公开(公告)号：US20060068491A1

公开(公告)日：2006-03-30

申请号：US11227245

申请日：2005-09-16

申请人： Yoshihiko Makino ,  Yoshiki Sakaino ,  Yukio Sudo ,  Yoshihiko Abe

发明人： Yoshihiko Makino ,  Yoshiki Sakaino ,  Yukio Sudo ,  Yoshihiko Abe

IPC分类号： C12M1/34 ,  C07H21/04

CPC分类号： B01L3/502753 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/0631 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0418 ,  B01L2400/0487

摘要： A microdevice for performing a method for separating and purifying a nucleic acid, the microdevice comprising: at least one opening; and at least one channel for passing a sample solution, wherein the method comprises: (A) a step of bringing a nucleic acid-containing sample solution into contact with a nucleic acid-adsorbing support having a function of adsorbing a nucleic acid; (B) a step of washing the nucleic acid-adsorbing support with a washing solution in a state of a nucleic acid being adsorbed to the support; and (C) a step of desorbing the nucleic acid from the nucleic acid-adsorbing support by a recovering solution, thereby purifying the nucleic acid; an apparatus for utilizing the microdevice; and a reagent kit for use in the microdevice.

摘要翻译： 一种用于进行分离和纯化核酸的方法的微型装置，所述微型装置包括：至少一个开口; 和用于通过样品溶液的至少一个通道，其中所述方法包括：（A）使含核酸样品溶液与具有吸附核酸功能的核酸吸附载体接触的步骤; （B）在被吸附在所述载体上的核酸的状态下用洗涤液洗涤所述核酸吸附载体的工序; 和（C）通过回收溶液从核酸吸附载体解吸核酸的步骤，从而纯化核酸; 一种利用微型装置的装置; 和用于微型装置的试剂盒。

公开(公告)号：US06664051B1

公开(公告)日：2003-12-16

申请号：US09706405

申请日：2000-11-03

申请人： Hiroshi Shinoki ,  Yukio Sudo ,  Osamu Seshimoto

发明人： Hiroshi Shinoki ,  Yukio Sudo ,  Osamu Seshimoto

IPC分类号： C07H2104

CPC分类号： C40B40/06 ,  B01J2219/00608 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00677 ,  B82Y30/00 ,  C40B50/06

摘要： A DNA chip or its analogue composed of nucleotide derivatives attached to a solid carrier is prepared by method of bringing nucleotide derivatives having a reactive group at each one terminal into contact with a solid carrier having thereon reactive groups in an aqueous phase in the presence of a transferase which is capable of producing a covalent bond by rearrangement of the reactive group of the nucleotide derivative and the reactive group of the solid carrier.

摘要翻译： 通过以下方法制备DNA芯片或其由连接于固体载体上的核苷酸衍生物组成的类似物的方法：使得在每个末端具有反应性基团的核苷酸衍生物与其中具有反应性基团的固体载体在水相中存在下接触 能够通过核苷酸衍生物的反应性基团和固体载体的反应性基团的重排而产生共价键的转移酶。

公开(公告)号：US6164731A

公开(公告)日：2000-12-26

申请号：US116605

申请日：1998-07-17

申请人： Chiharu Nakazawa ,  Yukinori Otsuka ,  Yukio Sudo

发明人： Chiharu Nakazawa ,  Yukinori Otsuka ,  Yukio Sudo

IPC分类号： B60T8/1761 ,  B60T8/24 ,  B60T8/40 ,  B60T8/48

CPC分类号： B60T8/4881 ,  B60T8/4031 ,  Y10S303/10

摘要： An automotive brake system comprises a sump fluidly disposed in a housing, constructing a brake unit, and in the middle of a suction circuit of a pressure apply device including at least a pressure apply pump. During vehicle dynamics control or during vehicle stability control, the pressure apply rapidly sucks the brake fluid stored in the sump and quickly performs a pressure apply action, irrespective of the distance between the brake unit and a brake-fluid source. This ensures a smooth brake-fluid supply to the suction circuit of a return pump returning the brake fluid from the wheel-brake cylinder to the brake circuit upstream of a fluid-pressure control valve unit.

摘要翻译： 汽车制动系统包括流体地设置在壳体中的槽，构成制动单元，以及包括至少一个压力泵的压力施加装置的抽吸回路的中间。 在车辆动力学控制期间或在车辆稳定性控制期间，施加的压力快速吸收存储在贮槽中的制动液，并且与制动单元和制动液源之间的距离无关地快速地执行施加压力的动作。 这确保了向回流泵的抽吸回路提供平稳的制动液供给，该回流泵将制动液从制动轮缸返回到流体压力控制阀单元上游的制动回路。

公开(公告)号：US5965605A

公开(公告)日：1999-10-12

申请号：US999348

申请日：1997-12-29

申请人： Y.-S. Edmond Cheng ,  Yuan Liu ,  John Chu ,  Jean-Pierre Kinet ,  Marie-Helene Jouvin ,  Yukio Sudo ,  Xiuqi Qian

