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    Systems and methods for performing peritoneal dialysis
    71.
    发明授权
    Systems and methods for performing peritoneal dialysis 有权
    进行腹膜透析的系统和方法

    公开(公告)号：US07867214B2

    公开(公告)日：2011-01-11

    申请号：US10623316

    申请日：2003-07-17

    申请人： Robert W. Childers ,  David S. Brown ,  Ramesh Wariar ,  Sujatha Karoor ,  Shahid Din ,  Leo Martis ,  Cody Buchmann ,  Paul Soltys

    发明人： Robert W. Childers ,  David S. Brown ,  Ramesh Wariar ,  Sujatha Karoor ,  Shahid Din ,  Leo Martis ,  Cody Buchmann ,  Paul Soltys

    IPC分类号： A61M5/32 ,  A61M37/00

    CPC分类号： A61M1/1696 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/166 ,  A61M1/28 ,  A61M1/284 ,  A61M1/285 ,  A61M1/287 ,  A61M1/288 ,  A61M2202/0413 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2205/3327

    摘要： In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.

    摘要翻译： 在本发明的腹膜透析实施方案中，来自患者腹膜腔的消耗的透析液沿着患者回路通过具有将废物组分与废透析液分离的膜的透析器，其中患者回路将新鲜透析液返回到患者的腹膜 腔。 废物组分在第二再生回路中被带走到吸收废物组分的再生单元或吸附剂盒。 再生单元除去透析器从患者回路中除去的不需要的成分，例如过量的水（超滤液或UF），毒素和代谢废物。 可以通过系统将诸如葡萄糖和电解质等组分加入到透析液中。 这些添加剂有助于维持患者中适当的渗透梯度进行透析，并为患者提供必要的化合物。

    PERITONEAL DIALYSATE
    73.
    发明申请
    PERITONEAL DIALYSATE 审中-公开
    皮肤透析

    公开(公告)号：US20100187476A1

    公开(公告)日：2010-07-29

    申请号：US12733163

    申请日：2007-08-15

    申请人： Yasumi Yugari ,  Tsutomu Sanaka

    发明人： Yasumi Yugari ,  Tsutomu Sanaka

    IPC分类号： C09K3/00

    CPC分类号： A61M1/287 ,  A61K31/185 ,  A61K31/7016 ,  A61K45/06 ,  A61K2300/00

    摘要： This invention provides a safe and highly stable peritoneal dialysate, which causes neither peritoneal membrane disorders nor peritoneal sclerosis associated with frequently repeated peritoneal dialysis treatment, which can protect residual renal functions in chronic renal failure, which inhibits the progress of renal damage over a long period of time, and which enables peritoneal dialysis treatment of diabetic patients. This peritoneal dialysate contains 0.05 to 3.5 w/v % of taurine and 0.1 to 6.5 w/v % of trehalose as osmotic agents and has a pH value adjusted between 6.5-7.5.

    摘要翻译： 本发明提供了一种安全和高度稳定的腹膜透析液，其既不引起腹膜膜病变，也不引起与经常重复腹膜透析治疗相关的腹膜硬化症，其可以保护慢性肾功能衰竭中的残留肾功能，其长期抑制肾损伤的进展 的时间，并且其能够进行糖尿病患者的腹膜透析治疗。 该腹膜透析液含有0.05〜3.5w / v％的牛磺酸和0.1〜6.5w / v％的海藻糖作为渗透剂，pH值调节在6.5〜7.5之间。

    CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE
    74.
    发明申请
    CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE 审中-公开
    基于碳氢化合物的含有谷氨酰胺残基的透析液

    公开(公告)号：US20100099628A1

    公开(公告)日：2010-04-22

    申请号：US12529537

    申请日：2008-03-03

    申请人： Christoph Aufricht

    发明人： Christoph Aufricht

    IPC分类号： A61K38/08 ,  A61K38/05 ,  A61K38/06 ,  A61K38/07 ,  A61K31/198 ,  A61P35/00

    CPC分类号： A61K38/05 ,  A61K31/198 ,  A61K38/06 ,  A61K38/07 ,  A61K38/08 ,  A61M1/287

    摘要： The present invention relates to a carbohydrate-based peritoneal dialysis fluid, containing a compound selected from the group consisting of glutamine, preferably L-glutamine, a dipeptide capable of releasing glutamine, L-glutamine in free form, preferably selected from the group consisting of glutaminyl-glycine, glycinyl-glutamine, glutaminyl-alanine, alanyl-glutamine an oligopeptide consisting of two to seven glutamine, preferably L-glutamine residues, and mixtures thereof. The peritoneal dialysis fluids of the present invention are useful for inhibition of technical failure in a person undergoing peritoneal dialysis treatment.

