公开(公告)号：US20100264520A1

公开(公告)日：2010-10-21

申请号：US12810135

申请日：2008-11-28

Applicant: Naoki Ogawa

Inventor： Naoki Ogawa

IPC: H01L23/36 ,  H01L23/544

CPC classification number: H01L23/473 ,  H01L23/3735 ,  H01L24/48 ,  H01L24/49 ,  H01L25/072 ,  H01L2224/32225 ,  H01L2224/48137 ,  H01L2224/49175 ,  H01L2224/73265 ,  H01L2924/00014 ,  H01L2924/01004 ,  H01L2924/01012 ,  H01L2924/01078 ,  H01L2924/1305 ,  H01L2924/13055 ,  H01L2924/00 ,  H01L2224/45099 ,  H01L2224/45015 ,  H01L2924/207

Abstract: Provided is a semiconductor module wherein a stress relaxing layer is arranged between a ceramic substrate, upon which semiconductor elements are mounted, and a cooling device on the rear side of the ceramic substrate; and the ceramic substrate, the cooling device and the stress relaxing layer are integrally formed. Furthermore, the stress relaxing layer is separated into a plurality of separated sections by two slits. Furthermore, the slits are positioned between the semiconductor elements when viewed from the thickness direction of the stress relaxing layer and not in a projection region of the semiconductor element.

Abstract translation: 提供了一种半导体模块，其中应力缓和层布置在陶瓷基板之间，其上安装有半导体元件和陶瓷基板的后侧上的冷却装置; 陶瓷基板，冷却装置和应力缓和层一体形成。 此外，应力缓和层通过两个狭缝分离成多个分离的部分。 此外，当从应力缓和层的厚度方向而不是在半导体元件的投影区域中时，狭缝位于半导体元件之间。

公开(公告)号：US07605226B2

公开(公告)日：2009-10-20

申请号：US11276738

申请日：2006-03-13

Applicant: Atsuko Fujisawa ,  Toru Yamakawa ,  Kamon Shirakawa ,  Chitose Orii ,  Naoki Ogawa

Inventor： Atsuko Fujisawa ,  Toru Yamakawa ,  Kamon Shirakawa ,  Chitose Orii ,  Naoki Ogawa

IPC: A61K38/04 ,  A07K14/00

CPC classification number: C12N9/6489 ,  A61K38/00 ,  A61K2039/505 ,  C07K14/705 ,  C07K16/40 ,  C07K2317/76

Abstract: The purpose of the present invention is to provide a novel protein involved in adhesion and fusion between myoblasts in the course of the formation of byotube. The present invention relates to Meltrins, which a membrane protein having fusion, adhesion and aggregation activity of cells, especially myoblast; and to polypeptides of their domains, DNAs encoding them, antisense RNA for these DNAs, various antibodies to Meltrins and the polypeptides of their domains, expression vectors containing these DNAs, and transformants by these vectors; as well as to the process for producing Meltrins and the polypeptides of their domains using those transformants and medical compositions comprising Meltrins or antagonist against them as an effective ingredient.

公开(公告)号：US20070197512A1

公开(公告)日：2007-08-23

申请号：US11627439

申请日：2007-01-26

Applicant: Teruhiko Inoue ,  Toshihiro Kiguchi ,  Kazuyuki Hirata ,  Yuko Shinagawa ,  Naoki Ogawa ,  Katsuya Deai

Inventor： Teruhiko Inoue ,  Toshihiro Kiguchi ,  Kazuyuki Hirata ,  Yuko Shinagawa ,  Naoki Ogawa ,  Katsuya Deai

IPC: A61K31/5415 ,  A61K31/538 ,  C07D279/16 ,  C07D265/36

CPC classification number: C07D265/36 ,  C07D279/16

Abstract: Provision of a superior URAT1 activity inhibitor effective for the treatment and the like of a pathology involving uric acid, such as hyperuricemia, gouty tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urinary lithiasis, renal dysfunction, coronary heart disease, ischemic cardiac diseases and the like. A URAT1 activity inhibitor containing a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof, or a solvate thereof as an active ingredient: wherein each symbol is as defined in the specification.

