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公开(公告)号：US20240336735A1
公开(公告)日：2024-10-10
申请号：US18749779
申请日：2024-06-21
发明人： Chaoxu SUN , Wanzhong CHEN , Xiang GAO , Xiucai LIU
IPC分类号： C08G69/28 , C08K3/22 , D01D4/06 , D01D5/084 , D01D5/088 , D01D5/096 , D01D5/098 , D01F1/10 , D01F6/60
CPC分类号： C08G69/28 , C08K3/22 , D01D4/06 , D01D5/084 , D01D5/088 , D01D5/096 , D01D5/098 , D01F1/10 , D01F6/60 , C08K2003/2241 , C08K2201/005 , D10B2331/02 , D10B2401/02 , D10B2401/061 , D10B2401/063 , D10B2401/14
摘要： A polyamide 56 resin, a fiber, a preparation method therefor and use thereof are provided. The method for preparing the polyamide 56 resin comprises a step of preparing the polyamide 56 resin from monomers by a polymerization reaction, wherein the polyamide 56 resin contains titanium dioxide, and the titanium dioxide is added during polymerization. The method for preparing the polyamide 56 resin in an embodiment can effectively prevent problems such as monofilament breakage and poor dyeing performance in a subsequent spinning process. In addition, the method is simple and easy to operate, and has a low production cost.
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22.发明公开公开(公告)号：US20240254522A1
公开(公告)日：2024-08-01
申请号：US18638860
申请日：2024-04-18
发明人： Wenbo LIU , Min XU , Chen YANG , Xiucai LIU
CPC分类号： C12P7/44 , C12N15/52 , C12Y103/03006
摘要： The present invention relates to a long-chain dibasic acid with low content of long-chain dibasic acid impurity of shorter carbon chain, to the preparation of a long-chain dibasic acid producing strain by directed evolution of POX gene and homologous recombination, and to the production of a long-chain dibasic acid with low content of long-chain dibasic acid impurity of shorter carbon chain by using the strain. The present invention also relates to a strain containing a mutated promoter, wherein, when a long-chain dibasic acid is produced by fermentation of this strain, the content of the acid impurity of shorter carbon chain in the fermentation product is significantly reduced.
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23.发明公开公开(公告)号：US20240174806A1
公开(公告)日：2024-05-30
申请号：US18432799
申请日：2024-02-05
发明人： Wutong FENG , Yuanbo ZHAO , Xiucai LIU
IPC分类号： C08G69/26
CPC分类号： C08G69/265
摘要： The present application provides a high temperature resistant semi-aromatic polyamide resin and a preparation method thereof, a composition, and an article. Polymeric monomers of the polyamide resin include a diamine monomer and a diacid monomer, where the diamine monomer includes a diamine monomer A1 and a diamine monomer A2, and the diacid monomer includes a diacid monomer B1 and a diacid monomer B2. The carbon atom number CA1 of the diamine monomer A1 and the carbon atom number CA2 of the diamine monomer A2 satisfy that CA1−CA2≥4, the diacid monomer B1 is selected from aromatic dicarboxylic acids with a carbon atom number of 7-12 and derivatives thereof, and the diacid monomer B2 is selected from aliphatic dicarboxylic acids with a carbon atom number of 4-18.
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24.发明申请公开(公告)号：US20200239919A1
公开(公告)日：2020-07-30
申请号：US16826606
申请日：2020-03-23
发明人： Wenbo LIU , Min XU , Chen YANG , Howard CHOU , Xiucai LIU
摘要： The invention relates to a long-chain dibasic acid with low content of monobasic acid impurity and a production method thereof, in particular to the preparation of a long-chain dibasic acid producing strain by means of directed evolution and homologous recombination, and to the production of a long-chain dibasic acid with low content of monobasic acid impurity by fermentation of said strain. The invention relates to a mutated CYP52A12 gene, homologous gene or variant thereof, which, relative to GenBank Accession Number AY230498 and taking the first base upstream of the start codon ATG as −1, comprises a mutation. The invention relates to a strain comprising said mutated CYP52A12 gene, homologous gene or variant thereof wherein when the strain is fermented to produce a long-chain dibasic acid, the content of monobasic acid impurity in the fermentation product is significantly reduced.
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25.发明申请公开(公告)号：US20190194705A1
公开(公告)日：2019-06-27
申请号：US16325610
申请日：2016-08-15
发明人： Howard CHOU , Xiucai LIU
CPC分类号： C12P13/08 , C07K14/195 , C12N1/20 , C12N9/88 , C12N15/52 , C12N15/70 , C12N15/74 , C12N2510/02 , C12P13/001 , C12R1/15 , C12R1/19 , C12Y401/01018
摘要： Provided herein is a genetically modified host cell comprising a heterologous nucleic acid encoding a biofilm dispersal polypeptide that decreases intracellular c-di-GMP levels and enhances the production of lysine and lysine derivatives. Further provided are methods of generating such cell and producing lysine and lysine derivatives using the genetically modified host cell.
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公开(公告)号：US20190330614A1
公开(公告)日：2019-10-31
申请号：US16473215
申请日：2016-12-30
发明人： Howard CHOU , Ling CHEN , Wenqiang LU , Xiucai LIU
摘要： The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mutant polypeptides, and methods of generating such microorganisms.
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公开(公告)号：US20200231999A1
公开(公告)日：2020-07-23
申请号：US16473149
申请日：2016-12-30
发明人： Howard CHOU , Wenqiang LU , Ling CHEN , Xiucai LIU
摘要： The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mutant polypeptides, and methods of generating such microorganism.
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