发明人： Y.-S. Edmond Cheng ,  Yuan Liu ,  John Chu ,  Jean-Pierre Kinet ,  Marie-Helene Jouvin ,  Yukio Sudo ,  Xiuqi Qian

IPC分类号： A61K31/352 ,  A61K31/4433 ,  C07D311/82 ,  A61K31/35

CPC分类号： A61K31/352 ,  A61K31/4433 ,  C07D311/82

摘要： Disclosed are chemical agents with unexpected activity to inhibit the interactions between human immunoglobulin E (IgE) and its receptor (Fc.epsilon.RI) which interactions are known to be involved in triggering allergic responses. The agents may be used to module the allergic response in the treatment of various clinical conditions, including rhinitis, asthma, urticaria, atopic dermatitis, and anaphylacric shock. The agents can be formulated for oral, topical or parenteral administration.

摘要翻译： 公开了具有意想不到的活性以抑制人免疫球蛋白E（IgE）及其受体（FcεRI）之间的相互作用的化学试剂，这些相互作用已知涉及触发过敏反应。 这些药剂可用于模块化治疗各种临床状况的过敏反应，包括鼻炎，哮喘，荨麻疹，特应性皮炎和过敏性休克。 所述药剂可以配制用于口服，局部或肠胃外给药。

公开(公告)号：US5374113A

公开(公告)日：1994-12-20

申请号：US68673

申请日：1993-05-28

申请人： Ichiro Kaneda ,  Yukio Sudo

发明人： Ichiro Kaneda ,  Yukio Sudo

IPC分类号： B60T8/42 ,  B60T8/50 ,  B60T15/46

CPC分类号： B60T8/4291 ,  B60T8/5037

摘要： A brake-fluid reflux type anti-skid brake control system for an automotive vehicle, comprises a main brake-fluid line fluidly disposed between a master cylinder and a wheel cylinder for supplying a brake fluid from the master cylinder to the wheel cylinder during usual braking, a brake-fluid reflux line arranged in parallel with the main line for returning the brake fluid from the wheel cylinder to the master cylinder side during operation of the system, directional control valves arranged for controlling the respective fluid flow in the main brake-fluid line and in the reflux line, depending upon a skidding condition of a vehicle wheel, and a plunger type control valve arranged between the outlet port of the master cylinder and an upstream junction of the main line and the reflux line. The control valve is responsive to a fluid pressure representing whether the anti-skid brake control system is in an operative state or in an inoperative state, in a manner so as to provide a constricted brake-fluid flow therethrough to the wheel cylinder in the operative state of the system and to provide a full brake-fluid flow therethrough to the wheel cylinder in the inoperative state of the system.

摘要翻译： 一种用于机动车辆的制动液回流式防滑制动控制系统，包括流体地设置在主缸和轮缸之间的主制动液管线，用于在通常制动期间将制动液从主缸提供给轮缸 ，制动液回流管线，其与所述主管线平行设置，用于在系统运行期间将制动液体从轮缸返回到主缸侧;布置成用于控制主制动流体中的相应流体流动的方向控制阀 取决于车轮的打滑条件以及布置在主缸的出口与主管和回流管的上游接合点之间的柱塞型控制阀。 控制阀响应于表示防滑制动控制系统是否处于工作状态或处于非工作状态的流体压力，以便提供缩小的制动液流动通过其中的操作的轮缸 并且在系统的非操作状态下提供通过其到达轮缸的完整的制动液流体。

公开(公告)号：US07793712B2

公开(公告)日：2010-09-14

申请号：US11844339

申请日：2007-08-23

申请人： Tsutomu Yamate ,  Hiroshi Inoue ,  Jiro Takeda ,  Yukio Sudo ,  Emmanuel Desroques ,  Satoru Umemoto

发明人： Tsutomu Yamate ,  Hiroshi Inoue ,  Jiro Takeda ,  Yukio Sudo ,  Emmanuel Desroques ,  Satoru Umemoto

IPC分类号： E21B29/02 ,  E21B47/00 ,  E21B49/00 ,  E21B47/12

CPC分类号： E21B47/00

摘要： A downhole tool, configured to be suspended in a borehole traversing an earth formation, includes a downhole data acquisition system placed in the tool body and electrically connected to an electric power generator at the formation surface. The downhole data acquisition system includes a sensor for detecting local conditions in the borehole, and a transducer for transducing the voltage of an input signal from high to low or low to high. The transducer having a gallium nitride or silicon carbide based discrete semiconductor device.

摘要翻译： 构造成悬挂在穿过地层的钻孔中的井下工具包括放置在工具主体中并与形成表面处的发电机电连接的井下数据采集系统。 井下数据采集系统包括用于检测钻孔中的局部状况的传感器，以及用于将输入信号的电压从高到低转换为高的换能器。 换能器具有基于氮化镓或碳化硅的分立半导体器件。

公开(公告)号：US07407578B2

公开(公告)日：2008-08-05

申请号：US11185822

申请日：2005-07-21

申请人： Yoshiki Sakaino ,  Yukio Sudo

发明人： Yoshiki Sakaino ,  Yukio Sudo

IPC分类号： B01D29/00

CPC分类号： B01D39/2017 ,  B01D2239/0492 ,  G01N33/491

摘要： A liquid filtering instrument 10 according to the present invention achieves filtered liquid by pressure-reduced filtration, and it comprises a filter member 12 in which a liquid filter 15 is accommodated, and a holder member 14 for stocking filtered liquid passed through the liquid filter 15, wherein the filter member 12 and the holder member 14 are formed in capable of being fitted so as to be kept substantially air-tight and water-tight under pressure reduced state.

