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公开(公告)号:US20220298265A1
公开(公告)日:2022-09-22
申请号:US17836338
申请日:2022-06-09
发明人: Kevin J. Edgar , Brittany L.B. Nichols , Junyi Chen , Charles Frazier , Lynne S. Taylor , Laura I. Mosquera-Giraldo , Ann Norris , Benjamin Adams
IPC分类号: C08B37/08 , C08B37/02 , C08B31/18 , C08B31/12 , C08B11/04 , C08J3/24 , C08B33/04 , C08B11/20
摘要: A method for the synthesis of alkyl ω-carboxy(hydroxyethyl) polysaccharides is described. The method includes methylating or ethylating a polysaccharide or providing a methylated or ethylated polysaccharide, hydroxyethylating the methylated or ethylated polysaccharide, and oxidizing the hydroxyethylated polysaccharide to form the ω-carboxy(hydroxyethyl) polysaccharide. A method for the synthesis of oxidized polysaccharides is also described. The method includes hydroxypropylating a polysaccharide and oxidizing the hydroxypropylated polysaccharides. A method for the production of a solid capable of forming a hydrogel is also described. The method includes combining a first solution comprising an oxidized oligo(hydroxypropyl) polysaccharide bearing one or more ketone groups with a second solution comprising an amine substituted polysaccharide to form a third solution, and removing solvent from the third solution to form the solid, or adding an additional solvent to the third solution to precipitate the solid. Novel polysaccharides and hydrogels prepared according to these methods are also described.
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公开(公告)号:US20210155718A1
公开(公告)日:2021-05-27
申请号:US16632794
申请日:2018-07-25
发明人: Giovanna Canalli Ortiz Moreira , Thais Bezerra Claudio de Avila , Pamela Araujo Rodrigues Muchiutti , Cinthia Fernanda de Souza Ferreira Garcia
IPC分类号: C08B31/18 , A61K8/9789 , A61Q19/00
摘要: The present invention relates to a novel process for bleaching babassu, preferably from the species Orbignya phalerata. In the process of the present invention, the temperature is controlled and a defoamer is added, and also only water is used for extraction, thereby allowing a more efficient and economical process.
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公开(公告)号:US20200270370A1
公开(公告)日:2020-08-27
申请号:US16637648
申请日:2018-07-11
发明人: Mikael Brynolf , Åke Ståhl , Mathias Samuelsson
IPC分类号: C08B31/18 , A23L5/20 , A23L29/219 , A23L3/3508 , A23L3/3544
摘要: A method for preparing an inhibited starch, wherein it comprises the steps of a) providing a slurry containing a native granular starch obtained from a starch containing raw material, b) alkalizing the slurry by adding ammonia or by adding one or more compounds having the ability to release or produce ammonia in the slurry, c) adjusting the pH of the slurry to a value between 7 and 10, d) adding at least one oxidant being a source of active chlorine to the slurry for a reaction with said ammonia, e) adding at least one organic acid or a bisulfite to the slurry with a view to eliminating any residual oxidant, off-taste, and undesired smell, and f) adding at least one antioxidant to the slurry with a view to stabilizing the achieved inhibition of the starch during prolonged warehouse storage, is disclosed, as well as a starch having increased viscosity when cooked in hard water compared to when cooked in distilled water; an inhibited starch prepared with the method according to the present invention; use of said inhibited starch in a food product; and a food product containing said inhibited starch.
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54.
公开(公告)号:US20190276563A1
公开(公告)日:2019-09-12
申请号:US16389234
申请日:2019-04-19
发明人: Peter GEISSER , Erik Philipp , Walter Richle
IPC分类号: C08B30/18 , A61K47/61 , C08B31/18 , C08B37/00 , A61K31/295 , A61K45/06 , A61K33/26 , A61K31/718
摘要: A water soluble iron carbohydrate complex obtainable from an aqueous solution of iron(III) salt and an aqueous solution of the oxidation product of one or more maltrodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, a process for its production and a medicament for the treatment and prophylaxis of iron deficiency conditions.
