公开(公告)号：US20130314777A1

公开(公告)日：2013-11-28

申请号：US13896217

申请日：2013-05-16

Applicant: OLYMPUS CORPORATION

Inventor： Masahito DOHI

IPC: G02B27/30 ,  G02B21/06 ,  F21V5/04

CPC classification number: G02B27/30 ,  F21V5/04 ,  G02B21/0032 ,  G02B21/0076 ,  G02B21/06 ,  G02B21/16 ,  G02B21/26

Abstract: A collimator lens is configured with a double convex single lens formed with a resinous material, for collimating a light flux emitted from a light source. At least one of surfaces of the collimator lens is formed as an aspherical surface. The collimator lens satisfies following conditions: 2 0.6, where R1 is a curvature radius of a first surface, which is a lens surface on a side of the light source of the collimator lens, R2 is a curvature radius of a second surface, which is a lens surface on a side opposite to the first surface of the collimator lens, and NA is a numerical aperture on the side of the light source of the collimator lens.

Abstract translation: 准直透镜配置有由树脂材料形成的双凸单透镜，用于准直从光源发射的光束。 准直透镜的至少一个表面形成为非球面。 准直透镜满足以下条件：2 <| R1 / R2 | <10; NA> 0.6，其中R1是作为准直透镜的光源一侧的透镜面的第一面的曲率半径，R2是作为侧面的透镜面的第二面的曲率半径 与准直透镜的第一表面相对，NA是准直透镜的光源侧的数值孔径。

公开(公告)号：US20210027043A1

公开(公告)日：2021-01-28

申请号：US17025372

申请日：2020-09-18

Applicant: OLYMPUS CORPORATION

Inventor： Masahito DOHI

IPC: G06K9/00 ,  H04N5/225 ,  G02B23/24 ,  C12M1/34 ,  C12M1/00 ,  G01N15/06

Abstract: An observation device includes: an illumination unit that generates illumination light to be radiated onto cells floating in a culture fluid inside a culture vessel; a light receiving unit that receives observation light coming from the cells that have been irradiated with the illumination light, the observation light being imaged by an image-forming optical system; and a casing that has a transmissive section so as to transmit the illumination light and the observation light and that accommodates the illumination unit and the light receiving unit, wherein the casing has an elongated cylindrical form that is configured to be inserted into the culture fluid via a port used to insert a tube into the culture vessel.

公开(公告)号：US20200371337A1

公开(公告)日：2020-11-26

申请号：US16988828

申请日：2020-08-10

Applicant: OLYMPUS CORPORATION

Inventor： Masahito DOHI ,  Motohiro SHIBATA

IPC: G02B21/36 ,  G06T5/00 ,  G06T5/40 ,  G06T5/50

Abstract: An image processing device is configured to: generate a histogram of pixel values of a plurality of pixels contained in an image; set a background pixel value by using a peak value of the generated histogram; set a noise range with respect to the set background pixel value; and replace the pixel values that fall in the set noise range with a single arbitrary pixel value.

公开(公告)号：US20190113729A1

公开(公告)日：2019-04-18

申请号：US16140940

申请日：2018-09-25

Applicant: OLYMPUS CORPORATION

Inventor： Masahito DOHI

IPC: G02B21/00

Abstract: A microscope apparatus includes an illumination optical system. The illumination optical system includes an illumination lens that irradiates a sample with light, and two or more reflection members that have a shift function for changing a light-reflection position and/or a rotation function for changing a light-reflection-angle direction. Each of the two or more reflection members is located at a pupil position of the illumination lens, a position pupil-conjugate to the illumination lens, or a position conjugate to a rear focal position of the illumination lens.

公开(公告)号：US20160274345A1

公开(公告)日：2016-09-22

申请号：US15060585

申请日：2016-03-03

Applicant: OLYMPUS CORPORATION

Inventor： Makio UENO ,  Masahito DOHI ,  Atsuhiro TSUCHIYA ,  Hiroyasu HEBIISHI

IPC: G02B21/00 ,  G01N21/64 ,  G02B27/00 ,  G02B21/36 ,  G02B27/14

CPC classification number: G02B21/0076 ,  A61B5/0059 ,  A61B5/0062 ,  G01N21/6402 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0032 ,  G02B21/0084 ,  G02B21/361 ,  G02B27/0025 ,  G02B27/141

Abstract: A fluorescence observation unit includes a scanner that scans ultrashort pulsed laser light, a pupil projection lens that focuses the scanned ultrashort pulsed laser light, an image-forming lens that converts the focused ultrashort pulsed laser light to substantially collimated light and causes the ultrashort pulsed laser light to be incident on the objective lens, and a dichroic mirror that splits off, from the optic path of the ultrashort pulsed laser light, fluorescence generated in a sample due to irradiation with the ultrashort pulsed laser light and collected by the objective lens. The image-forming lens includes a first optical system having positive refractive power, and a second optical system having negative refractive power and disposed at a position closer to the scanner than the first optical system is. The dichroic mirror is disposed between the first optical system and the second optical system.

Abstract translation: 荧光观察单元包括扫描超短脉冲激光的扫描器，聚焦扫描的超短脉冲激光的瞳孔投影透镜，将聚焦的超短脉冲激光转换成基本准直的光并使超短脉冲激光 入射在物镜上的光和从超短脉冲激光的光路分离的二向色镜，由于用超短脉冲激光照射并由物镜收集而在样品中产生的荧光。 图像形成透镜包括具有正屈光力的第一光学系统和具有负屈光力的第二光学系统，并且设置在比第一光学系统更靠近扫描仪的位置处。 分色镜设置在第一光学系统和第二光学系统之间。

公开(公告)号：US20160241758A1

公开(公告)日：2016-08-18

申请号：US15041330

申请日：2016-02-11

Applicant: OLYMPUS CORPORATION

Inventor： Masahito DOHI ,  Yu KIKUCHI

IPC: H04N5/225 ,  G02B21/16 ,  G02B21/36 ,  H04N5/232

CPC classification number: H04N5/2256 ,  G02B21/16 ,  G02B21/361

Abstract: An object of the present invention is to obtain clear images when observing a specimen at different positions in the optical-axis direction of a detection optical system, using the sheet illumination. A fluorescence microscope of the present invention includes a sheet-illumination optical system that causes sheet-like excitation light along a plane of incidence to be incident on a specimen; an image-acquisition optical system that includes an objective lens having an optical axis intersecting the plane of incidence and that images fluorescence collected by the objective lens to obtain a fluorescence image; a driving part that moves the specimen in the optical-axis direction of the objective lens; and a positional-shift correction unit that, when a focus position of the image-acquisition optical system relative to an illumination position of the excitation light changes due to movement of the specimen in the optical-axis direction by the driving part, corrects a positional shift between the illumination position of the excitation light and the focus position of the image-acquisition optical system.

Abstract translation: 本发明的目的在于，使用片材照明，在检测光学系统的光轴方向上的不同位置观察样本时获得清晰的图像。 本发明的荧光显微镜包括使沿着入射面的片状激发光入射到试样上的片状照明光学系统; 图像采集光学系统，包括具有与入射平面相交的光轴的物镜，以及由物镜收集的图像以获得荧光图像; 驱动部，使所述检体沿所述物镜的光轴方向移动; 以及位置偏移校正单元，当所述摄像光学系统的相对于所述激发光的照明位置的焦点位置由于所述驱动部分的所述样本在光轴方向上的移动而改变时，校正位置 激发光的照明位置与摄像光学系统的焦点位置之间的偏移。