-
公开(公告)号:US20170191928A1
公开(公告)日:2017-07-06
申请号:US15315433
申请日:2015-05-18
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Hiroshi SATOZONO
CPC classification number: G01N21/19 , G01J4/04 , G01N2021/216
Abstract: Circular dichroism can be accurately measured even when a phase modulation element with a distortion component is used.A circular dichroism measuring method using a circular dichroism measuring device 2 includes a step of measuring Ip(t) (S101: phase amount change acquisition step), a step of measuring Is(t) (S102: sample data acquisition step), a step of converting Ip(t) to δ(t) (S103: phase amount change acquisition step), a step of converting Is(t) to Is(δ) (S104: analysis step/Is(δ) calculation step), and a step of performing curve fitting to calculate matrix elements S00, S02, and S03 (S105: analysis step/matrix element calculation step).
-
公开(公告)号:US20240418641A1
公开(公告)日:2024-12-19
申请号:US18703413
申请日:2022-10-26
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuhiro TAKAHASHI , Kouichiro AKIYAMA , Hiroshi SATOZONO
IPC: G01N21/3581 , G01N21/3563
Abstract: A crystal form determination method includes a first process of preparing a measurement target object; a second process of entering a terahertz wave to the measurement target object and detecting the terahertz wave from the measurement target object to acquire a plurality of detection results corresponding to a plurality of times separated from each other; and a third process of determining a type of crystal form contained in the measurement target object. In the third process, when a frequency characteristic having a third peak at a third frequency different from a first frequency related to a first peak corresponding to an anhydride and a second frequency related to a second peak corresponding to a hydrate exists among the plurality of frequency characteristics, determination is made that the crystal form different from the anhydride and the hydrate is contained in the measurement target object.
-
公开(公告)号:US20210010934A1
公开(公告)日:2021-01-14
申请号:US16916402
申请日:2020-06-30
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Atsushi NAKANISHI , Hiroshi SATOZONO
IPC: G01N21/55 , G01N21/3581
Abstract: Provided is a polymer resin orientation evaluation method including: setting an axis intersecting a front surface of an object to be inspected as an inspection axis, and acquiring an optical characteristic value of the object to be inspected with respect to a plurality of polarization directions of a terahertz wave around the inspection axis; and evaluating orientation of a polymer resin that constitutes the object to be inspected on the basis of a variation amount of the optical characteristic value with respect to change of the polarization direction.
-
14.
公开(公告)号:US20190056324A1
公开(公告)日:2019-02-21
申请号:US15763935
申请日:2016-09-08
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Akinori ODA , Hiroshi SATOZONO , Tomomi SHINKE , Yohei TAKATA
Abstract: The present invention relates to a method for detecting an amyloid β oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1
-
公开(公告)号:US20180273497A1
公开(公告)日:2018-09-27
申请号:US15762166
申请日:2016-09-27
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Hiroshi SATOZONO
IPC: C07D277/66 , G01N33/52 , G01N33/68
CPC classification number: C07D277/66 , C09B57/00 , C09K11/06 , G01N33/52 , G01N33/6896 , G01N2333/4709 , G01N2800/2821
Abstract: The present invention relates to a method for purifying pure thioflavin T having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent and a step of carrying out liquid-liquid extraction of the thioflavin T solution with a non-polar solvent.
-
公开(公告)号:US20240218140A1
公开(公告)日:2024-07-04
申请号:US18397004
申请日:2023-12-27
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Atsushi NAKANISHI , Yuta KINE , Takeshi WATARI , Takashi KURITA , Hiroshi SATOZONO
IPC: C08J7/12
CPC classification number: C08J7/123 , C08J2323/12 , C08J2355/02 , C08J2377/02 , C08J2497/02
Abstract: Provided is a method of manufacturing a resin member. The method includes irradiating a surface of a member containing a resin and a plant powder dispersed in the resin with laser light to change the plant powder or both the resin and the plant powder into diamond-like carbon in a surface layer region including the surface of the member.
-
公开(公告)号:US20230304926A1
公开(公告)日:2023-09-28
申请号:US18120533
申请日:2023-03-13
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Hisanari TAKAHASHI , Koyo WATANABE , Hiroshi SATOZONO , Kyohei SHIGEMATSU , Takashi INOUE
CPC classification number: G01N21/39 , G01N21/27 , G01N21/314 , G01N2021/1789
Abstract: A time response measurement apparatus includes a pulse formation unit, an attenuation unit, a waveform measurement unit, and an analysis unit. The pulse formation unit generates first pulsed light including a wavelength of pump light, second pulsed light including a wavelength of probe light, and third pulsed light including the wavelength of the pump light and the wavelength of the probe light, on a common optical axis. The attenuation unit transmits the first pulsed light, the second pulsed light, and the third pulsed light output from a sample arranged on the optical axis after being incident on the sample. An attenuation rate for the pump light is larger than an attenuation rate for the probe light. The analysis unit obtains a time response of the sample based on temporal waveforms of the first pulsed light, the second pulsed light, and the third pulsed light having passed through the attenuation unit.
-
公开(公告)号:US20220404280A1
公开(公告)日:2022-12-22
申请号:US17839568
申请日:2022-06-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Akinori ODA , Hiroshi SATOZONO
IPC: G01N21/64
Abstract: Provided is a method of quantifying a target substance present in a solvent comprises acquiring a first fluorescence decay curve and a second fluorescence decay curve to acquire some factors from the curves.
-
公开(公告)号:US20220236416A1
公开(公告)日:2022-07-28
申请号:US17569592
申请日:2022-01-06
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Hisanari TAKAHASHI , Koyo WATANABE , Hiroshi SATOZONO , Takashi INOUE
Abstract: An optical measurement device includes a light pulse source, a light separator unit, a wave synthesizer unit, an optical detection unit, and a measurement unit. The light pulse source outputs a plurality of light pulses having different temporal waveforms and different center wavelengths. The light separator unit spatially separates the light pulses and causes the light pulses to be incident on a measurement object. The wave synthesizer unit synthesizes the light pulses reflected by the measurement object or transmitted through the measurement object and emits the synthesized light pulses onto one optical path. The optical detection unit receives the light pulses emitted from the wave synthesizer unit and outputs a temporal waveform signal of the light pulses. The measurement unit measures timings when the light pulses each are received by the optical detection unit or a difference between the timings on a basis of the temporal waveform signal.
-
公开(公告)号:US20190271642A1
公开(公告)日:2019-09-05
申请号:US16285274
申请日:2019-02-26
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuki HORITA , Yoichi KAWADA , Atsushi NAKANISHI , Kazuue FUJITA , Hironori TAKAHASHI , Hiroshi SATOZONO
IPC: G01N21/3586 , G01N21/552 , G01J3/42
Abstract: An optical measurement device includes a light source configured to output a terahertz wave and coaxial light having a wavelength different from the wavelength of the terahertz wave, coaxially with the terahertz wave; an intensity modulation unit configured to perform intensity modulation of at least the terahertz wave of the terahertz wave and the coaxial light in a predetermined modulation frequency; and a light detection unit configured to synchronously detects each of the terahertz wave and the coaxial light which have acted on a measurement subject via the intensity modulation unit based on the modulation frequency.
-
-
-
-
-
-
-
-
-