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公开(公告)号:US20180362620A1
公开(公告)日:2018-12-20
申请号:US15821062
申请日:2017-11-22
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Mary Mathieu
Abstract: The present invention relates to anti-Ebola virus envelope glycoprotein antibodies. The invention further relates to diagnostic methods which utilize the anti-Ebola virus glycoprotein antibodies and to pharmaceutical compositions which employ these antibodies therapeutically and prophylactically.
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公开(公告)号:US20180094056A1
公开(公告)日:2018-04-05
申请号:US15842590
申请日:2017-12-14
Applicant: Genentech, Inc.
Inventor: Mary Mathieu , Mark Dennis
IPC: C07K16/28 , A61K39/395 , C07K16/32 , A61P35/00
CPC classification number: C07K16/2809 , A61K39/39558 , A61P35/00 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/73 , C07K2317/74 , C07K2317/92 , C07K2317/94
Abstract: The invention provides anti-HER2 antibodies, including anti-HER2 antibodies of improved stability or affinity, and methods of using the same.
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公开(公告)号:US20160368994A1
公开(公告)日:2016-12-22
申请号:US15182327
申请日:2016-06-14
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2851 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/57 , C07K16/2803 , C07K16/2809 , C07K16/2827 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/52 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
Abstract translation: 本发明涉及包含CLL-1结合结构域和CD3结合结构域(例如,抗CLL-1 / CD3T细胞依赖性双特异性(TDB)抗体)的抗CLL-1抗体的抗CLL-1抗体, 使用方法
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公开(公告)号:US11466087B2
公开(公告)日:2022-10-11
申请号:US16658706
申请日:2019-10-21
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: A61K39/395 , C07K16/28 , C07K16/30 , A61K45/06 , A61K39/00
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号:US20200148774A1
公开(公告)日:2020-05-14
申请号:US16658706
申请日:2019-10-21
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号:US10377825B2
公开(公告)日:2019-08-13
申请号:US15842590
申请日:2017-12-14
Applicant: Genentech, Inc.
Inventor: Mary Mathieu , Mark Dennis
IPC: A61K39/395 , C07K16/28 , C07K16/32 , A61P35/00
Abstract: The invention provides anti-HER2 antibodies, including anti-HER2 antibodies of improved stability or affinity, and methods of using the same.
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