摘要翻译： 根据本发明的液体过滤装置10通过减压过滤实现过滤液体，并且其包括其中容纳有液体过滤器15的过滤构件12和用于储存通过液体过滤器15的过滤液体的保持构件14 ，其中过滤构件12和保持器构件14形成为能够被装配成在压力降低状态下基本上保持气密性和水密性。

公开(公告)号：US20080047751A1

公开(公告)日：2008-02-28

申请号：US11844339

申请日：2007-08-23

申请人： Tsutomu Yamate ,  Hiroshi Inoue ,  Jiro Takeda ,  Yukio Sudo ,  Emmanuel Desroques ,  Satoru Umemoto

发明人： Tsutomu Yamate ,  Hiroshi Inoue ,  Jiro Takeda ,  Yukio Sudo ,  Emmanuel Desroques ,  Satoru Umemoto

IPC分类号： E21B49/00

CPC分类号： E21B47/00

摘要： A downhole tool, configured to be suspended in a borehole traversing an earth formation, includes a downhole data acquisition system placed in the tool body and electrically connected to an electric power generator at the formation surface. The downhole data acquisition system includes a sensor for detecting local conditions in the borehole, and a transducer for transducing the voltage of an input signal from high to low or low to high. The transducer having a gallium nitride or silicon carbide based discrete semiconductor device.

摘要翻译： 构造成悬挂在穿过地层的钻孔中的井下工具包括放置在工具主体中并与形成表面处的发电机电连接的井下数据采集系统。 井下数据采集系统包括用于检测钻孔中的局部状况的传感器，以及用于将输入信号的电压从高到低转换为高的换能器。 换能器具有基于氮化镓或碳化硅的分立半导体器件。

公开(公告)号：US20060117888A1

公开(公告)日：2006-06-08

申请号：US11269628

申请日：2005-11-09

申请人： Isamu Tsubono ,  Junichi Tamamoto ,  Makoto Yamakado ,  Tooru Takahashi ,  Yukio Sudo

发明人： Isamu Tsubono ,  Junichi Tamamoto ,  Makoto Yamakado ,  Tooru Takahashi ,  Yukio Sudo

IPC分类号： B62D5/04

CPC分类号： F16H25/2266 ,  B62D5/0427 ,  B62D5/0451 ,  F16H2025/2078 ,  Y10T74/19791 ,  Y10T74/19902

摘要： Revolving rollers, each provided on an outer peripheral surface thereof with revolving roller grooves extending therearound, are caused to mesh with a rack rod thread of a central rack rod with an axial angle over a lead angle of the rack rod thread and arranged for rotation on a holder member to be twisted. The holder member is rotated round the rack rod by a motor to translate the rack rod. A large thrust can be generated while ensuring a high reliability since a high efficiency is achieved by realizing rolling contact in set points of mesh of the rack rod thread and the revolving roller grooves, points of mesh are made planar, and interference in other points than the points of mesh can be suppressed. Also, play can be restricted by assembling the revolving rollers to the rack rod thread while applying torque in a direction, in which the axial angle is increased.

摘要翻译： 该机构具有支架，该支架围绕机架杆相对于齿杆杆支撑。 旋转辊（22,24）支撑在支架上旋转。 每个辊相对于齿条的轴线的轴向角度大于齿条的螺纹的导程角。 每个辊具有环形表面，其与齿条的螺纹的侧面啮合在外周表面上。

公开(公告)号：US20060018798A1

公开(公告)日：2006-01-26

申请号：US11185822

申请日：2005-07-21

申请人： Yoshiki Sakaino ,  Yukio Sudo

发明人： Yoshiki Sakaino ,  Yukio Sudo

IPC分类号： B01L11/00

CPC分类号： B01D39/2017 ,  B01D2239/0492 ,  G01N33/491

摘要： A liquid filtering instrument 10 according to the present invention achieves filtered liquid by pressure-reduced filtration, and it comprises a filter member 12 in which a liquid filter 15 is accommodated, and a holder member 14 for stocking filtered liquid passed through the liquid filter 15, wherein the filter member 12 and the holder member 14 are formed in capable of being fitted so as to be kept substantially air-tight and water-tight under pressure reduced state.

摘要翻译： 根据本发明的液体过滤装置10通过减压过滤实现过滤液体，并且其包括其中容纳有液体过滤器15的过滤构件12和用于储存通过液体过滤器15的过滤液体的保持构件14 ，其中过滤构件12和保持器构件14形成为能够被装配成在压力降低状态下基本上保持气密性和水密性。