申请号：US11276772
申请日：2006-03-14
Applicant: Toshiharu Furukawa , Mark Hakey , Steven Holmes , David Horak , Charles Koburger
Inventor： Toshiharu Furukawa , Mark Hakey , Steven Holmes , David Horak , Charles Koburger
IPC: F15C1/06
CPC classification number: F15C1/06 , F04B43/043 , F15C5/00 , F16K99/0001 , F16K99/0015 , F16K99/0051 , F16K2099/0074 , F16K2099/0094 , Y10T29/49236 , Y10T29/49412 , Y10T137/2224
Abstract: Micro-valves and micro-pumps and methods of fabricating micro-valves and micro-pumps. The micro-valves and micro-pumps include electrically conductive diaphragms fabricated from electrically conductive nano-fibers. Fluid flow through the micro-valves and pumping action of the micro-pumps is accomplished by applying electrostatic forces to the electrically conductive diaphragms.
Abstract translation: 微型阀门和微型泵以及制造微型阀门和微型泵的方法。 微型阀和微型泵包括由导电纳米纤维制成的导电隔膜。 通过微型阀的流体流动和微型泵的泵送作用是通过将静电力施加到导电隔膜来实现的。
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公开(公告)号：US20070113908A1
公开(公告)日：2007-05-24
申请号：US11561149
申请日：2006-11-17
Applicant: L. Lee , Chunmeng Lu , Yi-Je Juang
Inventor： L. Lee , Chunmeng Lu , Yi-Je Juang
IPC: F15C1/06
CPC classification number: F16K99/0017 , B01L3/502738 , B01L2300/0806 , B01L2300/166 , B01L2400/0409 , B01L2400/0688 , F16K99/0001 , F16K99/0034 , F16K99/0057 , F16K2099/0084 , Y10T137/2224
Abstract: A valve is provided for use in a microfluidic platform. The valve is preferably a superhydrophobic fishbone valve that comprises a channel and at least one branch in continuous contact with the channel. The channel has two sidewalls, an inlet, and an outlet. The branch extends outwardly and substantially perpendicularly from each sidewall of the channel. In further embodiments, the number of branches is from one to five. The sidewalls and the walls of the branch(es) preferably have a fluorine coating. The valve retains superhydrophobicity even after exposure to a protein solution.
Abstract translation: 提供用于微流体平台的阀。 阀优选地是超疏水鱼骨阀，其包括通道和与通道连续接触的至少一个分支。 通道有两个侧壁，一个入口和一个出口。 分支从通道的每个侧壁向外且基本垂直地延伸。 在另外的实施例中，分支数为1至5。 分支的侧壁和壁优选具有氟涂层。 即使在暴露于蛋白质溶液之后，阀也保持超疏水性。
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公开(公告)号：US07207345B2
公开(公告)日：2007-04-24
申请号：US10528576
申请日：2003-09-23
Applicant: John Matthew Somerville
Inventor： John Matthew Somerville
CPC classification number: B01F13/0066 , B01F5/0641 , B01F13/0093 , Y10T137/0329 , Y10T137/0352 , Y10T137/0396 , Y10T137/2224
Abstract: A single layer fluid routing device comprising a first channel having a cross-section of a first aspect ratio and a first depth; a second channel having a second cross-section of a second different aspect ratio and a second different depth; wherein the second channel intersects with the first channel from a first point to a second point, the first and second points having different offsets relative to the cross-section of the first channel.
Abstract translation: 单层流体路线装置，其包括具有第一纵横比和第一深度的横截面的第一通道; 具有第二不同纵横比和第二不同深度的第二横截面的第二通道; 其中所述第二通道与所述第一通道相交，从第一点到第二点，所述第一和第二点相对于所述第一通道的横截面具有不同的偏移。
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公开(公告)号：US07156118B2
公开(公告)日：2007-01-02
申请号：US10525400
申请日：2003-08-21
Applicant: Gregor Ocvirk , Carlo Effenhauser , Karl-Heinz Koelker
Inventor： Gregor Ocvirk , Carlo Effenhauser , Karl-Heinz Koelker
CPC classification number: F16K51/00 , B01F7/16 , B01F13/0059 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/0086 , B01L3/502707 , B01L2200/12 , B01L2300/0681 , B01L2300/0874 , B01L2300/0887 , B01L2400/084 , Y10T137/0329 , Y10T137/0352 , Y10T137/0491 , Y10T137/2224
Abstract: The invention relates to the technical field of microfluidic channel structures. The invention discloses a microfluidic channel system with a high aspect ratio as well as a process for producing the microfluidic system. The process according to the invention enables the production of channel structures with aspect ratios of any magnitude without the process being limited by the manufacturing conditions to certain materials for the channel system. The channel system can thus be optimally adapted to a desired field of application.
Abstract translation: 本发明涉及微流体通道结构的技术领域。 本发明公开了具有高纵横比的微流体通道系统以及用于生产微流体系统的方法。 根据本发明的方法使得能够生产具有任何幅度的纵横比的通道结构，而不会使制造条件限制于通道系统的某些材料。 因此，信道系统可以最佳地适应于期望的应用领域。
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公开(公告)号：US20060157129A1
公开(公告)日：2006-07-20
申请号：US10528576
申请日：2003-09-23
Applicant: John Somerville
Inventor： John Somerville
IPC: F15C1/06
CPC classification number: B01F13/0066 , B01F5/0641 , B01F13/0093 , Y10T137/0329 , Y10T137/0352 , Y10T137/0396 , Y10T137/2224
Abstract: A single layer fluid routing device comprising a first channel having a cross-section of a first aspect ratio and a first depth; a second channel having a second cross-section of a second different aspect ratio and a second different depth; wherein the second channel intersects with the first channel from a first point to a second point, the first and second points having different offsets relative to the cross-section of the first channel.
Abstract translation: 单层流体路线装置，其包括具有第一纵横比和第一深度的横截面的第一通道; 具有第二不同纵横比和第二不同深度的第二横截面的第二通道; 其中所述第二通道与所述第一通道相交，从第一点到第二点，所述第一和第二点相对于所述第一通道的横截面具有不同的偏移。
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