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公开(公告)号:US20240331890A1
公开(公告)日:2024-10-03
申请号:US18738493
申请日:2024-06-10
申请人: Curium US LLC
发明人: Maxim Kiselev
CPC分类号: G21K1/02 , G21G1/10 , G21K5/08 , H05H6/00 , H05H13/005
摘要: A target carrier assembly includes a housing, a target, and a collimator. The housing includes a collimator compartment and a target compartment divided by a vacuum window foil, the collimator being removably disposed within the collimator compartment, and the target being disposed within the target compartment. The collimator compartment is attached to a cyclotron beam line in the irradiation position, and the target compartment is in fluid communication with a cooling fluid supply line and a cooling fluid return line in the irradiation position. The target is cooled by the cooling fluid from the cooling fluid supply line. The collimator directs a particle beam from the cyclotron beam line to irradiate the target and includes a beam entry diameter and a beam exit diameter. The collimator is in thermal contact with the collimator compartment.
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公开(公告)号:US12062463B2
公开(公告)日:2024-08-13
申请号:US17302412
申请日:2021-05-03
CPC分类号: G21G4/02 , G21G1/10 , G21K5/08 , G21K5/10 , H05H3/06 , H05H6/00 , A61N5/10 , A61N5/1077 , A61N2005/1087 , A61N2005/109
摘要: Apparatuses and methods for producing neutrons for applications such as boron neutron capture therapy (BNCT) are described. An apparatus can include a rotary fixture with a coolant inlet and a coolant outlet, and a plurality of neutron-producing segments. Each neutron-producing segment of the plurality of neutron-producing segments is removably coupled to the rotary fixture, and includes a substrate having a coolant channel circuit defined therein and a solid neutron source layer disposed thereon. The coolant channel circuits are in fluid communication with the coolant inlet and the coolant outlet.
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公开(公告)号:US12051518B2
公开(公告)日:2024-07-30
申请号:US18094127
申请日:2023-01-06
摘要: A target well of a target delivery assembly for use in an irradiation system operative to allow irradiation of a radioisotope target via a vessel penetration of a fission reactor. The target well includes an outer tube and an inner tube disposed therein so that an annulus is formed therebetween. The target is positioned in the inner tube during irradiation. At least one flow channel extends between a bottom end of the outer tube and a bottom end of the inner tube. An elevation piston is slidably disposed within the inner tube to elevate the target, the elevation piston including a one-way check valve allowing flow in a downward direction and preventing flow in an upward direction.
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公开(公告)号:US12014838B2
公开(公告)日:2024-06-18
申请号:US16113817
申请日:2018-08-27
发明人: David A. Rotsch , Nicholas A. Smith , David A. Ehst , Sergey A. Chemerisov , Jerry A. Nolen, Jr. , Michael Alexander Brown , James J. Grudzinski , James L. Bailey , Ronald T. Kmak
摘要: A system for producing and harvesting radioisotopes is provided, the system having a converter housing defining a first beam window; a converter carrier and cartridge in slidable communication with the converter housing; a target housing positioned downstream from the converter housing, the target housing defining a second beam window; and a target carrier in slidable communication with the target housing.
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公开(公告)号:US11832374B1
公开(公告)日:2023-11-28
申请号:US17060213
申请日:2020-10-01
CPC分类号: H05H6/00 , G21G1/001 , G21G1/0005 , G21G1/02 , G21G2001/0094 , G21K5/08
摘要: An annular radioisotope target and method therefor that includes an inner cladding tube and a helical coil-shaped foil ribbon disposed over the inner cladding tube. The helical coil-shaped foil ribbon has a first end, a second end, a first edge and a second edge. An outer cladding tube is disposed over the helical coil-shaped foil ribbon and inner cladding tube, and end caps are attached to the outer cladding tube and the inner cladding tube.
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公开(公告)号:US11800630B2
公开(公告)日:2023-10-24
申请号:US17277629
申请日:2019-03-12
发明人: Pietro Agostini
CPC分类号: H05H3/06 , H05H6/00 , G21G4/02 , G21K5/08 , H05H2242/10
摘要: An apparatus for generating neutrons may include: a hollow casing configured to rotate about a central axis, the casing including a wall having a central region substantially at the central axis and a peripheral region, wherein the wall defines a cavity, and wherein the cavity is configured to contain a first coolant fluid; an active layer at least partially on the peripheral region external to the cavity, wherein the active layer is configured to realize a neutron-generating reaction; at least one particle accelerator configured to direct an ion beam on the active layer to activate the neutron-generating reaction; movement means configured to rotate the casing about the central axis and to force the first coolant fluid to contact the wall at the active layer for cooling the casing; and external cooling including a second coolant fluid contacting at least an external portion of the wall.