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公开(公告)号:US10195312B2
公开(公告)日:2019-02-05
申请号:US15427801
申请日:2017-02-08
申请人: Xin Ji
发明人: Xin Ji , Cheng Xing , Xueshen Shi
IPC分类号: A61K31/718 , A61L31/04 , C08B31/08 , C08B31/02 , C08B33/04 , C08B31/10 , C08B31/16 , C08B35/02 , C08B33/06 , C08B35/06 , C08B35/04 , C08B33/02 , C08B31/12 , C08B31/04 , C08B30/20 , C08B31/00 , C08B31/18 , C08B30/00 , A61K31/738 , A61L24/08 , A61L26/00 , A61K45/06 , A61K9/14 , C08L3/04 , C08L3/18 , C08L89/06 , A61K9/00 , A61K9/19 , A61L24/00 , A61L24/10 , A61L31/12
摘要: A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
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公开(公告)号:US20180112012A1
公开(公告)日:2018-04-26
申请号:US15562490
申请日:2016-03-11
发明人: Massimo Vezzani
CPC分类号: C08B31/18 , B01J19/1812 , B01J2204/005 , B01J2208/00752 , B01J2208/065 , B01J2219/00033 , B01J2219/00085 , C01B15/01
摘要: A process for the oxidation of powder materials containing starch, which comprises the successive steps of mixing a powder material comprising starch with an aqueous solution of hydrogen peroxide (H2O2) and adding to the mixture thus obtained an aqueous solution of ammonia and reacting it with said mixture; the process may also comprise a further step of drying the aforementioned mixture to obtain a powder material containing oxidized starch; the process may advantageously comprise the steps of:—feeding a continuous flow of powder material containing starch into a first reactor (R) comprising a cylindrical tubular body (1) and a rotor, arranged in the cylindrical tubular body, comprising a shaft (8) provided with elements (9) projecting radially therefrom and rotated at a speed greater than or equal to 50 rpm,—feeding into said reactor also a continuous flow of an aqueous solution of hydrogen peroxide—reacting the powder material containing starch and the hydrogen peroxide;—discharging from a discharge opening (7) of the first reactor a continuous flow of a wet powder and feeding this continuous flow into a second reactor (R′) comprising a cylindrical tubular body (101) and a rotor, arranged in the cylindrical tubular body, comprising a shaft (108) provided with elements (109) projecting radially therefrom and rotated at a speed greater than or equal to 50 rpm;—feeding into the second reactor (R′) also a continuous flow of an aqueous solution of ammonia,—discharging from a discharge opening (107) of the second reactor a continuous flow of a wet powder comprising oxidized starch;—drying the wet powder to a moisture content less than or equal to 20% by weight, thereby obtaining a powder material containing oxidized starch.
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公开(公告)号:US20180105609A1
公开(公告)日:2018-04-19
申请号:US15559976
申请日:2015-05-06
发明人: Udaya Bhaskara Rao Siripalli , Lakshmi Narasimhulu Gorentla , Veera Reddy Arava , Mohana Rao Manam , Venkateswarlu Jasti
摘要: The present invention provides an improved process for the preparation of Ferric carboxymaltose (FCM) complex. In this process the oxidation of maltodextrins are carried out by using an organic hypo halite in the presence of a catalyst and a phase transfer catalyst and later complex formation with ferric salt or ferric hydroxide or iron hydroxide maltodextrin complex.
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公开(公告)号:US09605087B1
公开(公告)日:2017-03-28
申请号:US14753806
申请日:2015-06-29
申请人: General Mills, Inc.
发明人: Ling-Hua Han , Ya-Jane Wang
IPC分类号: C08B31/00 , C08B31/08 , C08B31/12 , A61K31/718 , C08B31/18
CPC分类号: C08B31/18 , A23L29/219 , C08B31/12
摘要: A process for modifying starch is described. The process can be used as an alternative to conventional starch modification processes, such as substitution and crosslinking. The process and resulting product can reduce, substantially reduce, substantially eliminate or eliminate the sodium level typically associated with conventionally modified starch products.
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公开(公告)号:US09283246B2
公开(公告)日:2016-03-15
申请号:US13606403
申请日:2012-09-07
申请人: Dominik Fenn , Thomas Schweitzer
发明人: Dominik Fenn , Thomas Schweitzer
IPC分类号: A61K31/718 , A61K31/724 , C08B31/18
CPC分类号: A61K31/724 , A61K31/718
摘要: The present invention relates to pharmaceutical compositions containing carboxylated starch derivatives as well a their use as osmotics in particular for use in the treatment of chronic renal failure by dialysis.
摘要翻译: 本发明涉及包含羧化淀粉衍生物的药物组合物以及它们作为渗透剂的用途,特别是用于通过透析治疗慢性肾功能衰竭。
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60.
公开(公告)号:US20150148531A1
公开(公告)日:2015-05-28
申请号:US14401673
申请日:2013-05-15
CPC分类号: C08B31/18 , C08B15/04 , D21H17/24 , D21H17/28 , Y02P20/582
摘要: The invention relates to a method for the manufacture of carbonyl derivatives of polysaccharides and to the oxidization of polysaccharides in the presence of nitrogen dioxide to yield carbonyl derivatives of polysaccharides. The products including carbonyl derivatives of polysaccharides, obtained by the method are also described.
摘要翻译: 本发明涉及制备多糖的羰基衍生物的方法和在二氧化氮存在下氧化多糖以产生多糖的羰基衍生物。 还描述了通过该方法获得的包括多糖的羰基衍生物的产物。
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