Nematicidal compositions and methods
    11.
    发明授权
    Nematicidal compositions and methods 有权
    杀线虫组合物和方法

    公开(公告)号:US06887900B2

    公开(公告)日:2005-05-03

    申请号:US10090527

    申请日:2002-03-04

    摘要: The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes parasitizing animals can also be controlled using the methods and composition of this invention. The useful compounds are inhibitors of nematode delta-12 fatty acid desaturases and can be, for example, from C16 to C20 in length. A feature of these compounds is that their inhibitory effect on the activity of a nematode delta-12 desaturase, or on the viability or fecundity of a nematode, is smaller in the presence of the product of a delta-12 fatty acid desaturase (e.g., linoleate) than in the presence of the substrate of the enzyme (e.g., oleate).

    摘要翻译: 本发明涉及使用某些与脂肪酸有关的化合物来控制侵染植物或植物部位的线虫。 寄生动物的线虫也可以使用本发明的方法和组合来控制。 有用的化合物是线虫δ-12脂肪酸去饱和酶的抑制剂,并且可以是例如C16至C20的长度。 这些化合物的特征在于,在δ-12脂肪酸去饱和酶的产物存在下,它们对线虫δ-12去饱和酶的活性的抑制作用或线虫的活力或繁殖力较小, 亚油酸酯)比在酶的底物(例如油酸酯)的存在下。

    Nematode MDH-like sequences
    19.
    发明授权
    Nematode MDH-like sequences 有权
    线虫MDH样序列

    公开(公告)号:US06743612B1

    公开(公告)日:2004-06-01

    申请号:US10060848

    申请日:2002-01-30

    IPC分类号: C12N904

    CPC分类号: C12N9/0006

    摘要: Disclosed are two nucleic acid molecules from M. incognita encoding malate dehydrogenase-like (MDH-like) polypeptides. The MDH-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of MDH-like nucleotides and polypeptides. The invention further relates to screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.

    摘要翻译: 公开了来自编码苹果酸脱氢酶样(MDH样)多肽的不加共轭体的两个核酸分子。 还提供MDH样多肽序列,载体,宿主细胞以及用于产生MDH样核苷酸和多肽的重组方法。 本发明还涉及用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。