Method of Preparing Oxidized Starch Haemostatic Material

    公开(公告)号:US20180179301A1

    公开(公告)日:2018-06-28

    申请号:US15607561

    申请日:2017-05-29

    摘要: A method of preparing an oxidized starch haemostatic material, including adding a starch raw material to an external circulation pulsatile reactor; switching on a pump to allow inflow of dry air for drying the raw material; switching on a heat exchanger; vacuumizing the reactor; opening a nitrogen dioxide pipeline and a dry air pipeline; pumping in a mixed gas; controlling temperature at 0-120° C. by the heat exchanger; wherein nitrogen dioxide is contacted with the raw material to trigger a selective oxidation reaction and is continuously recycled; an airflow circulation switch is switched on and off at a pulsating ratio of 1:1-10 to carry out airflow pulsation; stopping inflow of nitrogen dioxide and continuing airflow circulation for 5-30 minutes; after completion of the reaction, adjusting to room temperature; vacuumizing the reactor and treating exhaust gas; allowing nitrogen gas to flow in for rinsing the replaced reactor until completion.

    Subcritical gas assisted drying of biopolymer material
    48.
    发明授权
    Subcritical gas assisted drying of biopolymer material 有权
    亚临界气体辅助干燥生物聚合物材料

    公开(公告)号:US09102765B2

    公开(公告)日:2015-08-11

    申请号:US13579054

    申请日:2011-02-18

    摘要: A method is provided for producing a dehydrated biopolymer powder, said method comprising the successive steps of: a) providing a filter cake comprising biopolymer material and 30 to 60 wt. % of water; b) contacting said filter cake with a pressurized gas to extract water from the filter cake, said pressurized gas having a pressure and a temperature below the critical point of the gas; c) separating water-containing pressurized gas from the dehydrated filter cake; and d) collecting a dehydrated biopolymer powder wherein the pressurized gas has a pressure of at least 0.6 MPa (6 bar) and up to 6 MPa (60 bar), and a temperature of 10 to 40° C.

    摘要翻译: 提供了一种用于生产脱水生物聚合物粉末的方法,所述方法包括以下连续步骤:a)提供包含生物聚合物材料的滤饼和30至60wt。 %的水; b)使所述滤饼与加压气体接触以从滤饼中提取水,所述加压气体具有低于气体临界点的压力和温度; c)从脱水滤饼中分离含水加压气体; 和d)收集脱水生物聚合物粉末,其中加压气体具有至少0.6MPa(6bar)和高达6MPa(60bar)的压力,以及10至40℃的温度。

    METHOD FOR PRODUCING STARCH GRANULES, AND ORALLY DISINITEGRATING TABLET
    49.
    发明申请
    METHOD FOR PRODUCING STARCH GRANULES, AND ORALLY DISINITEGRATING TABLET 有权
    用于生产淀粉颗粒的方法,以及用于消毒淀粉的方法

    公开(公告)号:US20150141525A1

    公开(公告)日:2015-05-21

    申请号:US14397042

    申请日:2013-04-23

    IPC分类号: A61K9/20

    摘要: A method for producing starch granules suitable as an excipient for an orally disintegrating tablet. Fluidized bed granulation is performed by spraying a starch paste in small amounts while a β-starch is being fluidized using an air-fluidized bed. Subsequently, fluidized bed drying is performed at a temperature equal to or higher than the gelatinization temperature of the β-starch. This yields starch granules having a high degree of gelatinization in comparison with the amount of α-starch adhered to the β-starch by the spraying of the starch paste. These starch granules alone impart satisfactory oral disintegratability and breaking strength to the tablet. Accordingly, when used as an excipient during tableting of orally disintegrating tablets, other auxiliary excipients such as saccharides or crystalline cellulose need not be added.

    摘要翻译: 一种适合作为口腔崩解片剂的赋形剂的淀粉颗粒的制造方法。 流化床造粒是通过在使用空气流化床流化的淀粉糊时少量喷洒淀粉糊来进行的。 随后,在等于或高于淀粉的糊化温度的温度下进行流化床干燥。 与通过喷雾淀粉糊粘附到淀粉上的α-淀粉的量相比,产生具有高糊化程度的淀粉颗粒。 这些淀粉颗粒单独赋予片剂令人满意的口服崩解性和断裂强度。 因此,当在口腔崩解片剂的压片期间用作赋形剂时,不需要加入其它辅助赋形剂如糖或结晶纤维素。

    Method of Producing Corn Starch by Enzymatic Process
    50.
    发明申请
    Method of Producing Corn Starch by Enzymatic Process 有权
    通过酶法生产玉米淀粉的方法

    公开(公告)号:US20120288900A1

    公开(公告)日:2012-11-15

    申请号:US13404983

    申请日:2012-02-24

    IPC分类号: C12P19/14

    摘要: A method of producing corn starch by enzymatic process involving: soaking the corn; crushing the corn, separating and washing embryo; fine grinding; washing and drying fiber; separating and drying protein; washing, dewatering and drying the starch. An enzyme preparation is added before the step of washing, dewatering and drying the starch; the enzyme preparation is cellulose, or xylanase, or combination of the cellulose and the xylanase; and addition of the enzyme preparation is from 0.001% to 0.08% by weight of the corn. Based on the technology of traditional wet process, the method of the present invention comprises a step of adding enzyme preparation in the process of separating the corn, which improves the effect and the efficiency of mechanical separation, and further improves the purity and yield of the substance separated while also reducing the energy consumption.

    摘要翻译: 一种通过酶法生产玉米淀粉的方法,包括:浸泡玉米; 粉碎玉米,分离洗涤胚胎; 精磨; 洗涤和干燥纤维; 分离和干燥蛋白质; 洗涤,脱水和干燥淀粉。 在洗涤,脱水和干燥淀粉的步骤之前加入酶制剂; 酶制剂是纤维素或木聚糖酶,或纤维素和木聚糖酶的组合; 并且酶制剂的添加量为玉米重量的0.001%至0.08%。 基于传统湿法的技术,本发明的方法包括在分离玉米的过程中加入酶制剂的步骤,提高了机械分离的效果和效率,进一步提高了纯度和产率。 物质分离同时也降低能耗。