公开(公告)号：US10076628B2

公开(公告)日：2018-09-18

申请号：US13820620

申请日：2011-09-02

Applicant: Gordon Joseph Malouf ,  Liam Holley ,  Paul Jan Klasek

Inventor： Gordon Joseph Malouf ,  Liam Holley ,  Paul Jan Klasek

IPC: A62B9/02 ,  A61M16/08 ,  A61M16/00 ,  A61M16/06 ,  A61M16/04 ,  A61M16/20 ,  A61M16/12 ,  A61M16/16

CPC classification number: A61M16/0808 ,  A61M16/0057 ,  A61M16/04 ,  A61M16/0666 ,  A61M16/0683 ,  A61M16/0833 ,  A61M16/0875 ,  A61M16/12 ,  A61M16/16 ,  A61M16/20 ,  A61M16/202 ,  A61M16/208 ,  A61M2202/0208 ,  A61M2202/025 ,  A61M2202/0266

Abstract: Components for a respiratory treatment apparatus that is capable of providing a humidified respiratory treatment permit a reduction in condensation in a patient interface and/or its gas delivery tubing. In some embodiments, a rainout valve that may be an integrated component of a humidifier output aperture, or coupled thereto, may reduce condensation with a vapor barrier operable to selectively block and permit humidified gas transfer from the humidifier. For example, the barrier may be operable to open in response to a flow of pressurized breathable gas that may be generated by a flow generator of the respiratory treatment apparatus. In the absence of such a generation of pressurized flow, the barrier may prevent a transfer of the humidified gas such as into a conduit for a patient interface by retracting to a closed position. Example vapor barriers may include a resilient membrane, cover, bellows, flap, shutter or other suitable valve.

公开(公告)号：US09974909B2

公开(公告)日：2018-05-22

申请号：US14056828

申请日：2013-10-17

Applicant: MICRODOSE THERAPEUTX, INC.

Inventor： Henri M. Akouka ,  Daniel P. Becker

IPC: A61M15/00 ,  A61M16/00 ,  B65D83/06

CPC classification number: A61M15/0051 ,  A61M15/001 ,  A61M15/0021 ,  A61M15/0043 ,  A61M15/0045 ,  A61M15/005 ,  A61M15/0055 ,  A61M15/0065 ,  A61M15/0085 ,  A61M2016/0021 ,  A61M2202/0266 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/0294 ,  A61M2205/12 ,  A61M2205/8206 ,  A61M2250/00

Abstract: A method and device for delivering a pharmaceutical to the airway of a human or animal patient, in one aspect, includes a dose drum formed into a cylinder and including a plurality of dose compartments for containing individual doses. In another aspect, the device may include a reservoir containing a pharmaceutical material in bulk form and a metering recess for metering the pharmaceutical material to form a pharmaceutical dose. Another aspect provides an inhaler with a combined reservoir and dosing chamber configured to contain multiple doses of a pharmaceutical material.

公开(公告)号：US09895199B2

公开(公告)日：2018-02-20

申请号：US14301692

申请日：2014-06-11

Applicant: Mallinckrodt Hospital Products IP Limited

Inventor： Frederick J. Montgomery ,  Duncan P. Bathe ,  Daniel J. Lee ,  Scott I. Biba ,  Todd J. Bakken

IPC: A61M16/12 ,  A61M16/20 ,  A61B19/00 ,  A61M16/10 ,  A61M16/14 ,  A61B90/90 ,  A61B90/94 ,  A61B90/98

CPC classification number: A61M16/14 ,  A61B90/90 ,  A61B90/94 ,  A61B90/98 ,  A61M16/104 ,  A61M16/12 ,  A61M16/20 ,  A61M16/209 ,  A61M2202/0208 ,  A61M2202/0233 ,  A61M2202/0266 ,  A61M2202/0275 ,  A61M2205/6045 ,  A61M2205/6054

Abstract: A valve assembly comprising a housing and a valve, the valve being disposed within the housing, a first indexed member integral to the housing, the first indexed member adapted to be complementary to a second indexed member, and a radio frequency identification device adapted to communicate with a radio frequency receiver, the valve being configured to align with a canister, seal the canister and open in a single movement. A drug containment device having said valve assembly is also disclosed.