Abstract translation: 提供一种有效治疗尿酸的病例的高级URAT1活性抑制剂，如高尿酸血症，痛风，急性痛风性关节炎，慢性痛风性关节炎，痛肾，尿结石，肾功能不全，冠心病，缺血性 心脏病等。 含有下述通式[1]表示的化合物或其药学上可接受的盐或其溶剂合物作为有效成分的URAT1活性抑制剂：其中每个符号如说明书中所定义。

公开(公告)号：US20060135572A1

公开(公告)日：2006-06-22

申请号：US11286378

申请日：2005-11-25

Applicant: Yuko Shinagawa ,  Teruhiko Inoue ,  Toshihiro Kiguchi ,  Taku Ikenogami ,  Naoki Ogawa ,  Takashi Nakagawa ,  Masanori Shindo ,  Yuki Soejima

Inventor： Yuko Shinagawa ,  Teruhiko Inoue ,  Toshihiro Kiguchi ,  Taku Ikenogami ,  Naoki Ogawa ,  Takashi Nakagawa ,  Masanori Shindo ,  Yuki Soejima

IPC: A61K31/426 ,  A61K31/381 ,  A61K31/138 ,  C07D333/22 ,  C07D277/22

CPC classification number: C07D257/04 ,  C07C217/28 ,  C07C311/51 ,  C07D277/56 ,  C07D285/08 ,  C07D333/38 ,  C07F9/3834 ,  C07F9/4021

Abstract: The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the description.

Abstract translation: 本发明提供具有钙敏感受体拮抗作用的化合物，含有该化合物，特别是钙受体拮抗剂的药物组合物和用于骨质疏松症的治疗药物。 由下式（1）表示的化合物，其药学上可接受的盐或其光学活性形式：其中每个符号如说明书中所定义。

公开(公告)号：US06969907B2

公开(公告)日：2005-11-29

申请号：US10262865

申请日：2002-10-03

Applicant: Makoto Imai ,  Naoki Ogawa ,  Yuji Yagi ,  Takashi Kojima ,  Yasushi Yamada

Inventor： Makoto Imai ,  Naoki Ogawa ,  Yuji Yagi ,  Takashi Kojima ,  Yasushi Yamada

IPC: H01L23/36 ,  H01L23/367 ,  H01L25/07 ,  H01L23/34 ,  H01L23/02 ,  H01L23/28 ,  H01L23/38 ,  H01L23/40

CPC classification number: H01L23/3672 ,  H01L25/072 ,  H01L2224/32225 ,  H01L2224/32245 ,  H01L2224/33181 ,  H01L2924/1305 ,  H01L2924/13055 ,  Y10S257/93 ,  H01L2924/00

Abstract: A first electronic device, a second electronic device which generates less heat than the first electric device, and an electrode are connected by a heat leveling plate formed of an electrically conductive material having high thermal conductivity. A heat radiation plate is provided below an insulated substrate to which the first and second electronic devices are mounted. The second electronic device is cooled by a heat radiation path which extends through the insulated substrate and the heat radiation plate and a heat radiation path which extends through the second electronic device and the electrode to the heat radiation plate. The first and the second electronic device have substantially the same temperature due to heat radiation through the heat leveling plate. As a result, cooling effect of the electronic devices can be enhanced.

Abstract translation: 第一电子装置，比第一电气装置产生的热量少的第二电子装置和电极通过由具有高导热性的导电材料形成的热平衡板连接。 散热板设置在安装有第一和第二电子设备的绝缘基板的下方。 第二电子设备被延伸穿过绝缘基板和散热板的热辐射路径和通过第二电子设备和电极延伸到散热板的散热路径来冷却。 第一和第二电子装置由于通过热平整板的热辐射而具有基本相同的温度。 结果，可以提高电子设备的冷却效果。

公开(公告)号：USD349504S

公开(公告)日：1994-08-09

申请号：US10789

申请日：1993-07-19

Applicant: Suehiro Mizukawa ,  Naoki Ogawa ,  Susumu Ohtani

Designer： Suehiro Mizukawa ,  Naoki Ogawa ,  Susumu Ohtani

公开(公告)号：US4662317A

公开(公告)日：1987-05-05

申请号：US852169

申请日：1986-04-15

Applicant: Naoki Ogawa

Inventor： Naoki Ogawa

IPC: F01P3/20 ,  F01P3/22 ,  F01P7/14 ,  F01P11/00 ,  F01P11/18

CPC classification number: F01P11/18 ,  F01P3/2271

Abstract: In order to simplify the control and construction of the cooling system in a manner which avoids the need for costly electromagnetic valves and control circuits such as microprocessor and the like, a reservoir in which coolant is stored is arranged to constantly communicate with a lower portion of a cooling circuit which includes the coolant jacket and the radiator in which the coolant vapor is condensed. A small coolant pump returns condensate from the radiator to the coolant jacket in response to a temperature sensor disposed in the coolant jacket. A cooling fan or like device is operated in response to a second temperature sensor disposed at the bottom of the radiator. The reservoir communicates with the ambient atmosphere through a relief valve which remains closed until a predetermined positive or negative pressure differential prevails between the ambient atmosphere and the interior of the reservoir.

