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    IMAGE PICKUP DEVICE
    51.
    发明申请
    IMAGE PICKUP DEVICE 审中-公开
    图像拾取器件

    公开(公告)号：US20110249155A1

    公开(公告)日：2011-10-13

    申请号：US13084068

    申请日：2011-04-11

    申请人： Shuzo Hiraide

    发明人： Shuzo Hiraide

    IPC分类号： H04N9/64

    CPC分类号： H04N5/3692 ,  G02B21/0004 ,  G02B21/26 ,  G02B21/34 ,  G02B21/365 ,  H04N9/045

    摘要： An image pickup device may include a stage moving a sample, a line sensor that comprises an imaging element including pixels arranged in a line shape, the line sensor scanning and acquiring an image of the sample, a spectrum detection unit that comprises a first light receiving element including a first color filter and a second light receiving element including a second color filter, the first color filter and the second color filter having different spectral transmittance distributions, the first light receiving element and the second light receiving element scanning a first portion of the sample so as to acquire spectrum information of the first portion, an optical system that introduces a light from the sample to the line sensor and the spectrum detection unit, and a correction device that corrects the image, which has been acquired by the line sensor, based on the spectrum information of the first portion.

    摘要翻译： 图像拾取装置可以包括移动样本的台，线传感器，其包括成像元件，所述成像元件包括以线状排列的像素，所述线传感器扫描并获取样本图像;频谱检测单元，包括第一光接收 包括第一滤色器的元件和包括第二滤色器的第二光接收元件，所述第一滤色器和所述第二滤色器具有不同的光谱透射率分布，所述第一光接收元件和所述第二光接收元件扫描所述第一滤色器的第一部分 采样，以获取第一部分的光谱信息，将来自样品的光引入线传感器和光谱检测单元的光学系统，以及校正由线传感器获取的图像的校正装置， 基于第一部分的频谱信息。

    Interferometer utilizing polarization scanning
    52.
    发明授权
    Interferometer utilizing polarization scanning 有权
    干涉仪利用偏振扫描

    公开(公告)号：US07978337B2

    公开(公告)日：2011-07-12

    申请号：US12267077

    申请日：2008-11-07

    申请人： Peter De Groot ,  Xavier Colonna De Lega

    发明人： Peter De Groot ,  Xavier Colonna De Lega

    IPC分类号： G01B9/02 ,  G02B21/00

    CPC分类号： G02B21/0004

    摘要： In one aspect, the disclosure features methods that include using a microscope to direct light to a test object and to direct the light reflected from the test object to a detector, where the light includes components having orthogonal polarization states, varying an optical path length difference (OPD) between the components of the light, acquiring an interference signal from the detector while varying the OPD between the components, and determining information about the test object based on the acquired interference signal.

    摘要翻译： 在一个方面，本发明的特征在于包括使用显微镜将光引导到测试对象并将从测试对象反射的光引导到检测器的方法，其中光包括具有正交偏振态的分量，改变光路长度差 （OPD），在改变组件之间的OPD的同时获取来自检测器的干扰信号，并且基于所获取的干扰信号确定关于测试对象的信息。

    ACOUSTIC ASSISTED PHASE CONJUGATE OPTICAL TOMOGRAPHY
    54.
    发明申请
    ACOUSTIC ASSISTED PHASE CONJUGATE OPTICAL TOMOGRAPHY 有权
    声学辅助相结合光学平片图

    公开(公告)号：US20110108707A1

    公开(公告)日：2011-05-12

    申请号：US12943841

    申请日：2010-11-10

    申请人： Meng Cui ,  Ying Min Wang ,  Charles DiMarzio ,  Changhuei Yang

    发明人： Meng Cui ,  Ying Min Wang ,  Charles DiMarzio ,  Changhuei Yang

    IPC分类号： H01L27/00 ,  G01N21/64

    CPC分类号： G02B21/0056 ,  A61B5/0059 ,  A61B5/0066 ,  G01N21/1717 ,  G01N21/4795 ,  G01N21/6456 ,  G01N2021/1708 ,  G01N2021/1727 ,  G02B21/00 ,  G02B21/0004 ,  G02B21/0068 ,  G02B21/0092 ,  Y10T29/49826

    摘要： A light microscope for imaging a sample containing one or more fluorescent agents, comprising a source for generating acoustic waves that are focused at a focus in the sample, wherein the acoustic waves frequency shift a frequency of light passing through the focus, thereby creating a frequency shifted light beam; at least one spatial light modulator (SLM) positioned to illuminate the sample with an output beam that is an optical phase conjugate of the frequency shifted light beam, wherein the output beam is a reflection of a first reference beam off one or more pixels of the SLM, and the pixels are for modulating the first reference beam to create the output beam; and a detector positioned to detect fluorescence generated by the output beam exciting the fluorescent agents at the focus in the sample, thereby imaging the sample.