公开(公告)号：US20170312308A1

公开(公告)日：2017-11-02

申请号：US15653810

申请日：2017-07-19

Applicant: THE MCLEAN HOSPITAL CORPORATION

Inventor： Edward G. Meloni ,  Marc J. Kaufman

IPC: A61K33/00 ,  A61K9/00 ,  A61K33/36 ,  A61M16/12 ,  B82Y5/00 ,  A61M16/22 ,  A61M16/06 ,  A61F9/02 ,  A61M16/08 ,  A61M21/00

CPC classification number: A61K33/00 ,  A61F9/029 ,  A61K9/0048 ,  A61K33/36 ,  A61M16/06 ,  A61M16/0891 ,  A61M16/12 ,  A61M16/22 ,  A61M21/00 ,  A61M2202/0208 ,  A61M2202/0266 ,  A61M2202/0291 ,  A61M2205/502 ,  A61M2210/0612 ,  A61M2250/00 ,  B82Y5/00 ,  A61K2300/00 ,  A61M2202/0007

Abstract: The present invention relates generally to the fields of treating psychiatric disorders, in particular, anxiety disorders including post-traumatic stress disorder (PTSD) in subjects, e.g., human subjects, by administering a xenon and/or argon containing composition. Treatments can also employ psychotherapy in combination with administration of xenon and/or argon, alone or in combination with additional psychotherapeutic medications to treat the anxiety disorder and reduce a symptom of the anxiety disorder in the subject.

公开(公告)号：US09649465B2

公开(公告)日：2017-05-16

申请号：US12868368

申请日：2010-08-25

Applicant: William R. Wilkinson ,  Allan Sten Westersten ,  H. David Shockley, Jr.

Inventor： William R. Wilkinson ,  Allan Sten Westersten ,  H. David Shockley, Jr.

IPC: A61M16/10 ,  A62B7/10 ,  A61M16/20 ,  A61M16/06 ,  A61M16/00 ,  B01D53/04

CPC classification number: A61M16/101 ,  A61M16/0003 ,  A61M16/0051 ,  A61M16/0069 ,  A61M16/024 ,  A61M16/0666 ,  A61M16/0672 ,  A61M16/0677 ,  A61M16/10 ,  A61M16/1055 ,  A61M16/107 ,  A61M16/208 ,  A61M2016/0015 ,  A61M2016/0021 ,  A61M2016/0024 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2016/1025 ,  A61M2202/0208 ,  A61M2202/0266 ,  A61M2205/17 ,  A61M2205/18 ,  A61M2205/3327 ,  A61M2205/3372 ,  A61M2205/3375 ,  A61M2205/3553 ,  A61M2205/3592 ,  A61M2205/42 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/7518 ,  A61M2205/8206 ,  A61M2205/8237 ,  A61M2209/088 ,  B01D53/0446 ,  B01D53/0454 ,  B01D2253/108 ,  B01D2256/12 ,  B01D2259/402 ,  B01D2259/4533 ,  B01D2259/455 ,  G01N2291/02881

Abstract: An oxygen concentrator may rely on a pressure swing adsorption process to produce an oxygen enriched gas stream from canisters filled with granules capable of separation of oxygen from an air stream. The adsorption process uses a cyclical pressurization and venting of the canisters to generate an oxygen enriched gas stream. The oxygen concentrator system may operate in multiple modes, automatically determined or selected by the user, to take into account the different activity levels of the user.

公开(公告)号：US09586702B2

公开(公告)日：2017-03-07

申请号：US13306002

申请日：2011-11-29

Applicant: Brian W. Lariviere

Inventor： Brian W. Lariviere

IPC: A61M16/10 ,  B64G1/48 ,  C01B13/02 ,  C01B21/02 ,  B64G1/22

CPC classification number: B64G1/48 ,  A61M16/10 ,  A61M2202/0208 ,  A61M2202/0266 ,  A61M2202/0283 ,  B64G2001/224 ,  C01B13/0203 ,  C01B21/02

Abstract: A multi-function nitrous oxide system is disclosed for producing breathing air. The system includes a nitrous oxide storage container and a nitrous oxide conversion element connected with the nitrous oxide storage container. The nitrous oxide conversion element is downstream from the nitrous oxide storage container and produces hot fluid. The system includes a breathing air storage container connected with the nitrous oxide conversion element downstream from the nitrous oxide conversion element.