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公开(公告)号:US11661668B2
公开(公告)日:2023-05-30
申请号:US17345719
申请日:2021-06-11
申请人: TRIUMF INC.
发明人: Paul Schaffer , Francois Benard , Kenneth R. Buckley , Victoire Hanemaayer , Cornelia Manuela Hoehr , Julius Alexander Klug , Michael S. Kovacs , Thomas J. Morley , Thomas J. Ruth , John Valliant , Stefan K. Zeisler , Maurice G. Dodd
IPC分类号: G21G1/00 , C25D13/02 , C25D13/22 , G21F5/14 , G21K5/08 , B22F1/145 , H05H6/00 , B22F7/02 , G21G1/10 , B22F3/10
CPC分类号: G21G1/001 , B22F1/145 , C25D13/02 , C25D13/22 , G21F5/14 , G21K5/08 , B22F3/10 , B22F7/02 , B22F2998/10 , B22F2999/00 , G21G1/10 , G21G2001/0042 , H05H6/00 , B22F2999/00 , B22F1/145 , B22F9/22 , B22F2999/00 , B22F9/22 , B22F2201/013 , B22F2998/10 , B22F1/145 , B22F3/10
摘要: A system for producing technetium-99m from molybdate-100. The system comprises: a target capsule apparatus for housing a Mo-100-coated target plate; a target capsule pickup apparatus for engaging, and delivering the target cell apparatus into a target station apparatus; target station apparatus for receiving and mounting therein the target capsule apparatus. The target station apparatus is engaged with a cyclotron for irradiating the Mo-100-coated target plate with protons. The irradiated target capsule apparatus is transferred to a receiving cell apparatus comprising a dissolution/purification module for receiving therein a proton-irradiated Mo-100-coated target plate. A conveyance conduit infrastructure interconnects: (i) the target capsule pickup apparatus with the target station apparatus, (ii) the target station apparatus and the receiving cell apparatus; and (iii) the receiving cell apparatus and the dissolution/purification module.
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公开(公告)号:US11551821B2
公开(公告)日:2023-01-10
申请号:US16548952
申请日:2019-08-23
摘要: A target irradiation system for irradiating a radioisotope target in a vessel penetration of a fission reactor, includes a target delivery assembly with a body defining a central bore, a basket that is slidably receivable within the central bore of the body, and a winch that is connected to the basket by a cable. The target delivery assembly is affixed to the vessel penetration of the reactor; and a target passage is in fluid communication with the target delivery assembly. The basket is configured to receive a radioisotope target therein via the target passage and be lowered into the vessel penetration of the reactor when irradiating the radioisotope target. The target delivery system forms a portion of the pressure boundary of the reactor when in fluid communication with the reactor.
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公开(公告)号:US11495365B1
公开(公告)日:2022-11-08
申请号:US16352516
申请日:2019-03-13
申请人: Gregory Gaehle
发明人: Gregory Gaehle
摘要: Among the various aspects of the present disclosure is the provision of systems for producing radioisotopes and improving the specific activity of radioisotopes (e.g., Cu-64 chloride). As described herein, the system includes a target material area or target material shape that matches the proton beam strike area or proton beam strike shape, resulting in optimal thickness with less target material required.
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公开(公告)号:US20220331608A1
公开(公告)日:2022-10-20
申请号:US17724027
申请日:2022-04-19
申请人: Aktina Corp.
摘要: Systems and methods for determining a radiation isocenter of a linear accelerator (LINAC). Determining the radiation isocenter may include determining a set of three-dimensional (3D) radiation beam axes of the LINAC from two-dimensional (2D) radiation transmission images. The radiation isocenter may be determined based on at least the set of 3D radiation beam axes. Determining the set of 3D radiation beam axes may including constructing a 3D radiation beam axis based on a determined location of a beam axis of a radiation beam generated with a gantry of the LINAC at an angle relative to a reference gantry angle, a determined center of a shadow of a radiation opaque marker in the radiation field of the radiation beam, and the gantry angle.
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