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199 条记录 (耗时 0.023 秒)

    Grafting apparatus and method of using
    31.
    发明申请
    Grafting apparatus and method of using 失效
    嫁接装置及其使用方法

    公开(公告)号：US20040161547A1

    公开(公告)日：2004-08-19

    申请号：US10371043

    申请日：2003-02-19

    申请人： SurModics, Inc.

    发明人： Mark F. Carlson ,  Steven J. Porter ,  Sean M. Stucke ,  Ralph A. Chappa

    IPC分类号： B05D003/06

    CPC分类号： B05C3/109 ,  B05C9/14 ,  B05D1/18 ,  B05D3/061 ,  B05D2258/02

    摘要： This invention provides a coating apparatus and methods for coating a device, such as an industrially or medically applicable device. The apparatus is suitable for providing a coating using a photoactivatable compound and a polymerizable compound. In another aspect, the apparatus and methods are useful for coating a device wherein the surface of the device has small pores or apertures. The apparatus includes of containers suitable for holding the object to be coated and the coating solution, a gas supply source for supplying gas to solution, an irradiation station for providing light used in the coating process, and a conveyor mechanism to direct the containers to and from the irradiation station.

    摘要翻译： 本发明提供一种涂覆装置和涂覆装置的方法，例如工业上或医学上适用的装置。 该装置适用于使用可光活化化合物和可聚合化合物提供涂层。 在另一方面，该装置和方法可用于涂覆装置，其中该装置的表面具有小的孔或孔。 该装置包括适于保持待涂覆物体和涂布溶液的容器，用于向溶液供应气体的气体供应源，用于提供在涂布过程中使用的光的照射台，以及输送机构， 从照射站。

    Replicable probe array
    32.
    发明申请
    Replicable probe array 审中-公开
    可复制探针阵列

    公开(公告)号：US20030170914A1

    公开(公告)日：2003-09-11

    申请号：US10357679

    申请日：2003-02-03

    申请人： SurModics, Inc

    发明人： Patrick E. Guire ,  Melvin J. Swanson

    IPC分类号： C12Q001/68 ,  G01N033/543

    CPC分类号： C12Q1/6837 ,  B01J19/0046 ,  B01J2219/005 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00648 ,  B01J2219/00659 ,  B01J2219/00722 ,  C40B40/06 ,  Y10S436/807 ,  Y10S436/809 ,  Y10S977/849

    摘要： A system for producing substantially identical specific binding ligand (e.g., nucleic acid) probe arrays, for instance, by preparing and replicating an original master array and/or by providing a reusable assay array that is capable of being regenerated. In one embodiment the system includes the preparation and use of a) a master array surface having address sequences immobilized in the form of a patterned, and optionally random, array, b) a multi-ligand conjugate having a binding domain complementary to an address sequence, a binding domain complementary to a target sequence, and a third ligand for use in forming (e.g., by binding or polymerization) the conjugates into or onto the surface of assay array, which can be used with or upon disassociation of the address and its complementary sequences.

    摘要翻译： 用于制备基本相同的特异性结合配体（例如，核酸）探针阵列的系统，例如通过制备和复制原始主阵列和/或通过提供能够再生的可重复使用的分析阵列。 在一个实施方案中，该系统包括a）主阵列表面的制备和使用，该主阵列表面具有以图案化和任选的阵列的形式固定的地址序列，b）具有与地址序列互补的结合结构域的多配体缀合物 ，与靶序列互补的结合结构域，以及用于将缀合物形成（例如通过结合或聚合）到测定阵列表面中或表面上的第三配体，其可以在解除地址及其使用时使用 互补序列。

    Insertable medical device system with plaque treatment portion and methods of using
    35.
    发明授权
    Insertable medical device system with plaque treatment portion and methods of using 有权

    公开(公告)号：US11504141B2

    公开(公告)日：2022-11-22

    申请号：US16687256

    申请日：2019-11-18

    申请人： Surmodics, Inc.

    发明人： Charlie Olson

    IPC分类号： A61B17/22 ,  A61B17/3207 ,  A61M25/10 ,  A61B17/32 ,  A61B17/00

    摘要： The disclosure provides plaque treatment catheter assemblies for the treatment of arterial plaques and removal of clots. One assembly includes a second catheter tube movable within a first catheter tube, and an expansion member movable within the second tube. The second catheter tube has one or more distally-disposed and outwardly-expandable plaque treatment portion(s). Another assembly includes a catheter tube and at least one channel(s) within the catheter. The channel includes an elongate member with a distally-disposed plaque scoring or clot retrieval member. Optionally, the assembly includes an expandable member that can cause movement of the scoring member.

    COATING SYSTEMS FOR MEDICAL DEVICES
    39.
    发明申请
    COATING SYSTEMS FOR MEDICAL DEVICES 有权

    公开(公告)号：US20210220866A1

    公开(公告)日：2021-07-22

    申请号：US17149390

    申请日：2021-01-14

    申请人： Surmodics, Inc.

    发明人： Ralph A. Chappa ,  Michael Militello

    IPC分类号： B05C11/10 ,  A61L29/08 ,  B05C11/08

    摘要： Aspects herein relate to coating apparatus and methods for coating medical devices. In an embodiment, a coating system is included having a valve, a fluid supply reservoir in fluid communication with the valve, a reciprocating positive displacement pump in fluid communication with the valve, and a fluid applicator in fluid communication with the three-way valve. The valve can be configured to assume a first fluid transport state and a second fluid transport state, wherein the valve provides fluid communication between the fluid supply reservoir and the reciprocating positive displacement pump when in the first fluid transport state for filling of the reciprocating positive displacement pump, and wherein the valve provides fluid communication between the reciprocating positive displacement pump and the fluid applicator when in the second fluid transport state for applying a coating suspension to a medical device surface. Other embodiments are also included herein.

    Two-part insertion tool and methods
    40.
    发明授权
    Two-part insertion tool and methods 有权

    公开(公告)号：US10806904B2

    公开(公告)日：2020-10-20

    申请号：US15467554

    申请日：2017-03-23

    申请人： Surmodics, Inc.

    发明人： Bruce M. Jelle ,  Joram Slager ,  Joseph Schmidt McGonigle ,  Nathan A. Lockwood

    IPC分类号： A61M25/06 ,  A61M25/00 ,  A61M39/06

    摘要： Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. The guide sheath can include a flared proximal end. The guide sheath can further include a central lumen. The guide sheath can further include a locking notch disposed on the inner surface between the proximal end and the distal end. The protection tube can include a flared proximal end. A portion of the protection tube can be situated within the central lumen of the guide sheath. The flared proximal end of the protection tube can be sized to fit within the locking notch and can have an outer diameter larger than portions of the inner surface immediately adjacent to the locking notch. Other embodiments are also included herein.