Abstract translation: 公开了一种用于产生呼吸空气的多功能氧化亚氮系统。 该系统包括与一氧化二氮储存容器连接的一氧化二氮储存容器和一氧化二氮转化元件。 一氧化二氮转化元件在一氧化二氮储存容器的下游，并产生热流体。 该系统包括与氧化亚氮转化元件下游的一氧化二氮转化元件连接的呼吸空气存储容器。

公开(公告)号：US09539406B2

公开(公告)日：2017-01-10

申请号：US14022319

申请日：2013-09-10

Applicant: General Electric Company

Inventor： Erkki Heinonen

IPC: A61M15/00 ,  A61M16/00 ,  A61M16/08 ,  A61M16/10 ,  A61M16/18 ,  A61M16/01 ,  A61M16/12 ,  A61M16/20 ,  A61M16/22

CPC classification number: A61M16/0816 ,  A61M16/01 ,  A61M16/0891 ,  A61M16/104 ,  A61M16/12 ,  A61M16/18 ,  A61M16/202 ,  A61M16/208 ,  A61M16/22 ,  A61M2202/0208 ,  A61M2202/0266 ,  A61M2202/0283

Abstract: An interface device for supplying a gas flow for breathing is disclosed herein. The device includes at least one socket for detachably connecting an apparatus for supplying anesthetic agent, at least one gas output opening for delivering the fresh gas to the apparatus, and at least one gas input opening for receiving the fresh gas mixed with anesthetic agent. The device also includes a connection valve and at least four ports in flow communication with the valve, a first port receiving the gas, a second port providing a communication with the output opening, a third port providing a communication with the input opening, and a fourth port providing a communication for breathing, the valve having a first operational state disconnecting communication between the first and second port, and to second operational state providing communication between the first and second port, but also between the third and fourth port.

Abstract translation: 本文公开了一种用于提供用于呼吸的气流的接口装置。 该装置包括至少一个用于可拆卸地连接用于供应麻醉剂的装置的插座，用于将新鲜气体输送到装置的至少一个气体输出开口，以及用于接收与麻醉剂混合的新鲜气体的至少一个气体输入口。 该装置还包括连接阀和至少四个与阀流动连通的端口，接收气体的第一端口，提供与输出开口的连通的第二端口，提供与输入开口的连通的第三端口，以及 第四端口提供用于呼吸的通信，所述阀具有断开第一和第二端口之间的通信的第一操作状态以及提供第一和第二端口之间以及第三端口与第四端口之间的通信的第二操作状态。

公开(公告)号：US09526744B2

公开(公告)日：2016-12-27

申请号：US14302282

申请日：2014-06-11

Applicant: Air Liquide Santé (International)

Inventor： Pierre De Villemeur ,  Laurent Lecourt

IPC: A61K33/00 ,  C01B21/24 ,  C01B21/04 ,  A61M16/12

CPC classification number: A61K33/00 ,  A61M16/107 ,  A61M16/12 ,  A61M2202/0266 ,  A61M2202/0275 ,  A61M2202/0283 ,  A61M2207/00 ,  C01B21/0422 ,  C01B21/0433 ,  C01B21/045 ,  C01B21/24 ,  C01B2210/0006 ,  C01B2210/001 ,  C01B2210/0045 ,  C01B2210/0062

Abstract: The invention relates to a method for producing an NO/N2 gaseous mixture, comprising the steps of effecting a purification of impure gaseous nitrogen containing impurities at least of the O2 type by putting the impure nitrogen in contact with a catalyst and then with a molecular sieve; mixing the pure nitrogen obtained with nitric oxide (NO), and obtaining a mixture formed from NO and pure nitrogen containing an NO content of less than 20% by volume and a proportion of impurities of the O2 type of less than 5 ppmv and of the H2O type of less than 40 ppmv. The NO/nitrogen mixture may undergo supplementary dilutions with pure nitrogen. Such NO/nitrogen mixtures can be used for treating, by inhalation, pulmonary vasoconstrictions in adults or children, in particular in new-born babies suffering from primitive pulmonary hypertension or in patients undergoing heart surgery.