    摘要翻译： 本发明涉及一种基于碳水化合物的腹膜透析液，其含有选自谷氨酰胺，优选L-谷氨酰胺，能够释放谷氨酰胺的二肽，游离形式的L-谷氨酰胺，优选选自由以下组成的组的化合物： 谷氨酰胺 - 甘氨酸，甘氨酰 - 谷氨酰胺，谷氨酰胺基 - 丙氨酸，丙氨酰 - 谷氨酰胺，由2至7个谷氨酰胺，优选L-谷氨酰胺残基组成的寡肽及其混合物。 本发明的腹膜透析液可用于抑制接受腹膜透析治疗的人的技术失败。

    DIALYSIS SYSTEM AND MACHINE HAVING THERAPY PRESCRIPTION RECALL
    77.
    发明申请
    DIALYSIS SYSTEM AND MACHINE HAVING THERAPY PRESCRIPTION RECALL 有权
    DIALYSIS系统和具有治疗方法的机器

    公开(公告)号：US20100010428A1

    公开(公告)日：2010-01-14

    申请号：US12170230

    申请日：2008-07-09

    申请人： Anping Yu ,  Robert W. Childers ,  Borut Cizman

    发明人： Anping Yu ,  Robert W. Childers ,  Borut Cizman

    IPC分类号： A61M1/28

    CPC分类号： G06F19/3456 ,  A61M1/1601 ,  A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2209/01 ,  B01D61/32 ,  G06F19/00 ,  G06F19/3418

    摘要： In one embodiment an automated peritoneal dialysis (“APD”) machine includes: at least one pump; a logic implementer storing a plurality of therapy prescriptions by which to operate the at least one pump, each therapy prescription pre-approved for a particular patient; and an input device operating with the logic implementer to allow the patient to select one of the therapy prescriptions for a particular therapy. In another embodiment, the input device operating with the logic implementer allows a doctor/clinician to select or approve one of the therapy prescriptions to be run on the APD machine. In a further embodiment, the logic implementer is programmed to select or suggest one of the therapy prescriptions to be run on the is APD machine.

    摘要翻译： 在一个实施例中，自动腹膜透析（“APD”）机器包括：至少一个泵; 存储多个用于操作所述至少一个泵的治疗处方的逻辑实现器，为特定患者预先批准的每个治疗处方; 以及与逻辑实现者一起操作的输入设备，以允许患者选择用于特定治疗的治疗处方之一。 在另一个实施例中，与逻辑实施器一起操作的输入设备允许医生/临床医生选择或批准在APD机器上运行的治疗处方之一。 在另一实施例中，逻辑实现器被编程为选择或建议要在APD机器上运行的治疗处方之一。

    DIALYSIS SYSTEM HAVING REGIMEN GENERATION METHODOLOGY
    79.
    发明申请
    DIALYSIS SYSTEM HAVING REGIMEN GENERATION METHODOLOGY 有权
    具有计量生成方法的透析系统

    公开(公告)号：US20100010424A1

    公开(公告)日：2010-01-14

    申请号：US12170184

    申请日：2008-07-09

    申请人： Anping Yu ,  Robert W. Childers ,  Edward F. Vonesh ,  Borut Cizman

    发明人： Anping Yu ,  Robert W. Childers ,  Edward F. Vonesh ,  Borut Cizman

    IPC分类号： A61M1/28

    CPC分类号： A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/502 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/60 ,  G16H50/50 ,  Y10S706/924

    摘要： A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input.

    摘要翻译： 腹膜透析系统包括逻辑实现器，其被配置为：（i）接受至少一个治疗目标输入; （ii）接受至少一个患者运输特征输入; （iii）接受至少一个解决方案输入; （iv）接受至少一个流体体积输入; （v）接受至少一个治疗时间输入，所述输入（ii）至（v）中的至少一个包括输入范围; 和（vi）使用（ii），（iii），（iv）和（v）的输入产生每种治疗方案，包括满足至少一种治疗目标输入的至少一个输入范围内的每种可能性 。

    DISTRIBUTED PROCESSING SYSTEM AND METHOD FOR DIALYSIS MACHINES
    80.
    发明申请
    DISTRIBUTED PROCESSING SYSTEM AND METHOD FOR DIALYSIS MACHINES 有权
    分布式处理系统和DIALYSIS MACHINES的方法

    公开(公告)号：US20090312694A1

    公开(公告)日：2009-12-17

    申请号：US12137459

    申请日：2008-06-11

    申请人： John Bedingfield ,  Benjamin Kellam ,  Ronald D. Baerg ,  Gideon Hecht

    发明人： John Bedingfield ,  Benjamin Kellam ,  Ronald D. Baerg ,  Gideon Hecht

    IPC分类号： A61M1/28

    CPC分类号： A61M1/1656 ,  A61M1/1664 ,  A61M1/167 ,  A61M1/28 ,  A61M1/287 ,  A61M2205/3368 ,  A61M2205/50 ,  A61M2205/502

    摘要： A dialysis machine includes a control unit having a user interface; a heater(s) located separate from the control unit; a supervisory processor located with the control unit; a delegate control processor located with the heater(s), the delegate control processor in communication with the supervisory processor and configured to receive load cell, heater(s) plate and supply bag temperature sensor inputs; and a sub-delegate heater(s) processor in communication with the control processor and configured to control power to the heater(s). The machine can also include primary and secondary monitoring processors that perform a safety check to the control processing and monitor the load cell.

    摘要翻译： 透析机包括具有用户界面的控制单元; 与控制单元分离的加热器; 位于控制单元的监控处理器; 位于加热器的代表控制处理器，委托控制处理器与监控处理器通信并配置成接收负载传感器，加热器板和供应袋温度传感器输入; 以及与控制处理器通信并被配置为控制加热器的电力的子代表加热器处理器。 该机器还可以包括执行安全检查以控制处理和监测称重传感器的主要和次要监视处理器。