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公开(公告)号：US11466087B2
公开(公告)日：2022-10-11
申请号：US16658706
申请日：2019-10-21
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: A61K39/395 , C07K16/28 , C07K16/30 , A61K45/06 , A61K39/00
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号：US20200148774A1
公开(公告)日：2020-05-14
申请号：US16658706
申请日：2019-10-21
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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3.发明申请公开(公告)号：US20140106374A1
公开(公告)日：2014-04-17
申请号：US14078241
申请日：2013-11-12
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/68
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US09017951B2
公开(公告)日：2015-04-28
申请号：US13673565
申请日：2012-11-09
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/53 , G01N33/574 , A61K39/395 , A61K45/06 , C07K16/28 , A61K31/69 , A61K39/00
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: A method of determining the presence of FcRH5 in a biological sample suspected of containing FcRH5 is provided comprising exposing the biological sample to an isolated monoclonal anti-FcRH5 antibody.
Abstract translation: 提供了一种确定怀疑含有FcRH5的生物样品中FcRH5存在的方法，包括将生物样品暴露于分离的单克隆抗FcRH5抗体。
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Patent Agency Ranking
公开(公告)号：US08617559B2
公开(公告)日：2013-12-31
申请号：US13682581
申请日：2012-11-20
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20130089555A1
公开(公告)日：2013-04-11
申请号：US13682581
申请日：2012-11-20
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: C07K16/28 , A61K38/19 , A61K31/56 , A61K39/00 , A61K31/69 , A61K33/24 , A61K31/138 , A61K31/4196 , A61K31/5685 , A61K31/4745 , A61K31/568 , A61K31/517 , A61K39/395 , A61K31/454
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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7.发明申请公开(公告)号：US20130089497A1
公开(公告)日：2013-04-11
申请号：US13673565
申请日：2012-11-09
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/395 , A61K31/69
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20160368994A1
公开(公告)日：2016-12-22
申请号：US15182327
申请日：2016-06-14
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2851 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/57 , C07K16/2803 , C07K16/2809 , C07K16/2827 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/52 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
Abstract translation: 本发明涉及包含CLL-1结合结构域和CD3结合结构域（例如，抗CLL-1 / CD3T细胞依赖性双特异性（TDB）抗体）的抗CLL-1抗体的抗CLL-1抗体， 使用方法
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公开(公告)号：US09360484B2
公开(公告)日：2016-06-07
申请号：US14078241
申请日：2013-11-12
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: C07K16/00 , G01N33/68 , A61K47/48 , C07K16/28 , G01N33/574 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/395 , A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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