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公开(公告)号：US11602910B2
公开(公告)日：2023-03-14
申请号：US16884536
申请日：2020-05-27
Applicant: Alcon Inc.
Inventor： Richard Charles Breitkopf , Changhong Yin , Steve Yun Zhang
Abstract: The invention relates to a pad printing instrument comprising an ink supply system capable of control the temperature, viscosity and colorant concentration of an ink in an ink cup. Such controls are achieved by continuously adding and mixing a cold ink having a composition identical to the ink in the ink cup but having a lower temperature. The continuous addition of a small amount of a cold ink into the ink cup could compensate heat generated by the friction between the ink cup and a cliché and could minimize the evaporation of a diluent in the ink and change in the concentration of colorants in the ink and ink viscosity. The invention also relates to use of a pad printing instrument comprising an ink supply system of the invention for producing colored hydrogel or silicone hydrogel contact lenses.
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公开(公告)号：US20220283338A1
公开(公告)日：2022-09-08
申请号：US17688041
申请日：2022-03-07
Applicant: Alcon Inc.
Inventor： Michelle Plavnik , Richard Charles Breitkopf , Steve Yun Zhang , Zahra Bassampour , Chandana Kolluru
Abstract: Described herein is a method for producing a contact lens comprising a central photochromic zone that has a diameter of about 13 mm or less and is concentric with the central axis of the contact lens. The method comprises: applying a first polymerizable fluid composition containing at least one photochromic compound on a central portion of the molding surface of a female mold half to form a circular layer; partially photocuring, in situ, the circular layer in the female mold half by using a visible light; dispensing a second polymerizable fluid composition over the partially-cured circular layer on the molding surface of the female mold half; and a step of thermally curing the second polymerizable fluid composition and the partially-cured circular layer immersed therein in the mold cavity formed between the the molding surfaces of the female mold half and a male mold half.
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公开(公告)号：US20220137433A1
公开(公告)日：2022-05-05
申请号：US17518423
申请日：2021-11-03
Applicant: Alcon Inc.
Inventor： Yuan Chang , Junhao Ge , Steve Yun Zhang , Michelle Plavnik , Augustine Twum Kumi
Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including an iniferter to form an unprocessed contact lens having iniferter moieties covalently incorporated into its polymer matrix and a step of iniferter-induced graft-polymerization of a photochromic vinylic monomer to the polymer matrix only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.
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公开(公告)号：US11254076B2
公开(公告)日：2022-02-22
申请号：US16429811
申请日：2019-06-03
Applicant: Alcon Inc.
Inventor： Junhao Ge , Daqing Wu , Richard Charles Breitkopf , Steve Yun Zhang , Augustine Twum Kumi
IPC: B29D11/00 , C08F226/10 , G02B1/04 , B29K83/00 , B29K105/00
Abstract: The invention provides a contact lens manufacturing method comprising a process for removing unprocessed molded silicone hydrogel contact lenses from mold halves in a relatively efficient and consistent manner. A method of the invention comprising the steps of formulating a lens formulation by dissolving/blending all polymerizable components in a mixture a hydrophobic acrylic monomer as a reactive diluent and an organic solvent as a non-reactive diluent at a weight ratio of least 0.24 (reactive diluent over the sum of reactive and non-reactive solvents) per gram of the polymerizable composition and using a relatively low ultrasonic vibration energy for delensing. This method of the invention can be easily implemented in a production environment for enhancing the production yield.
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公开(公告)号：US20210291469A1
公开(公告)日：2021-09-23
申请号：US17205148
申请日：2021-03-18
Applicant: Alcon Inc.
Inventor： Yang Zheng , Junhao Ge , Steve Yun Zhang
Abstract: The invention is generally related to a method for producing, in a relatively efficient and consistent manner, embedded or hybrid silicone hydrogel contact lenses, and also to unprocessed embedded or hybrid silicone hydrogel contact lenses, according to conventional cast-molding technologies. A method of the invention involve use of a polymeric non-reactive diluent in preparing a polymerizable composition for forming the silicone hydrogel material of the unprocessed embedded or hybrid silicone hydrogel contact lens, which is cast-molded with a lens mold. The unprocessed cast-molded embedded or hybrid silicone hydrogel contact lens has no or a minimal water-swelling degree, so that lens distortion or delamination during the hydration of the unprocessed embedded or hybrid silicone hydrogel contact lens.
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Patent Agency Ranking
公开(公告)号：US20210284806A1
公开(公告)日：2021-09-16
申请号：US17199158
申请日：2021-03-11
Applicant: Alcon Inc.
Inventor： Yuan Chang , Junhao Ge , Steve Yun Zhang , Weihong Lang
IPC: C08G77/388 , C08L83/08
Abstract: The invention provides a class of photochromic polydiorganosiloxane vinylic crosslinkers. Each of the photochromic polydiorganosiloxane vinylic crosslinkers of the invention comprise (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and photochromic siloxane unit having one methyl substituent and one organic substituent having a photochromic moiety that capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light; (2) two terminal ethylenically-unsaturated groups. The invention also provides a soft photochromic contact lens, especially a photochromic silicone hydrogel contact lens, which comprises a crosslinked polymeric material comprising repeating units of at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers. The invention further provides a method of producing a photochromic contact lens from a polymerizable composition comprising at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers.
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公开(公告)号：US20210131923A1
公开(公告)日：2021-05-06
申请号：US17087983
申请日：2020-11-03
Applicant: Alcon Inc.
Inventor： Yuan Chang , Ying Zheng , Junhao Ge , Steve Yun Zhang , Karen Belinda Sentell , Jinbo Dou
Abstract: The invention provides a method for imaging and thickness determination of coatings on coated contact lenses. The method comprises selectively staining a negatively-charged-groups-containing coating over the lens body of a coated contact lens by immersing the coated contact lens in an aqueous solution comprising a fluorescently-labeled polycationic polymer and having a pH of from about 6.5 to 8.0; orthogonally cutting the selectively-stained coated contact lens; and determining the thickness of the coating on the coated contact lens. In addition, the invention provides a method for selecting a candidate coating material comprising negatively charged groups for applying a coating with a desired thickness onto silicone hydrogel contact lenses and for optimizing a coating process for producing coated silicone hydrogel contact lenses with a desired thickness coating thereon.
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公开(公告)号：US12286501B2
公开(公告)日：2025-04-29
申请号：US18435562
申请日：2024-02-07
Applicant: Alcon Inc.
Inventor： Jinyu Huang , Frank Chang , Steve Yun Zhang , Feng Jing
IPC: C08L101/14 , C08F290/06 , C08G77/16 , C08G77/20 , C08G77/392 , C08L83/04 , G02B1/04 , C08G77/12
Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.
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公开(公告)号：US20250059330A1
公开(公告)日：2025-02-20
申请号：US18929889
申请日：2024-10-29
Applicant: Alcon Inc.
Inventor： Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , B29D11/00 , C08G77/12 , C08G77/14 , C08G77/20 , C08G77/388 , C08G77/392 , C08L83/10 , G02B1/04 , G02C7/04
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号：US12171871B2
公开(公告)日：2024-12-24
申请号：US17392448
申请日：2021-08-03
Applicant: ALCON INC.
Inventor： Junhao Ge , Steve Yun Zhang , Daqing Wu , Jing Cheng , Yuan Chang , Feng Jing , Jang-Shing Chiou , Stephen Raymond Perreault
Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.
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