-
公开(公告)号：US11732054B2
公开(公告)日：2023-08-22
申请号：US16790656
申请日：2020-02-13
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Teemu T. Junttila , Robert F. Kelley , Mary A. Mathieu
IPC: C07K16/28 , C07K16/32 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68 , A61K39/00
CPC classification number: C07K16/32 , A61K31/573 , A61K39/39558 , A61K45/06 , A61K47/6881 , C07K16/283 , C07K16/2809 , C07K16/2827 , C07K16/2863 , C07K16/2887 , C07K16/2896 , C07K16/30 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/71 , C07K2317/73 , C07K2317/92
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
-
公开(公告)号：US11530275B2
公开(公告)日：2022-12-20
申请号：US16790616
申请日：2020-02-13
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Teemu T. Junttila , Robert F. Kelley , Mary A. Mathieu
IPC: C07K16/28 , C07K16/32 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68 , A61K39/00
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
-
公开(公告)号：US11192950B2
公开(公告)日：2021-12-07
申请号：US16395009
申请日：2019-04-25
Applicant: Genentech, Inc.
Inventor： Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle Dicara , Diego Ellerman , Christoph Spiess , Paul J. Carter
IPC: C07H21/02 , C07H21/04 , C12P21/06 , C12P21/04 , C12N5/00 , C12N5/16 , C12N1/20 , C07K16/28 , A61K47/68 , A61K39/395 , A61K45/06 , C07K16/30 , G01N33/574 , C07K16/00 , A61K39/00
Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
-
公开(公告)号：US10435471B2
公开(公告)日：2019-10-08
申请号：US14313822
申请日：2014-06-24
Applicant: Genentech, Inc.
Inventor： Allen J. Ebens , Meredith C. Hazen , Jo-Anne Hongo , Jennifer W. Johnston , Teemu T. Junttila , Ji Li , Andrew G. Polson
IPC: C07K16/00 , C12P21/08 , C07K17/00 , A61K39/395 , A61K39/40 , C07K16/28 , A61K51/10 , A61K47/68 , C07K1/00 , A61K39/00
Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
-
公开(公告)号：US10323094B2
公开(公告)日：2019-06-18
申请号：US15184690
申请日：2016-06-16
Applicant: Genentech, Inc.
Inventor： Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle DiCara , Diego Ellerman , Christoph Spiess , Paul J. Carter
IPC: C07K16/00 , C12P21/08 , A61K39/395 , A61K39/40 , A61K39/42 , C07K16/28 , A61K45/06 , C07K16/30 , G01N33/574 , A61K47/68 , A61K39/00
Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
-
Patent Agency Ranking
公开(公告)号：US20240383984A1
公开(公告)日：2024-11-21
申请号：US18675452
申请日：2024-05-28
Applicant: Genentech, Inc.
Inventor： Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle Dicara , Diego Ellerman , Christoph Spiess , Paul J. Carter
IPC: C07K16/28 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/68 , C07K16/30 , G01N33/574
Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
-
公开(公告)号：US12030947B2
公开(公告)日：2024-07-09
申请号：US17514824
申请日：2021-10-29
Applicant: Genentech, Inc.
Inventor： Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle Dicara , Diego Ellerman , Christoph Spiess , Paul J. Carter
IPC: A61K39/395 , A61K39/40 , A61K45/06 , A61K47/68 , C07K16/28 , C07K16/30 , G01N33/574 , A61K39/00 , C07K16/00
CPC classification number: C07K16/283 , A61K39/39558 , A61K45/06 , A61K47/6849 , A61K47/6851 , C07K16/2809 , C07K16/2827 , C07K16/30 , G01N33/57492 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/62 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N2333/70535
Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
-
公开(公告)号：US20240092906A1
公开(公告)日：2024-03-21
申请号：US18517327
申请日：2023-11-22
Applicant: Genentech, Inc.
Inventor： Diego ELLERMAN , Teemu T. Junttila , Twyla Noelle Lombana , Dionysos Slaga , Christoph Spiess
IPC: C07K16/28 , A61K9/00 , A61K39/395 , A61K47/65 , A61P35/00 , A61P35/02 , C07K16/10 , C07K16/32 , C07K16/46
CPC classification number: C07K16/2809 , A61K9/0019 , A61K39/3955 , A61K47/65 , A61P35/00 , A61P35/02 , C07K16/1063 , C07K16/2803 , C07K16/2818 , C07K16/32 , C07K16/468
Abstract: The present invention provides bispecific antigen-binding molecules having a monovalent arm specific to a first target antigen (e.g., a T cell antigen, such as CD3) and a bivalent arm specific for a second target antigen (e.g., a tumor antigen, such as HER2). Bispecific antigen-binding molecules are useful in the treatment of disorders, such as cancer (e.g., HER2-positive cancer). The invention also features methods of producing bispecific antigen-binding molecules, methods of treating disorders using bispecific antigen-binding molecules, and compositions including bispecific antigen-binding molecules.
-
公开(公告)号：US11866498B2
公开(公告)日：2024-01-09
申请号：US16271410
申请日：2019-02-08
Applicant: Genentech, Inc.
Inventor： Diego Ellerman , Teemu T. Junttila , Twyla Noelle Lombana , Dionysos Slaga , Christoph Spiess
IPC: C07K16/28 , A61P35/00 , C07K16/32 , A61K39/395 , A61K47/65 , A61K9/00 , C07K16/46 , C07K16/10 , A61P35/02
CPC classification number: C07K16/2809 , A61K9/0019 , A61K39/3955 , A61K47/65 , A61P35/00 , A61P35/02 , C07K16/1063 , C07K16/2803 , C07K16/2818 , C07K16/32 , C07K16/468
Abstract: The present invention provides bispecific antigen-binding molecules having a monovalent arm specific to a first target antigen (e.g., a T cell antigen, such as CD3) and a bivalent arm specific for a second target antigen (e.g., a tumor antigen, such as HER2). Bispecific antigen-binding molecules are useful in the treatment of disorders, such as cancer (e.g., HER2-positive cancer). The invention also features methods of producing bispecific antigen-binding molecules, methods of treating disorders using bispecific antigen-binding molecules, and compositions including bispecific antigen-binding molecules.
-
公开(公告)号：US11352431B2
公开(公告)日：2022-06-07
申请号：US16583584
申请日：2019-09-26
Applicant: Genentech, Inc.
Inventor： Allen J. Ebens , Meredith C. Hazen , Jo-Anne Hongo , Jennifer W. Johnston , Teemu T. Junttila , Ji Li , Andrew G. Polson
IPC: C07H21/04 , C07H21/02 , C12P21/06 , C12P21/04 , C12N5/02 , C12N5/16 , C07K16/28 , A61K47/68 , A61K39/395 , A61K51/10 , C07K16/00 , A61K39/00
Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.011 seconds)
