公开(公告)号：US20230406933A1

公开(公告)日：2023-12-21

申请号：US18035070

申请日：2021-11-02

Applicant: Randox Laboratories Ltd.

Inventor： Marshall Dunlop ,  Shirley Schon ,  John Lamont ,  Peter Fitzgerald

IPC: C07K16/28

CPC classification number: C07K16/2827 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2317/33 ,  C07K2317/22 ,  C07K2317/94 ,  C07K2317/76

Abstract: The present invention relates to therapeutic antibodies, or antigen-binding portions thereof, for use in the treatment of cancer and infectious disease. Specifically, the present invention relates to therapeutic antibodies, or antigen-binding portions thereof, that target the programmed death-ligand 1 polypeptide. The present invention also relates to pharmaceutical compositions comprising said therapeutic antibody, or antigen-binding portions thereof.