公开(公告)号：US12013929B2

公开(公告)日：2024-06-18

申请号：US18158621

申请日：2023-01-24

Applicant: Open Text Inc.

Inventor： Andrew Sandoval

IPC: G06F21/52 ,  B01D15/18 ,  G01N30/20 ,  G01N30/22 ,  G01N30/46 ,  G01N30/60 ,  G06F11/36

CPC classification number: G06F21/52 ,  B01D15/1885 ,  G01N30/20 ,  G01N30/22 ,  G01N30/466 ,  G01N30/6043 ,  G06F11/3688 ,  G01N2030/202 ,  G01N2030/207 ,  G06F2221/033

Abstract: Examples of the present disclosure describe systems and methods for detecting and mitigating stack pivoting exploits. In aspects, various “checkpoints” may be identified in software code. At each checkpoint, the current stack pointer, stack base, and stack limit for each mode of execution may be obtained. The current stack pointer for each mode of execution may be evaluated to determine whether the stack pointer falls within a stack range between the stack base and the stack limit of the respective mode of execution. When the stack pointer is determined to be outside of the expected stack range, a stack pivot exploit is detected and one or more remedial actions may be automatically performed.

公开(公告)号：US11965863B2

公开(公告)日：2024-04-23

申请号：US18070859

申请日：2022-11-29

Applicant: Waters Technologies Corporation

Inventor： Sylvain Gilles Cormier ,  Joseph D. Antocci ,  Francis Patrick Tracey ,  Charles H. Phoebe, Jr.

IPC: G01N30/24 ,  G01N30/20 ,  G01N30/38 ,  G01N30/02

CPC classification number: G01N30/20 ,  G01N30/24 ,  G01N30/38 ,  G01N2030/027 ,  G01N2030/207

Abstract: A liquid chromatography system includes a solvent delivery system, a sample manager including a sample delivery system in fluidic communication with the solvent delivery system, the sample delivery system configured to inject a sample from a sample-vial into a chromatographic flow stream, a liquid chromatography column located downstream from the sample delivery system, and a detector located downstream from the liquid chromatography column. The sample delivery system further includes a first needle drive including a first sample needle configured to extract the sample from the sample-vial and deliver the sample to the liquid chromatography column, and a first syringe in communication with the first sample needle configured to meter extraction of the sample from the sample-vial. The sample manager further includes a sample automation system that includes a second needle drive including a second sample needle configured to add a volume of reagent to the sample-vial.

公开(公告)号：US20180306759A1

公开(公告)日：2018-10-25

申请号：US16016866

申请日：2018-06-25

Applicant: DIONEX SOFTRON GMBH

Inventor： Hermann HOCHGRAEBER

IPC: G01N30/20 ,  G01N30/32 ,  G01N35/10 ,  G01N30/24 ,  G01N30/02

CPC classification number: G01N30/20 ,  G01N30/24 ,  G01N30/32 ,  G01N35/1097 ,  G01N2030/027 ,  G01N2030/201 ,  G01N2030/207

Abstract: A sample injection method for liquid chromatography is performed with an injection valve having a waste port, two sample loop ports, and two high-pressure ports. One high-pressure port can be connected to a pump and the other high-pressure port can be connected to a chromatography column. A sample loop is connected to one of the sample loop ports on one end and to a pump volume of a sample conveying device on the other end. A section of the sample loop can be separated to facilitate receiving a sample fluid in the sample loop. A control unit controls the injection valve and the sample conveying device. The sample injector allows a sample to be loaded into the sample loop and then pressurized to an operating pressure prior to injecting the sample into the chromatography column. The sample loop may also be isolated from the operating pressure for facilitating depressurization of the loop.

公开(公告)号：US20180306758A1

公开(公告)日：2018-10-25

申请号：US15959848

申请日：2018-04-23

Applicant: DIONEX SOFTRON GMBH

Inventor： Thomas WACHINGER

IPC: G01N30/20

CPC classification number: G01N30/20 ,  G01N30/22 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/207

Abstract: A sample pre-compression valve for liquid chromatography applications is described. The valve enables a sample pre-compression while the solvent pump continues to conduct solvent to the chromatography column. Furthermore, the sample pre-compression valve includes an INJECT position, a LOAD position and a PUMP PURGE position, in which all connecting grooves of the valve are flushed with liquid. A use of the sample pre-compression valve is described as part of a sampler for liquid chromatography applications.

公开(公告)号：US09964527B2

公开(公告)日：2018-05-08

申请号：US15190570

申请日：2016-06-23

Applicant: DIONEX SOFTRON GMBH

Inventor： Thomas Wachinger

IPC: G01N30/20 ,  G01N30/02

CPC classification number: G01N30/20 ,  G01N30/22 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/207

Abstract: A sample pre-compression valve for liquid chromatography applications is described. The valve enables a sample pre-compression while the solvent pump continues to conduct solvent to the chromatography column. Furthermore, the sample pre-compression valve includes an INJECT position, a LOAD position and a PUMP PURGE position, in which all connecting grooves of the valve are flushed with liquid. A use of the sample pre-compression valve is described as part of a sampler for liquid chromatography applications.