    摘要翻译： 一种用于对含有一种或多种荧光剂的样品进行成像的光学显微镜，其包括用于产生聚焦在样品中的聚焦的声波的源，其中所述声波使通过所述焦点的光的频率偏移，由此产生频率 移动光束; 至少一个空间光调制器（SLM），定位成用作为所述频移光束的光学相位共轭的输出光束照射所述样本，其中所述输出光束是第一参考光束的反射离开所述第一参考光束的一个或多个像素 SLM，并且像素用于调制第一参考光束以产生输出光束; 以及检测器，用于检测在样品中焦点处激发荧光剂的输出光束产生的荧光，从而对样品进行成像。

    MODULATION CONTRAST MICROSCOPE
    57.
    发明申请
    MODULATION CONTRAST MICROSCOPE 有权
    调制对比显微镜

    公开(公告)号：US20100284067A1

    公开(公告)日：2010-11-11

    申请号：US12743751

    申请日：2008-11-18

    申请人： Kumiko Matsui

    发明人： Kumiko Matsui

    IPC分类号： G02B21/08

    CPC分类号： G02B21/086 ,  G02B21/0004 ,  G02B21/14 ,  G02B27/46

    摘要： A modulation contrast microscope that affords good view of sperm in ICSI, in particular, good view during sperm manipulation in ICSI, by improving contrast of the end portion of the tail includes the modulation contrast microscope comprises an aperture member having a partial aperture disposed at or near the front focal plane of a condenser lens, and a modulator disposed at a plane substantially conjugate with the aperture member, at or near the rear focal plane of a first objective lens or a conjugate plane thereof. The transmittance T(%) of a region of the modulator, corresponding to the partial aperture, satisfies the condition 1 £ T £ 8. Good viewing for ICSI sperm manipulation can be obtained as a result.

    摘要翻译： 调制对比显微镜在ICSI中提供精子的良好视野，特别是在ICSI精子操纵期间的良好视野，通过改善尾部末端部分的对比度，包括调制对比显微镜，包括具有设置在或 靠近聚光透镜的前焦平面，以及调制器，设置在与第一物镜或其共轭平面的后焦平面处或附近的基本上与孔构件共轭的平面处。 对应于部分孔径的调制器的区域的透射率T（％）满足条件1£T£8.因此，可以获得良好的ICSI精子操作观察结果。

    BEAM DEVICE SYSTEM COMPRISING A PARTICLE BEAM DEVICE AND AN OPTICAL MICROSCOPE
    58.
    发明申请
    BEAM DEVICE SYSTEM COMPRISING A PARTICLE BEAM DEVICE AND AN OPTICAL MICROSCOPE 有权
    包含粒子束装置和光学显微镜的束装置系统

    公开(公告)号：US20100224780A1

    公开(公告)日：2010-09-09

    申请号：US12734613

    申请日：2008-11-11

    申请人： Bernd Spruck ,  Martin Edelmann ,  John Craven ,  Robert Taylor ,  Martin Kuhner

    发明人： Bernd Spruck ,  Martin Edelmann ,  John Craven ,  Robert Taylor ,  Martin Kuhner

    IPC分类号： G01N23/00 ,  G21K5/08

    CPC分类号： H01J37/20 ,  G02B21/0004 ,  H01J37/18 ,  H01J37/228 ,  H01J37/26 ,  H01J2237/2003 ,  H01J2237/2006 ,  H01J2237/204 ,  H01J2237/2608

    摘要： A beam device, in particular a particle beam device, for analyzing an object is provided, as well as a system comprising a particle beam device and an optical microscope for optically analyzing an object. The beam device simplifies the exchange and reduces the time of the exchange of objects to be examined. The beam device includes at least one beam generator that generates a beam, at least one objective lens that focuses the beam on an object arranged in a holding element. The objective lens comprises at least one connecting element. The holding element may be connected to the connecting element so that the holding element is removable from the connecting element for modification of the object. Alternatively, the holding element may be mounted to a beam column.