Abstract translation: 本发明涉及一种生产NO / N2气体混合物的方法，包括以下步骤：通过将不纯氮与催化剂接触，然后用分子筛来净化至少含有O 2型杂质的不纯气态氮 ; 将得到的纯氮与一氧化氮（NO）混合，得到由NO和NO含量低于20体积％，O 2类型的杂质的比例小于5ppmv的纯氮和 H2O类型小于40 ppmv。 NO /氮混合物可以用纯氮进行补充稀释。 这种NO /氮混合物可用于通过吸入治疗成人或儿童的肺血管收缩，特别是在患有原始肺动脉高压的新生婴儿或患有心脏手术的患者中。

公开(公告)号：US09480830B1

公开(公告)日：2016-11-01

申请号：US14254003

申请日：2014-04-16

Applicant: Jose Azocar

Inventor： Jose Azocar

IPC: A61M37/00 ,  A61M1/00 ,  A61F13/00 ,  A61M27/00 ,  A61M5/00 ,  A61M35/00

CPC classification number: A61M37/00 ,  A61F13/00068 ,  A61F2013/00089 ,  A61F2013/0017 ,  A61M1/0025 ,  A61M1/0058 ,  A61M1/0062 ,  A61M1/0084 ,  A61M1/0088 ,  A61M1/009 ,  A61M27/00 ,  A61M35/00 ,  A61M2005/006 ,  A61M2037/0007 ,  A61M2202/0208 ,  A61M2202/025 ,  A61M2202/0266

Abstract: An assembly used to promote wound healing through the creation of an oxygen gradient, whereby the oxygen gradient hastens the diffusion of oxygen from underlying capillaries and subcutaneous tissue up through and over an overlying target site of skin tissue. In an exemplary embodiment, the assembly provides a flush cycle and/or a negative pressure cycle to enhance the flow of oxygen from the subcutaneous tissue and the capillaries to the target site. In an exemplary embodiment, the assembly further comprises a means for maintaining a constant relative humidity over the wound site.

Abstract translation: 用于通过产生氧气梯度促进伤口愈合的组件，由此氧气梯度加速氧气从下面的毛细血管和皮下组织扩散通过并超过皮肤组织的上覆目标部位。 在示例性实施例中，组件提供冲洗循环和/或负压循环以增强从皮下组织和毛细血管到目标部位的氧气流。 在示例性实施例中，组件还包括用于在伤口部位上保持恒定的相对湿度的装置。

公开(公告)号：US09295802B2

公开(公告)日：2016-03-29

申请号：US14629742

申请日：2015-02-24

Applicant: INO Therapeutics LLC

Inventor： Duncan P. Bathe ,  John Klaus ,  David Christensen

IPC: A62B9/02 ,  F16K31/02 ,  A61M16/10 ,  A61M16/20 ,  A61M16/00 ,  A61M16/12 ,  A61M16/08 ,  A61M16/16

CPC classification number: A61M16/202 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/04 ,  A61M16/0666 ,  A61M16/0808 ,  A61M16/0833 ,  A61M16/085 ,  A61M16/0875 ,  A61M16/1005 ,  A61M16/104 ,  A61M16/12 ,  A61M16/16 ,  A61M16/20 ,  A61M16/204 ,  A61M16/208 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2016/102 ,  A61M2016/1025 ,  A61M2016/1035 ,  A61M2202/0208 ,  A61M2202/0233 ,  A61M2202/0266 ,  A61M2202/0275 ,  A61M2202/0283 ,  A61M2205/18 ,  A61M2205/27 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/35 ,  A61M2205/3561 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/6009 ,  A61M2205/6072 ,  A61M2205/8206 ,  A61M2209/084 ,  F17C2205/013 ,  F17C2205/0161 ,  F17C2205/0308 ,  F17C2205/05 ,  F17C2205/054 ,  F17C2221/01 ,  F17C2221/011 ,  F17C2250/032 ,  F17C2270/02

Abstract: A gas delivery system including a gas delivery device, a control module and a gas delivery mechanism is described. An exemplary gas delivery device includes a valve assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line-of-sight signals to communicate the gas data to a control module. Exemplary gas delivery mechanisms include a ventilator and a breathing circuit. Methods of administering gas are also described.

Abstract translation: 描述了包括气体输送装置，控制模块和气体输送机构的气体输送系统。 示例性气体输送装置包括具有阀的阀组件和包括与存储器通信的存储器，处理器和收发器的电路。 存储器可以包括气体数据，例如气体识别，气体呼出和气体浓度。 阀组件电路上的收发器可以发送无线光学视线信号，以将气体数据传送到控制模块。 示例性气体输送机构包括呼吸机和呼吸回路。 还描述了给予气体的方法。