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公开(公告)号:US20200255539A1
公开(公告)日:2020-08-13
申请号:US16721525
申请日:2019-12-19
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , G01N33/574 , C07K16/30 , A61K49/00 , A61K31/704 , A61K31/675 , A61K31/5517 , C07K16/28 , A61K39/395 , A61K47/68
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20200085840A1
公开(公告)日:2020-03-19
申请号:US16391738
申请日:2019-04-23
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K31/5517 , A61K47/68 , A61K39/395 , C07K16/00 , C07K16/32
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号:US10314846B2
公开(公告)日:2019-06-11
申请号:US15438418
申请日:2017-02-21
Applicant: GENENTECH, INC.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K39/395 , A61K31/5517 , A61K47/68 , C07K16/00 , C07K16/32
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号:US20160368994A1
公开(公告)日:2016-12-22
申请号:US15182327
申请日:2016-06-14
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2851 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/57 , C07K16/2803 , C07K16/2809 , C07K16/2827 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/52 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
Abstract translation: 本发明涉及包含CLL-1结合结构域和CD3结合结构域(例如,抗CLL-1 / CD3T细胞依赖性双特异性(TDB)抗体)的抗CLL-1抗体的抗CLL-1抗体, 使用方法
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公开(公告)号:US11466087B2
公开(公告)日:2022-10-11
申请号:US16658706
申请日:2019-10-21
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: A61K39/395 , C07K16/28 , C07K16/30 , A61K45/06 , A61K39/00
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号:US20200148774A1
公开(公告)日:2020-05-14
申请号:US16658706
申请日:2019-10-21
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号:US10556966B2
公开(公告)日:2020-02-11
申请号:US16170819
申请日:2018-10-25
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , A61K47/68 , A61K39/395 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K49/00 , C07K16/30
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20170274092A1
公开(公告)日:2017-09-28
申请号:US15438418
申请日:2017-02-21
Applicant: GENENTECH, INC.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K47/48 , C07K16/00 , A61K39/395 , C07K16/32 , A61K31/5517 , C07K19/00 , C07D487/16
CPC classification number: A61K31/5517 , A61K39/39558 , A61K47/6803 , A61K47/6855 , A61K47/6869 , C07K16/005 , C07K16/32 , C07K2317/24 , C07K2317/92
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号:US11939396B2
公开(公告)日:2024-03-26
申请号:US16916822
申请日:2020-06-30
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , C07K16/24 , A61K39/00 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26
CPC classification number: C07K16/40 , A61K39/3955 , A61K39/39591 , C07K16/244 , C12Y304/21059 , A61K2039/505 , A61K45/06 , A61K47/10 , A61K47/183 , A61K47/22 , A61K47/26 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号:US11530275B2
公开(公告)日:2022-12-20
申请号:US16790616
申请日:2020-02-13
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Teemu T. Junttila , Robert F. Kelley , Mary A. Mathieu
IPC: C07K16/28 , C07K16/32 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68 , A61K39/00
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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