Abstract translation: 为了简化冷却系统的控制和构造，以避免需要昂贵的电磁阀和诸如微处理器等的控制电路，其中存储有冷却剂的储存器被布置成与下一部分 冷却回路，其包括冷却剂套和冷却剂蒸气冷凝的散热器。 响应于设置在冷却剂护套中的温度传感器，小型冷却剂泵将冷凝物从散热器返回到冷却剂护套。 响应于设置在散热器底部的第二温度传感器操作冷却风扇或类似装置。 储存器通过安全阀与环境大气连通，安全阀保持关闭，直到环境大气和储存器内部之间存在预定的正或负压差。

公开(公告)号：US4630573A

公开(公告)日：1986-12-23

申请号：US779395

申请日：1985-09-23

Applicant: Naoki Ogawa ,  Takao Kubozuka ,  Yoshinori Hirano

Inventor： Naoki Ogawa ,  Takao Kubozuka ,  Yoshinori Hirano

IPC: F01P7/14 ,  F01P3/22 ,  F01P11/18

CPC classification number: F01P3/2285 ,  F01P11/18

Abstract: In order to obviate vapor locking and subsequent cavitation of a pump which returns coolant vapor condensate from a radiator to the coolant jacket of an evaporative type cooled internal combustion engine and maintains the highly heated structure of the engine immersed in a predetermined depth of liquid coolant, the load on the pump is sensed by determining the amount of electrical current the pump is drawing and in the event that the load is at a level indicative of pump cavitation the connection between the radiator and the pump is interrupted and communication between a reservoir and the pump is established so as to introduce cool liquid coolant into the induction port of the pump.

Abstract translation: 为了消除将冷却剂蒸汽冷凝物从散热器返回到蒸发式冷却内燃机的冷却剂套管的泵的蒸气锁定和随后的气蚀，并且将发动机的高度加热的结构保持在预定深度的液体冷却剂中， 通过确定泵正在绘制的电流量来感测泵上的负载，并且在负载处于表示泵气蚀的水平的情况下，散热器和泵之间的连接被中断，并且储存器和泵 建立泵以将冷却的液体冷却剂引入泵的进气口。

公开(公告)号：US4628872A

公开(公告)日：1986-12-16

申请号：US784174

申请日：1985-09-27

Applicant: Naoki Ogawa ,  Takao Kubozuka

Inventor： Naoki Ogawa ,  Takao Kubozuka

IPC: B60H1/08 ,  F01P3/22 ,  F01P5/14 ,  F01P7/14 ,  F01P7/16

CPC classification number: F01P3/2285 ,  B60H1/08 ,  F01P5/14 ,  F01P7/167

Abstract: In the event that the normal coolant return pump of an evaporative type automotive cooling system malfunctions, a back-up system establishes fluid communication between the cooling circuit and the circulation pump of a heater circuit in a manner which enables the heater circulation pump to be used in place of the normal unit until such time as repair can be effected.

Abstract translation: 在蒸发式汽车冷却系统的正常冷却剂回流泵发生故障的情况下，备用系统以能够使用加热器循环泵的方式在冷却回路和加热器回路的循环泵之间建立流体连通 代替正常单位，直到可以进行修理。

公开(公告)号：US4605164A

公开(公告)日：1986-08-12

申请号：US777019

申请日：1985-09-17

Applicant: Yoshimasa Hayashi ,  Naoki Ogawa

Inventor： Yoshimasa Hayashi ,  Naoki Ogawa

IPC: F01P3/20 ,  B60H1/00 ,  B60H1/08 ,  B60H1/14 ,  F01P3/22 ,  F01P7/16 ,  B60H1/02

CPC classification number: B60H1/00314 ,  F01P3/2285 ,  F01P7/167 ,  F01P2060/08

Abstract: A cabin heating arrangement is associated with an evaporative type engine cooling system and arranged so that immediately after a cold engine start when the cooling circuit of the engine is completely filled with liquid coolant coolant is inducted from a first port located immediately adjacent the most highly heated structure of the engine and pumped through the core of the cabin heater. Upon the coolant temperature rising sufficiently, coolant vapor is inducted from a second port located above the first one and introduced into the heater core.

Abstract translation: 机舱加热装置与蒸发型发动机冷却系统相关联并且布置成使得在发动机的冷却回路完全充满液体冷却剂之后立即冷起动，冷却剂从位于紧邻最高度加热 发动机的结构并通过机舱加热器的核心泵送。 当冷却剂温度充分上升时，冷却剂蒸汽从位于第一端上方的第二端口引入并被引入加热器芯中。