公开(公告)号：US09945762B2

公开(公告)日：2018-04-17

申请号：US14586882

申请日：2014-12-30

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Edwin E. Wikfors ,  Brian A. Bidlingmeyer ,  Klaus Witt

IPC: G01N30/06 ,  G01N1/28 ,  G01N30/20 ,  G01N30/36 ,  G01N30/34

CPC classification number: G01N1/28 ,  G01N30/20 ,  G01N30/36 ,  G01N2030/202 ,  G01N2030/207 ,  G01N2030/342

Abstract: A method and a system for introducing a sample into a mobile phase of a chromatography system is provided. The method includes initially directing the mobile phase directly into a separation unit of the chromatography system, bypassing a sample loop, the mobile phase including a combined solvent, metered from a pressurized first solvent and a second solvent; loading the sample into the sample loop, while the mobile phase continues to be directed directly into the separation unit; pressurizing the sample in the sample loop with the pressurized first solvent, while the mobile phase continues to be directed directly into the separation unit; and switching the sample loop into the mobile phase, thereby introducing the pressurized sample to the separation unit.

公开(公告)号：US20180038837A1

公开(公告)日：2018-02-08

申请号：US15730936

申请日：2017-10-12

Applicant: HITACHI HIGH-TECHNOLOGIES COPRORATION

Inventor： Shinya ITO ,  Shigeo MUTO

IPC: G01N30/20 ,  G01N30/24 ,  H01J49/04 ,  G01N35/08 ,  G01N30/00 ,  G01N30/72

CPC classification number: G01N30/20 ,  G01N30/24 ,  G01N30/7233 ,  G01N30/7266 ,  G01N35/08 ,  G01N2030/009 ,  G01N2030/207 ,  H01J49/0431

Abstract: Provided herein is a sample injection method that enables efficient injection of a trace sample solution while reducing the measurement time. A sample solution is injected into a sample loop with air layers disposed on both sides of the sample solution, and the total amount of the sample solution, including the air layers, is injected into a detector. The start and the end of data collection are determined from the detection signal intensity changes that occur upon the air layers being injected into the detector, and the velocity of the flowing liquid is increased to reduce the measurement time. A washing solution is injected after the air layer to improve the washing efficiency and reduce the washing time.

公开(公告)号：US20170343518A1

公开(公告)日：2017-11-30

申请号：US15608903

申请日：2017-05-30

Applicant: Agilent Technologies, Inc.

Inventor： Daniel Thielsch ,  Thomas Ortmann

IPC: G01N30/06 ,  G01N30/20 ,  G01N30/22

CPC classification number: G01N30/06 ,  F16K11/074 ,  G01N30/20 ,  G01N30/22 ,  G01N30/32 ,  G01N2030/201 ,  G01N2030/202 ,  G01N2030/207

Abstract: An injector, for injecting a fluidic sample into a flow path between a fluid drive and a sample separation unit, includes a sample accommodation volume, a sample drive, and a fluidic valve switchable to selectively couple the volume with the flow path or decouple the volume from the flow path. In an injection switching state, the fluid drive, the separation unit and the sample drive are coupled by the valve so that fluid driven by the sample drive and flowing from the volume to the separation unit and further fluid driven by the fluid drive and flowing from the fluid drive to the separation unit are combined at a fluidic connection upstream of the separation unit. A control unit controls a pressure of the fluid and/or the further fluid during injecting.

公开(公告)号：US20170176400A1

公开(公告)日：2017-06-22

申请号：US15129543

申请日：2014-10-22

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Sang-Won LEE ,  Hangyeore LEE

IPC: G01N30/46 ,  G01N30/20

CPC classification number: G01N30/468 ,  B01D15/1864 ,  G01N30/08 ,  G01N30/20 ,  G01N2030/009 ,  G01N2030/201 ,  G01N2030/202 ,  G01N2030/207

Abstract: A dual online liquid chromatography device according to an embodiment of the present invention comprises: a first pump for injecting a first solvent or a mixed solution containing the first solvent and a second solvent; a second pump for injecting the first solvent or the mixed solution containing the first and second solvents; a specimen intake valve connected to the first pump and a specimen injector for injecting a specimen; a column selection valve connected to the second pump and the specimen intake valve; and a dual column valve including a plurality of ports, one side of which is connected to the column selection valve and an opposite side of which is connected to a first column and a second column.

公开(公告)号：US09683975B2

公开(公告)日：2017-06-20

申请号：US14620924

申请日：2015-02-12

Applicant: IDEX Health & Science LLC

Inventor： Carl Sims

IPC: G01N30/32 ,  B01D15/08 ,  B01D15/42 ,  G01N30/20 ,  G01N30/46

CPC classification number: G01N30/32 ,  B01D15/08 ,  B01D15/1878 ,  B01D15/22 ,  B01D15/424 ,  G01N30/20 ,  G01N30/465 ,  G01N2030/027 ,  G01N2030/207 ,  G01N2030/208 ,  G01N2030/324

Abstract: A multi-dimensional liquid analysis system includes a first dimension system and a second dimension system, wherein outflow from the first dimension system is separated at a flow splitter under controlled conditions. The flow splitter separates the first dimension outflow into first and second split outlet flows, with one of the split outlet flows being metered to a designated flow rate with a flow metering device disposed downstream from the flow splitter. The flow metering device selectively closes or opens an outlet flow path to define a volumetric flow rate along that outlet flow path, so that the other split outlet flow is correspondingly controlled.