    摘要翻译： 提供了用于分析物体的光束装置，特别是粒子束装置，以及包括用于光学分析物体的粒子束装置和光学显微镜的系统。 光束装置简化了交换并减少了被检查物体交换的时间。 光束装置包括产生光束的至少一个光束发生器，将光束聚焦在布置在保持元件中的物体上的至少一个物镜。 物镜包括至少一个连接元件。 保持元件可以连接到连接元件，使得保持元件可从连接元件移除以便对象的修改。 或者，保持元件可以安装到梁柱。

    Microscope having a surgical slit lamp having a laser light source
    59.
    发明授权
    Microscope having a surgical slit lamp having a laser light source 有权
    具有手术切口灯的显微镜具有激光光源

    公开(公告)号：US07724429B2

    公开(公告)日：2010-05-25

    申请号：US11459344

    申请日：2006-07-22

    申请人： Ulrich Sander

    发明人： Ulrich Sander

    IPC分类号： G02B21/06

    CPC分类号： A61B3/135 ,  A61B90/20 ,  G02B21/0004 ,  G02B21/06

    摘要： The invention relates to a microscope (10) having an illumination apparatus (26) having a light source (1) and an optical system. The light source (1) is embodied to output a coherent light beam bundle along a defined illumination beam path (2a), and the optical system in the illumination beam path (2a) encompasses a spatial light modulator (3) for modifying the illuminated field (4). A surgical microscope (10) is preferably equipped with an illumination apparatus (26) of this kind that is arranged adjustably in two directions on the surgical microscope (10).

    摘要翻译： 本发明涉及具有具有光源（1）和光学系统的照明装置（26）的显微镜（10）。 光源（1）被实现为沿着限定的照明光束路径（2a）输出相干光束，并且照明光束路径（2a）中的光学系统包含用于修改照明场的空间光调制器（3） （4）。 手术显微镜（10）优选配备有这样的照明装置（26），其在外科手术显微镜（10）上在两个方向上可调节地布置。

    SOLID-STATE MICROSCOPE
    60.
    发明申请
    SOLID-STATE MICROSCOPE 有权
    固态显微镜

    公开(公告)号：US20100033561A1

    公开(公告)日：2010-02-11

    申请号：US12103920

    申请日：2008-04-16

    申请人： Stephen D. Hersee

    发明人： Stephen D. Hersee

    IPC分类号： H04N7/18 ,  H01L33/00 ,  H01L21/28

    CPC分类号： G02B21/0004 ,  B82Y15/00 ,  B82Y20/00 ,  G02B21/00 ,  G02B21/002 ,  G02B21/06 ,  G02B21/36 ,  G02B21/361 ,  H01L27/156 ,  H01L33/0025 ,  H01L33/0075 ,  H01L33/06 ,  H01L33/18 ,  H01L33/24 ,  H01L33/32 ,  H01L33/36 ,  H01L2933/0016

    摘要： Exemplary embodiments provide solid-state microscope (SSM) devices and methods for processing and using the SSM devices. The solid-state microscope devices can include a light emitter array having a plurality of light emitters with each light emitter individually addressable. During operation, each light emitter can be biased in one of three operating states including an emit state, a detect state, and an off state. The light emitter can include an LED (light emitting diode) including, but not limited to, a nanowire based LED or a planar LED to provide various desired image resolutions for the SSM devices. In an exemplary embodiment, for near-field microscopy, the resolution of the SSM microscope can be essentially defined by the pitch p, i.e., center-to-center spacing between two adjacent light emitters, of the light emitter array.

    摘要翻译： 示例性实施例提供了用于处理和使用SSM装置的固态显微镜（SSM）装置和方法。 固态显微镜装置可以包括具有多个发光体的光发射器阵列，每个发光体可单独寻址。 在操作期间，每个光发射器可以被偏置在包括发射状态，检测状态和关闭状态的三种操作状态之一中。 光发射器可以包括LED（发光二极管），其包括但不限于基于纳米线的LED或平面LED，以为SSM器件提供各种期望的图像分辨率。 在一个示例性实施例中，对于近场显微镜，SSM显微镜的分辨率可以基本上由光发射器阵列的间距p，即两个相邻发光体之间的中心到中心间隔定义。