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    IDENTIFICATION OF GENETIC VARIANTS
    12.
    发明申请
    IDENTIFICATION OF GENETIC VARIANTS 有权
    遗传变异的鉴定

    公开(公告)号：US20150098937A1

    公开(公告)日：2015-04-09

    申请号：US14323775

    申请日：2014-07-03

    Applicant: Randox Laboratories Ltd.

    Inventor： JOHN V. LAMONT

    IPC: C12Q1/68

    CPC classification number: C12Q1/6883 ,  A61K31/404 ,  A61K31/4439 ,  A61K31/517 ,  C12Q2600/106 ,  C12Q2600/156

    Abstract: The present disclosure provides a method for identifying whether a subject is more or less likely to be responsive to VEGF-based therapy, comprising screening a nucleic acid sample obtained from the subject to provide output information which identifies the presence or absence of an allelic variant, wherein the presence or absence of an allelic variant indicates whether the subject is more or less likely to be responsive to VEGF-based therapy.

    Abstract translation: 本公开提供了用于鉴定受试者是或多或少可能对基于VEGF的治疗有反应的方法，其包括筛选从受试者获得的核酸样品以提供识别等位变体的存在或不存在的输出信息， 其中等位基因变体的存在或不存在表明受试者是或多或少可能对基于VEGF的治疗有反应。

    Assay device processing instrument
    13.
    发明申请
    Assay device processing instrument 有权
    测定装置处理仪器

    公开(公告)号：US20040191890A1

    公开(公告)日：2004-09-30

    申请号：US10643926

    申请日：2003-08-20

    Applicant: RANDOX LABORATORIES LTD

    Inventor： James Rudolf Meyer ,  Ahti Kalevi Kansanaho ,  Stephen Peter Fitzgerald ,  Robert Ivan McConnell ,  John Victor Lamont ,  Bailin Cao

    IPC: C12M001/34

    CPC classification number: G01N35/028 ,  G01N35/00029 ,  G01N35/0099 ,  G01N2035/00158 ,  G01N2035/00326 ,  G01N2035/0425 ,  Y10T436/113332

    Abstract: An assay device processing instrument comprises a plurality of processing modules. A transport system transports an assay device to each processing module, the transport system being adapted to transfer the assay device from the transport system to the module to enable the transport system to transport another assay device while the first is processed by the processing module. A control system controls operation of the transport system such that each assay device is transferred between the modules in a predetermined sequence, and such that a number of assay devices can be processed in different modules simultaneously.

    Abstract translation: 测定装置处理装置包括多个处理模块。 运输系统将测定装置运送到每个处理模块，所述运输系统适于将测定装置从运输系统传送到模块，以使得运输系统能够在第一个由处理模块处理的同时运送另一个测定装置。 控制系统控制运输系统的操作，使得每个测定装置以预定顺序在模块之间转移，并且使得可以同时在不同模块中处理多个测定装置。

    Multi-analyte immunoassay
    15.
    发明申请
    Multi-analyte immunoassay 审中-公开
    多分析物免疫测定

    公开(公告)号：US20020086337A1

    公开(公告)日：2002-07-04

    申请号：US09949756

    申请日：2001-09-12

    Applicant: RANDOX LABORATORIES LTD.

    Inventor： Stephen Peter Fitzgerald ,  John Victor Lamont ,  Robert Ivan McConnell

    IPC: G01N033/53 ,  G01N033/542 ,  G01N033/536

    CPC classification number: G01N33/94 ,  G01N33/54306

    Abstract: An assay for an analyte in a sample, wherein the sample is contacted with an array of ligands including a ligand specific for the analyte, additionally comprises including a scavenger material that binds the analyte and thereby reduces its available concentration.

    Abstract translation: 样品中分析物的分析物，其中样品与包括对分析物特异性的配体的配体阵列接触，另外包括包含结合分析物的清除剂材料，从而降低其可用浓度。

    Sample Extractor
    17.
    发明公开
    Sample Extractor 审中-公开

    公开(公告)号：US20240310400A1

    公开(公告)日：2024-09-19

    申请号：US18576835

    申请日：2022-07-08

    Applicant: RANDOX LABORATORIES LTD.

    Inventor： James DAVIDSON ,  Ivan MCCONNELL ,  Peter FITZGERALD

    IPC: G01N35/10 ,  G01N1/14 ,  G01N35/00 ,  G01N35/04

    CPC classification number: G01N35/1011 ,  G01N1/14 ,  G01N35/00732 ,  G01N2035/00277 ,  G01N2035/0405

    Abstract: There is provided an apparatus and method for extracting a biological sample from a sample container. The apparatus comprising: a holder arranged in use to support a sample container; an extractor moveable in use between a first position disengaged from the container when the container is supported by the holder and a second position engaged with the container when the container is supported by the holder, the extractor being arranged in use to obtain matter from the container when in the second position; and an imager arranged in use to capture an image of the extractor at the first position when the extractor is moved from the second position to the first position and to identify, based on analysis of the captured image, when sample is present outside the container.

    VISION SYSTEM
    18.
    发明公开
    VISION SYSTEM 审中-公开

    公开(公告)号：US20240296539A1

    公开(公告)日：2024-09-05

    申请号：US18572687

    申请日：2022-07-01

    Applicant: Randox Laboratories Ltd.

    Inventor： Deepesh UPADHYAY ,  Peter FITZGERALD ,  Ivan MCCONNELL

    IPC: G06T7/00 ,  H04N23/56 ,  H04N23/695

    CPC classification number: G06T7/0004 ,  H04N23/56 ,  H04N23/695 ,  G06T2207/30072

    Abstract: There is provided a vision system for assessing defects on biochips and a corresponding method. The vision system comprises an imaging region in which a biochip sheet including at least one biochip is locatable in use: an imager arranged in use to image at least a portion of the imaging region, wherein, when the biochip sheet is located in the imaging region. the portion includes at least a face of the biochip sheet: and an illumination source arranged in use to direct illumination on to the face the biochip sheet. thereby illuminating defects on the at least one biochip when a mask material layer is present on the at least one biochip and when a mask material is absent and allowing the defects to be included in the imaged at least a portion of the imaging region.

    Chemiluminescence detector sample enclosure
    19.
    发明授权
    Chemiluminescence detector sample enclosure 有权

    公开(公告)号：US11988607B2

    公开(公告)日：2024-05-21

    申请号：US16632270

    申请日：2018-07-18

    Applicant: Randox Laboratories Ltd

    Inventor： Marc Wharry ,  P. Evans ,  Stuart Jackson

    IPC: B01L3/00 ,  G01N21/76

    CPC classification number: G01N21/76 ,  B01L3/50855 ,  B01L2200/02 ,  B01L2200/0689

    Abstract: There is provided a chemiluminescence detector sample enclosure. The enclosure comprises a first interface member forming part of a chemiluminescence detector and having a first sealing element and a second interface member comprising a plurality of sample holders, each sample holder having a second sealing element. The first interface member is engagable with and moveable between sample holder subsets of the plurality of sample holders, engagement with a respective sample holder subset providing engagement of the first interface member with each sample holder of the respective sample holder subset and relative movement of the first and second interface members providing movement between sample holder subsets; and when the first interface member is engaged with each respective sample holder, the first sealing element and the respective second sealing element are adapted to interact so as to form a light restricting seal between the first interface member and said sample holder.

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